Reciprocal peer dislike and psychosocial adjustment in childhood

Reciprocal peer dislike was examined as a predictor of school adjustment and social relationship quality. One hundred and fifty one (69 male and 74 female, Mage = 9.53, SDage = 1.87 years) children completed measures of school liking, loneliness, and friendship quality twice over three months. From ratings of the amount of time participants liked to spend with individual classmates, social network analyses were used to determine reciprocal peer dislike. Curvilinear regression analyses revealed that reciprocal peer dislike at Time 1 predicted changes in the children’s loneliness and friendship quality assessed as help, security, and closeness over three months. The findings support the conclusion that reciprocal peer dislike predicts aspects of school adjustment and social relationship qualities

Centrality in children's best friend networks: the role of social behaviour

Centrality is an indicator of an individual's relative importance within a social group. Predictors of centrality in best friendship networks were examined in 146 children (70 boys, 76 girls, Mage= 9.95). Children completed measures of social confidence, social desirability, friendship quality, school liking, and loneliness, and nominated their best friends from within their class at two time points, 3 months apart. Multigroup path analysis revealed gender differences in the antecedents of centrality. Social confidence, social desirability, and friendship quality predicted changes in the indicators of centrality in best friend networks over time. In boys’ social behaviour positively predicted changes in centrality whereas in girls’ social behaviour negatively predicted changes in centrality. Together, these findings suggest that some aspects of social behaviour are influential for centrality in best friend groups

Simulation-based equation of state of the hard disk fluid and prediction of higher-order virial coefficients

We present new molecular dynamics results for the pressure of the pure hard disk fluid up to the hexatic transition (about reduced density 0.9). The data combined with the known virial coefficients (up to $B_{10}$) are used to build an equation of state, to estimate higher-order virial coefficients, and also to obtain a better value of $B_{10}$. Finite size effects are discussed in detail. The ``van der Waals-like'' loop reported in literature in the vicinity of the fluid/hexatic transition is explained by suppressed density fluctuations in the canonical ensemble. The inflection point on the pressure-density dependence is predicted by the equation of state even if the hexatic phase simulation data are not considered.Comment: 9 pages, 3 figures, presented at The Seventh Liblice Conference on the Statistical Mechanics of Liquids (Lednice, Czech Republic, June 11--16, 2006

Does correction for guessing reduce students' performance on multiple-choice examinations? Yes? No? Sometimes?

Multiple-choice (MC) examinations are becoming increasingly popular in higher education because they can be used effectively to assess breadth of knowledge in large cohorts of students. This present research investigated Psychology students' performance on, and experiences of, MC examinations with and without correction for guessing. In Study 1, data were collected from two cohorts of students across three Psychology MC examinations. The results revealed that students scored higher, and left fewer questions unanswered, when there was no correction for guessing. Furthermore, when the correction for guessing was removed from the theory MC examination, students who were told there was no correction for guessing did better than those told there was a correction. In addition, there was limited evidence of gender differences, with female students performing significantly better on one MC examination than males. In Study 2, a further set of first-year Psychology students reported their experiences of correction for guessing on open-book and closed-book MC examinations. Students reported feeling less anxious and more confident on the open-book MC examination. The findings of both of these studies have implications for instructors deciding whether or not correction for guessing is appropriate, and for the advice to be given to students preparing for MC examinations

Examining the components of children's peer liking as antecedents of school adjustment

Children’s social interactions with their peers influence their psychosocial adjustment; consequently, the relationship between class-wide peer liking, same-gender peer liking, and school adjustment was explored in two age groups. Peer liking was analysed using the social relations model (SRM). In Study 1, 205 children (103 female and 102 male, Mage = 7.15, SD = 7 months) completed measures of peer liking and school adjustment, and teachers completed the Short-Form TRSSA. In Study 2, 197 children (98 female and 90 male, Mage = 9.87, SD = 5.9 months) completed measures of peer liking and school adjustment. Both studies yielded evidence of reciprocal liking and individual differences in the ratings of liking awarded to, and elicited from, both peer groups. Multigroup path analysis, with groups created according to gender, revealed that elements of liking predicted different aspects of school adjustment with some variation according to age and gender. Together, these findings suggest that the SRM can be used to examine peer liking and underscore the importance of children’s peers for school adjustment

Parental rearing style as a predictor of attachment and psychosocial adjustment during young adulthood

Parental rearing-styles are crucial for psychosocial adjustment both during childhood and adulthood. The current study examined whether: (a) parental rearing-styles predicted psychosocial adjustment in young-adulthood, (b) this relationship was mediated by attachment styles , and ( c ) gender differences occur in these relationships. Two hundred and forty (103 male and 132 female) university students completed measures assessing parental rearing-style , current attachment style, romantic relationship satisfaction, friendship quality, self-esteem, and social competence. Multigroup structural equation modelling, conducted separately by gender, revealed that parental rearing-style predicted psychosocial adjustment during young-adulthood. Further, there was also evidence of gender differences and that self-models and other-models of attachment mediated this relationship. Together, these findings reinforce the importance of perceived parental rearing-style for subsequent psychosocial adjustment

Adjustment of interaural-time-difference analysis to sound level

To localize low-frequency sound sources in azimuth, the binaural system compares the timing of sound waves at the two ears with microsecond precision. A similarly high precision is also seen in the binaural processing of the envelopes of high-frequency complex sounds. Both for low- and high-frequency sounds, interaural time difference (ITD) acuity is to a large extent independent of sound level. The mechanisms underlying this level-invariant extraction of ITDs by the binaural system are, however, only poorly understood. We use high-frequency pip trains with asymmetric and dichotic pip envelopes in a combined psychophysical, electrophysiological, and modeling approach. Although the dichotic envelopes cannot be physically matched in terms of ITD, the match produced perceptually by humans is very reliable, and it depends systematically on the overall sound level. These data are reflected in neural responses from the gerbil lateral superior olive and lateral lemniscus. The results are predicted in an existing temporal-integration model extended with a level-dependent threshold criterion. These data provide a very sensitive quantification of how the peripheral temporal code is conditioned for binaural analysis

Assessing the short-term outcomes of a community-based intervention for overweight and obese children: The MEND 5-7 programme

Objective The aim of this study was to report outcomes of the UK service level delivery of MEND (Mind,Exercise,Nutrition...Do it!) 5-7, a multicomponent, community-based, healthy lifestyle intervention designed for overweight and obese children aged 5–7 years and their families. Design Repeated measures. Setting Community venues at 37 locations across the UK. Participants 440 overweight or obese children (42% boys; mean age 6.1 years; body mass index (BMI) z-score 2.86) and their parents/carers participated in the intervention. Intervention MEND 5-7 is a 10-week, family-based, child weight-management intervention consisting of weekly group sessions. It includes positive parenting, active play, nutrition education and behaviour change strategies. The intervention is designed to be scalable and delivered by a range of health and social care professionals. Primary and secondary outcome measures The primary outcome was BMI z-score. Secondary outcome measures included BMI, waist circumference, waist circumference z-score, children's psychological symptoms, parenting self-efficacy, physical activity and sedentary behaviours and the proportion of parents and children eating five or more portions of fruit and vegetables. Results 274 (62%) children were measured preintervention and post-intervention (baseline; 10-weeks). Post-intervention, mean BMI and waist circumference decreased by 0.5 kg/m2 and 0.9 cm, while z-scores decreased by 0.20 and 0.20, respectively (p<0.0001). Improvements were found in children's psychological symptoms (−1.6 units, p<0.0001), parent self-efficacy (p<0.0001), physical activity (+2.9 h/week, p<0.01), sedentary activities (−4.1 h/week, p<0.0001) and the proportion of parents and children eating five or more portions of fruit and vegetables per day (both p<0.0001). Attendance at the 10 sessions was 73% with a 70% retention rate. Conclusions Participation in the MEND 5-7 programme was associated with beneficial changes in physical, behavioural and psychological outcomes for children with complete sets of measurement data, when implemented in UK community settings under service level conditions. Further investigation is warranted to establish if these findings are replicable under controlled conditions

GSplit LBI: Taming the Procedural Bias in Neuroimaging for Disease Prediction

In voxel-based neuroimage analysis, lesion features have been the main focus in disease prediction due to their interpretability with respect to the related diseases. However, we observe that there exists another type of features introduced during the preprocessing steps and we call them "\textbf{Procedural Bias}". Besides, such bias can be leveraged to improve classification accuracy. Nevertheless, most existing models suffer from either under-fit without considering procedural bias or poor interpretability without differentiating such bias from lesion ones. In this paper, a novel dual-task algorithm namely \emph{GSplit LBI} is proposed to resolve this problem. By introducing an augmented variable enforced to be structural sparsity with a variable splitting term, the estimators for prediction and selecting lesion features can be optimized separately and mutually monitored by each other following an iterative scheme. Empirical experiments have been evaluated on the Alzheimer's Disease Neuroimaging Initiative\thinspace(ADNI) database. The advantage of proposed model is verified by improved stability of selected lesion features and better classification results.Comment: Conditional Accepted by Miccai,201

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes

The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models of disrupted CNP and GC-B indicate a potential role in growth hormone secretion. In the current study, we investigate the molecular and pharmacological properties of the CNP/GC-B system in somatotrope lineage cells. Primary rat pituitary and GH3 somatolactotropes expressed functional GC-A and GC-B receptors that had similar EC50 properties in terms of cGMP production. Interestingly, GC-B signaling underwent rapid homologous desensitization in a protein phosphatase 2A (PP2A)-dependent manner. Chronic exposure to either CNP or ANP caused a significant down-regulation of both GC-A- and GC-B-dependent cGMP accumulation in a ligand-specific manner. However, this down-regulation was not accompanied by alterations in the sub-cellular localization of these receptors. Heterologous desensitization of GC-B signaling occurred in GH3 cells following exposure to either sphingosine-1-phosphate or thyrotrophin-releasing hormone (TRH). This heterologous desensitization was protein kinase C (PKC)-dependent, as pre-treatment with GF109203X prevented the effect of TRH on CNP/GC-B signaling. Collectively, these data indicate common and distinct properties of particulate guanylyl cyclase receptors in somatotropes and reveal that independent mechanisms of homologous and heterologous desensitization occur involving either PP2A or PKC. Guanylyl cyclase receptors thus represent potential novel therapeutic targets for treating growth-hormone-associated disorders