74 research outputs found
DISCO: a Spatio-Spectral Recombiner for Pupil Remapping Interferometry
Pupil-remapping is a new high-dynamic range imaging technique that has
recently demonstrated feasibility on sky. The current prototypes present
however deceiving limiting magnitude, restricting the current use to the
brightest stars in the sky. We propose to combine pupil-remapping with
spatio-spectral encoding, a technique first applied to the VEGA/CHARA
interferometer. The result is an instrument proposal, called "Dividing
Interferometer for Stars Characterizations and Observations" (DISCO). The idea
is to take profit of wavelength multiplexing when using a spectrograph in order
to pack as much as possible the available information, yet providing a
potential boost of 1.5 magnitude if used in existing prototypes. We detail in
this paper the potential of such a concept.Comment: Improving the performances of current optical interferometers \&
future designs, France (2013
Parasitic Interference in Long Baseline Optical Interferometry: Requirements for Hot Jupiter-like Planet Detection
International audienceThe observable quantities in optical interferometry, which are the modulus and the phase of the complex visibility, may be corrupted by parasitic fringes superimposed on the genuine fringe pattern. These fringes are due to an interference phenomenon occurring from stray light effects inside an interferometric instrument. We developed an analytical approach to better understand this phenomenon when stray light causes cross talk between beams. We deduced that the parasitic interference significantly affects the interferometric phase and thus the associated observables including the differential phase and the closure phase. The amount of parasitic flux coupled to the piston between beams appears to be very influential in this degradation. For instance, considering a point-like source and a piston ranging from λ/500 to λ/5 in the L band (λ = 3.5 μm), a parasitic flux of about 1% of the total flux produces a parasitic phase reaching at most one-third of the intrinsic phase. The piston, which can have different origins (instrumental stability, atmospheric perturbations, etc.), thus amplifies the effect of parasitic interference. According to the specifications of piston correction in space or at ground level (respectively λ/500 ≈ 2 nm and λ/30 ≈ 100 nm), the detection of hot Jupiter-like planets, one of the most challenging aims for current ground-based interferometers, limits parasitic radiation to about 5% of the incident intensity. This was evaluated by considering different types of hot Jupiter synthetic spectra. Otherwise, if no fringe tracking is used, the detection of a typical hot Jupiter-like system with a solar-like star would admit a maximum level of parasitic intensity of 0.01% for piston errors equal to λ/15. If the fringe tracking specifications are not precisely observed, it thus appears that the allowed level of parasitic intensity dramatically decreases and may prevent the detection. In parallel, the calibration of the parasitic phase by a reference star, at this accuracy level, seems very difficult. Moreover, since parasitic phase is an object-dependent quantity, the use of a hypothetical phase abacus, directly giving the parasitic phase from a given parasitic flux level, is also impossible. Some instrumental solutions, implemented at the instrument design stage for limiting or preventing this parasitic interference, appear to be crucial and are presented in this paper
Relaxation and emission of Bragg-mode and cavity-mode polaritons in a ZnO microcavity at room temperature
The strong coupling regime in a ZnO microcavity is investigated through room
temperature photoluminescence and reflectivity experiments. The simultaneous
strong coupling of excitons to the cavity mode and the first Bragg mode is
demonstrated at room temperature. The polariton relaxation is followed as a
function of the excitation density. A relaxation bottleneck is evidenced in the
Bragg-mode polariton branch. It is partly broken under strong excitation
density, so that the emission from this branch dominates the one from
cavity-mode polaritons
AMBER : a near infrared focal instrument for the VLTI
10 pagesInternational audienceAMBER is the General User near-infrared focal instrument of the Very Large Telescope interferometer. Its specifications are based on three key programs on Young Stellar Objects, Active Galactic Nuclei central regions, masses and spectra of hot Extra Solar Planets. It has an imaging capacity because it combines up to three beams and very high accuracy measurement are expected from the spatial filtering of beams by single mode fibers and the comparison of measurements made simultaneously in different spectral channels
Macrophage IL-1β-positive microvesicles exhibit thrombo-inflammatory properties and are detectable in patients with active juvenile idiopathic arthritis
ObjectiveIL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated disease such as systemic juvenile idiopathic arthritis (sJIA). Leukocyte microvesicles (MVs) may be a mechanism of IL-1β secretion. The first objective of our study was to characterize IL-1β-positive MVs obtained from macrophage cell culture supernatants and to investigate their biological functions in vitro and in vivo. The second objective was to detect circulating IL-1β-positive MVs in JIA patients.MethodsMVs were purified by serial centrifugations from PBMCs, or THP-1 differentiated into macrophages, then stimulated with LPS ± ATP. MV content was analyzed for the presence of IL-1β, NLRP3 inflammasome, caspase-1, P2X7 receptor, and tissue factor (TF) using ELISA, Western blot, or flow cytometry. MV biological properties were studied in vitro by measuring VCAM-1, ICAM-1, and E-selectin expression after HUVEC co-culture and factor-Xa generation test was realized. In vivo, MVs’ ability to recruit leukocytes in a murine model of peritonitis was evaluated. Plasmatic IL-1β-positive MVs were studied ex vivo in 10 active JIA patients using flow cytometry.ResultsTHP-1-derived macrophages stimulated with LPS and ATP released MVs, which contained NLRP3, caspase-1, and the 33-kDa precursor and 17-kDa mature forms of IL-1β and bioactive TF. IL-1β-positive MVs expressed P2X7 receptor and released soluble IL-1β in response to ATP stimulation in vitro. In mice, MVs induced a leukocyte peritoneal infiltrate, which was reduced by treatment with the IL-1 receptor antagonist. Finally, IL-1β-positive MVs were detectable in plasma from 10 active JIA patients.ConclusionMVs shed from activated macrophages contain IL-1β, NLRP3 inflammasome components, and TF, and constitute thrombo-inflammatory vectors that can be detected in the plasma from active JIA patients
Interest of interferometry for the study of the constituents of planetary systems
Cette thèse porte sur l'exploitation des capacités de haute résolution angulaire du VLTI pour l'observation directe des constituants des systèmes planétaires. A l'aide de l'instrument MIDI, nous avons obtenu les premières mesures de taille par interférométrie longue base de trois astéroïdes: (951) Gaspra, (234) Barbara, et (41) Daphne. L'application d'un modèle thermophysique aux données de MIDI a également permis de contraindre certains paramètres de surface (inertie thermique, rugosité). Ensuite, l'étude des planètes géantes extrasolaires est abordée par le biais de la première tentative d'observation d'une exoplanète géante, Gliese 86b, avec l'instrument MIDI. Une nouvelle méthode de calibration des effets chromatiques de la vapeur d'eau, utilisant les mesures de phase simultanées d'AMBER, est testée ici. A cause notamment de plusieurs compromis techniques liés à l'utilisation simultanée des deux instruments, la précision des données de MIDI, ainsi que la justesse de calibration à partir des données d'AMBER, se situent actuellement à un facteur 10 du signal planétaire. Via un modèle dynamique, j'ai également évalué l'impact des interactions entre disques de débris et planètes sur la composition des atmosphères planétaires. Dans le cas des planètes géantes du système solaire, les enrichissements résultants sont globalement inférieurs aux valeurs observées aujourd'hui mais restent significatifs pour Uranus et Neptune. Enfin, dans un contexte de développement d'interféromètres de nouvelle génération, une étude analytique est effectuée sur le problème des interférences parasites. Des spécifications sont définies par rapport à la détection des planètes extrasolaires géantes.This work is about the use of the high angular resolution capacities of the VLTI for the direct observation of the planetary systems components. By means of the MIDI instrument, we derived the first size measurements by long baseline interferometry of three asteroids: (951) Gaspra, (234) Barbara, and (41) Daphne. The application of a thermophysical model to MIDI data allowed to constrain several surface parameters (thermal inertia, roughness). Next, the study of extrasolar giant planets is addressed through the first attempt to observe a giant exoplanet, Gliese 86b, with the MIDI instrument. A new method of calibration of the chromatic effects of water vapour, using the simultaneous phase measurements of AMBER, is tested here. Because of several technical compromises related to the parallel operation of both instruments, the precision of MIDI data, along with the calibration accuracy from AMBER ones, currently stand at a factor 10 above the planetary signal. Using a dynamical model, i evaluated as well the impact of interactions between debris disks and planets, on the composition of planetary atmospheres. In the case of the giant planets of the solar system, the resulting enrichments are globally lower than the values currently observed, but remain significant for Uranus and Neptune. Finally, in a context of development of new generation interferometers, an analytical study is performed on the problem of parasitic interferences. Requirements are defined in relation to the detection of extrasolar giant planets.NICE-BU Sciences (060882101) / SudocSudocFranceF
Gametogenic cycle and reproductive effort of the tropical blacklip pearl oyster,
The gametogenic cycle and the reproductive effort of the blacklip pearl oyster, Pinctada margaritifera, cultivated in Takapoto lagoon were studied for a 1-year period (March 1997–April 1998) by bimonthly observations of gonadal sections, dry tissue weights and gonadal index in a population of pearl oyster composed of three age-groups. Pearl oysters attained sexual maturity in the end of their first year (height ≈ 40 mm), implying that P. margaritifera is a late-maturing species in comparison with other Pteriidae. This species was also confirmed to be a marked protandrous successive hermaphrodite in culture, with 100 % of males at first maturity and 75 % in older pearl oyster (height > 120 mm). The general pattern of gametogenic activity, fairly synchronous in both sexes, was comparable with that of other tropical bivalves: reproduction occurs continuously throughout the year with a maximal activity during the warm season (November–May). No resting period was observed. Quantitative growth data showed that P. margaritifera exhibits an annual synchronised polymodal spawning pattern, with two spawning peaks in age-group I (height ≈ 70 mm) and five in age-groups II (height ≈ 100 mm) and III (height ≈ 120 mm). Spawning was sometimes incomplete, nevertheless a clear relationship between gamete production (PR, g) and size (height H, mm) was obtained: PR = 5.26 × 10–7 H2.91 (R[sup2 ] = 0.99, P < 0.05). Estimation of PR was used to calculate the annual reproductive effort in P. margaritifera. Reproductive effort (%) was similar to those calculated for temperate species and showed a progressive increase with the age of pearl oyster, from 7 % in age-group I to 38 % in age-group III. This study showed that, in a fairly stable tropical environment such as the Takapoto lagoon, P. margaritifera is a multiple spawner, which uses an opportunistic reproductive strategy, allowing investment, all year around, of any surplus energy into gamete production. Surplus energy is ensured by the high pumping rates developed by this non-symbiotic bivalve to succeed in low seston conditions
Nouvelle architecture Doherty symétrique: Conception d'un amplificateur HEMT GaN 10 Watts bande X
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