9 research outputs found
The ages and stages questionnaire and neurodevelopmental impairment in two-year-old preterm-born children
Objective: To test the ability of the Ages and Stages Questionnaire, Third Edition (ASQ3) to help identify or exclude neurodevelopmental impairment (NDI) in very preterm-born children at the corrected age of two. Methods: We studied the test results of 224 children, born a
Irradiance levels of phototherapy devices : A national study in Dutch neonatal intensive care units
Objective: The objective of this study is to determine whether irradiance levels of phototherapy (PT) devices in Dutch neonatal intensive care units (NICUs) increased between 2008 and 2013. Study Design: Irradiance of all types of PT devices, used in combination with incubators, was measured with a Dale 40 Radiometer (Fluke Biomedical, Everett, WA, USA) in all 10 Dutch NICUs. Results: Irradiance increased in seven NICUs. Median (range) irradiance increased from 9.7 (4.3-32.6) to 16.4 (6.8-41) ÎŒW cm-2 nm-1 for 24 overhead devices (P=0.004) and from 6.8 (0.8-15.6) to 22.3 (1.1-36.3) ÎŒW cm-2 nm-1 for 12 underneath devices (P=0.014). Five light-emitting diode (LED)-based devices were used in 2013 and one in 2008. The mean distance between overhead PT device and infant decreased by âŒ9 cm (P<0.001). Significantly more devices delivered minimal (10 ÎŒW cm-2 nm-1) recommended irradiance levels (80 vs âŒ45%; P=0.002). Conclusion: Irradiance of PT devices still varies, but has markedly improved since 2008 due to shorter distances between PT device and infant, and introduction of better performing LED-based devices
Characteristics of the study sample.
<p>Data are expressed as mean ± SD and [range], or median and (25â75 percentile)</p><p>ASQ3: Ages and Stages Questionnaire, Third Edition</p><p>BSIDIII: Bayley Scales of Infant and Toddler Development, Third Edition</p><p>Characteristics of the study sample.</p
Flowchart with numbers of eligible and included children.
<p>ASQ3; Ages and Stages Questionnaire, Third Edition, time window 22â26 months corrected age. BSIDIII: Bayley Scales of Infant and Toddler Development, Third Edition, time window 21â30 months corrected age. NDI: Neurodevelopmental Impairment: BSIDIII cognitive score or composite motor score <70, bilateral blindness/deafness or cerebral palsy.</p
ROC curve for NDI with BSIDIII threshold< 70 versus ASQ3 total scores.
<p>Area under the curve 96% p<0.0001</p
ASQ3 total scores for children with No NDI and children with NDI.
<p>NDI with BSID threshold set at < 70. Incomplete BSIDIII scores due to CP or severe mental impairment were imputed at 50 and incomplete ASQ3 scores were imputed with 0 points per item without a valid score.**** <i>p</i>< 0.0001</p
Correlation between BSIDIII combined cognitive and composite motor scores and ASQ3 total scores.
<p>R square is 0.417, p<0.001. Incomplete BSID scores due to CP or severe mental impairment were imputed at 50 and incomplete ASQ scores were imputed with 0 points per item without a valid score.</p
ASQ3 failures and the domains for different NDI thresholds.
<p>Data are presented as numbers and percentages.</p><p>ASQ3: Ages and Stages Questionnaire, Third edition.</p><p>Failure ASQ3: a score of >2 SD below the mean score for the U.S. reference group on any domain</p><p>BSIDIII: Bayley Scales of Infant and Toddler Development, Third Edition.</p><p>NDI with BSIDIII<70: neurodevelopmental impairment with BSIDIII cognitive score or composite motor score of <70, bilateral blindness/deafness and/or cerebral palsy.</p><p>NDI with BSIDIII<80: neurodevelopmental impairment with BSIDIII cognitive score or composite motor score of <80, bilateral blindness/deafness and/or cerebral palsy.</p><p>NDI with BSIDIII<85: neurodevelopmental impairment with BSIDIII cognitive score or composite motor score of <85, bilateral blindness/deafness and/or cerebral palsy.</p><p>ASQ3 failures and the domains for different NDI thresholds.</p