572 research outputs found

    On Simulation of Manifold Indexed Fractional Gaussian Fields

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    To simulate fractional Brownian motion indexed by a manifold poses serious numerical problems: storage, computing time and choice of an appropriate grid. We propose an effective and fast method, valid not only for fractional Brownian fields indexed by a manifold, but for any Gaussian fields indexed by a manifold. The performance of our method is illustrated with different manifolds (sphere, hyperboloid).

    Alien Registration- Lacroix, Jacques J. (Saco, York County)

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    https://digitalmaine.com/alien_docs/2638/thumbnail.jp

    Effect of the over-ageing treatment on the mechanical properties of AA2024 aluminum alloy.

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    The evolution of the hardness of the over-ageing AA2024 alloy scale was followed by measurements of Vickers hardness. The nanoindentation is adapted to the determination of elastoplastic properties (hardness and Young’s modulus) of the matrix and also of coarse intermetallic precipitates. Influence of the artificial over-ageing time to hardness and to mechanical properties as the local scale was investigated

    ¿Qué hay de nuevo en la comunicación? = Is there something new in communication?

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    Resumen: Encontramos aquí una breve síntesis sobre parte de los descubrimientos realizados por el Dr. Lucas Derks, plasmadas en lo que él denominó como Modelo del Panorama Social, y sus efectos sobre la comunicación, las relaciones y la psicología humanas. Comienza con una introducción al concepto de espacio mental creado por el lingüista e investigador francés Fauconnier, y luego continúa mostrando como el Dr. Derks adoptó este concepto para la creación del modelo mencionado, dándonos una comprensión nueva sobre la forma en que funciona la comunicación humana. Desde esta perspectiva se abren nuevos caminos, dado que su aplicación es útil y práctica tanto a nivel diagnóstico como a nivel de herramienta de intervención (terapéutica o de coaching) para armonizar relaciones sociales.Palabras clave: Comunicación, Panorama Social, Modelo, Psicología, Espacio Mental.Abstract: We will find here a short review of part of Dr. Lucas Derks discoverings, captured in his so called Social Panorama Model, and their effects on human communication, realtionships and psychology. It starts with an introduction to the mental space concept created by the french linguist and researcher Fauconnier, and continues showing us how Dr. Derks adopted this concept to develope his above mentioned model, giving us a new insight to the way on how human communication works. From this perspective we will find new paths to go on, as the application is useful for both diagnostics and as intervention tool to harmonize social relations.Keywords: Communication, Social Panorama, Model, Psychology,  Mental Space

    On Simulation of Manifold Indexed Fractional Gaussian Fields

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    To simulate fractional Brownian motion indexed by a manifold poses serious numerical problems: storage, computing time and choice of an appropriate grid. We propose an effective and fast method, valid not only for fractional Brownian fields indexed by a manifold, but for any Gaussian fields indexed by a manifold. The performance of our method is illustrated with different manifolds (sphere, hyperboloid)

    On Fractional Gaussian Random Fields Simulations

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    To simulate Gaussian fields poses serious numerical problems: storage and computing time. The midpoint displacement method is often used for simulating the fractional Brownian fields because it is fast. We propose an effective and fast method, valid not only for fractional Brownian fields, but for any Gaussian fields. First, our method is compared with midpoint for fractional Brownian fields. Second, the performance of our method is illustrated by simulating several Gaussian fields. The software FieldSim is an R package developed in R and C and that implements the procedures on which this paper focuses

    Study of the influence of the artificial ageing temperature on the AA2024 alloy microstructure

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    For the last 30 years, AA2024 aluminum alloy was very used as structural material in the aerospace industry due to its low density and good mechanical strength. The phenomenon of precipitation hardening in aluminum alloys takes place at relatively low temperature and induces the precipitation of intermetallic particles composed of the main alloying elements i.e., copper and magnesium. The fundamental stage of the age-hardening process consists in the acceleration of the decomposition phenomenon of the supersaturated solid solution, resulting in the coarse intermetallic particle precipitation; stage where the mechanical properties reaches the maximum values, but at the cost of a low corrosion resistance. In this paper, the AA2024 alloy microstructure was studied during the over-ageing process. The over-ageing treatment (T7) is supposed to stabilize the microstructure and the mechanical properties to improve the corrosion resistance. The over-ageing treatment consists in a solution treatment at 495±5°C for 1 hour, quenched into cold water and artificial aged. Three different artificial ageing temperatures were studied: 150°C, 175°C and 190°C. The mechanical properties modifications were followed by Vickers macrohardness measurements. The treatment duration for each temperature (36 days for 150°C, 50 hrs for 175°C and 24 hrs for 190°C) was determined by a given macrohardness reduction. To characterize the over-aged AA2024 alloy microstructure, a statistical analysis of the surface fraction and surface density of intermetallic particles was made. The intermetallic particle dimension distribution, depending on the over-ageing temperature, was also observed. To do so, scanning electron microscope observations were carried out and image analyses were performed from backscattered electron images

    Application of Kelvin probe Force Microscopy (KFM) to evidence localized corrosion of over-aged aeronautical 2024 aluminum alloy

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    The 2xxx serie aluminum alloys are characterized by good mechanical performances and low density, however they are susceptible to different forms of localized corrosion: pitting corrosion, intergranular corrosion and stress corrosion cracking. The 2024-T351 aluminum alloy is used in the aircraft industry for numerous applications such as fuselage and door skin. Corrosion damage of the material is also very detrimental for the structural integrity of the aircraft. The presence of coarse intermetallic particles, with a heterogeneous size distribution was found to be responsible for the 2024 susceptibility to localized corrosion. These particles are generally the cause of initiation sites. Presence of micro-defects in the oxide film upon coarse intermetallic particles and the galvanic coupling with the matrix contribute to the development of pitting corrosion. The over-ageing treatment (T7) is supposed to stabilize the microstructure and the mechanical properties to improve the corrosion resistance. The 2024 alloy microstructure after the T7 heat treatment remains very complex. The 2024 alloy corrosion behavior was studied in the over-ageing state for three different temperatures (150, 175 and 190 °C). During the corrosion tests in chloride-containing environment, the behavior of coarse intermetallic particles was found to be different. Thus, the 2024 samples suffer a gradual attack upon S-Al2CuMg particles and finally Al(Cu,Mn,Fe,Si) particles. The corrosion damage was studied by Atomic Force Microscopy (AFM) and Kelvin probe Force Microscopy (KFM). This technique allows simultaneous topographical and electric potential mapping to be obtained. This latest potential was shown to be correlated to the corrosion potential of the 2024 alloy. This study focuses on the variation of the KFM potential of the coarse intermetallic particles and the matrix for the over-ageing conditions (T7). Observations using optical microscope and AFM were also performed to obtain the corrosion rate for each condition. The corrosion rate was correlated to the chemical composition variation of the particles obtained by scanning electron microscope observations and EDS analyses

    Techniques informatiques pour la cartographie physique de genome humain

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    Projet ICSLARésumé disponible dans le fichier PD

    N-Phenyl-N'-(2-chloroethyl)urea analogues of combretastatin A-4: Is the N-phenyl-N'-(2-chloroethyl)urea pharmacophore mimicking the trimethoxy phenyl moiety ?

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    A series of novel N-phenyl-N'-(2-chloroethyl)urea derivatives potentially mimicking the structure of combretastatin A-4 were synthesized and tested for their cell growth inhibition and their binding to the colchicine-binding site of beta-tubulin. Compounds 2a, 3a, and 3b were found to inhibit cell growth at the micromolar level on four human tumor cell lines. Flow cytometric analysis indicates that the new compounds act as antimitotics and arrest the cell cycle in G(2)/M phase. Covalent binding of 2a, 3a, and 3b to the colchicine-binding site of beta-tubulin was confirmed also using SDS-PAGE and competition assays
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