Distribution Systems of Insecticide-Treated Bed Nets for Malaria Control in Rural Burkina Faso: Cluster-Randomized Controlled Trial

BACKGROUND: Insecticide-impregnated bed nets (ITNs) have been shown to be a highly effective tool against malaria in the endemic regions of sub-Saharan Africa (SSA). There are however different opinions about the role of ITN social marketing and ITN free distribution in the roll-out of ITN programmes. The objective of this study was to evaluate the effects of free ITN distribution through antenatal care services in addition to an ITN social marketing programme in an area typical for rural SSA. METHODS: A cluster-randomised controlled ITN trial took place in the whole Kossi Province in north-western Burkina Faso, an area highly endemic for malaria. Twelve clusters were assigned to long-term ITN (Serena brand) social marketing plus free ITN (Serena brand) distribution to all pregnant women attending governmental antenatal care services (group A), and 13 clusters to ITN social marketing only (group B). The intervention took place during the rainy season of 2006 and thereafter. The trial was evaluated through a representative household survey at baseline and after one year. Serena ITN household ownership was the primary outcome measure. FINDINGS: A total of 1052 households were visited at baseline in February 2006 and 1050 at follow-up in February 2007. Overall Serena ITN household ownership increased from 16% to 28% over the study period, with a significantly higher increase in group A (13% to 35%) than in group B (18% to 23%) (p<0.001). INTERPRETATION: The free distribution of ITNs to pregnant women through governmental antenatal care services in addition to ITN social marketing substantially improved ITN household ownership in rural Burkina Faso. TRIAL REGISTRATION: Controlled-Trials.com ISRCTN07985309

A randomized controlled trial of a wearable technology-based intervention for increasing moderate to vigorous physical activity and reducing sedentary behavior in breast cancer survivors: The ACTIVATE Trial

Background: The benefits of an active lifestyle after a breast cancer diagnosis are well recognized, but the majority of survivors are insufficiently active. The ACTIVATE Trial examined the efficacy of an intervention (use of the Garmin Vivofit 2 activity monitor coupled with a behavioral feedback and goal-setting session and 5 telephone-delivered health coaching sessions) to increase moderate to vigorous physical activity (MVPA) and reduce sedentary behavior in breast cancer survivors. Methods: This randomized controlled trial recruited 83 inactive, postmenopausal women diagnosed with stage I-III breast cancer who had completed primary treatment. Participants were randomly assigned to the intervention group or to the control group, and the intervention was delivered over a 12-week period. MVPA and sedentary behavior were measured with Actigraph and activPAL accelerometers at baseline (T1) and at the end of the intervention (T2). Results: Retention in the trial was high, with 80 (96%) of participants completing T2 data collection. At T2, there was a significant between-group difference in MVPA (69\ua0min/wk; 95% CI\ua0=\ua022-116) favoring the intervention group. The trial resulted in a statistically significant decrease in both total sitting time and prolonged bouts (≥20\ua0min) of sitting, with between-group reductions of 37\ua0min/d (95% CI\ua0=\ua0−72 to −2) and 42\ua0min/d (95% CI\ua0=\ua0−83 to −2), respectively, favoring the intervention group. Conclusion: Results from the ACTIVATE Trial suggest that the use of wearable technology presents an inexpensive and scalable opportunity to facilitate more active lifestyles for cancer survivors. Whether or not such wearable technology-based interventions can create sustainable behavioral change should be the subject of future research

Life cycle assessment of integrated seawater agriculture in the Arabian (Persian) Gulf as a potential food and aviation biofuel resource

Purpose: Prospective evaluation of the lifecycle impacts of aviation biofuel production in Abu Dhabi, UAE based on a production system that integrates aquaculture, saltwater agriculture, and mangrove silviculture, termed an Integrated Seawater Energy Agriculture System (ISEAS) in order to investigate its energetic and environmental potential compared to conventional fuels. Methods: We compare the hydroprocessed renewable jet fuel (HRJ) produced from ISEAS against fossil jet fuel using a life cycle assessment (LCA) methodology. Based on a detailed description of the production process, we use data from a wide-ranging literature review and experimental results from the specific location to make informed assumptions for the range of the process inputs and yields. We then analyze several process configuration scenarios with different ranges. Results and discussion: ISEAS can produce aviation biofuels, electricity, and food while afforesting coastal desert land, acting as a long-term sink for carbon, minimizing freshwater consumption, and having beneficial land use impacts when compared to fossil jet fuel production. Based on a sensitivity analysis, we show that ISEAS HRJ emits 38 to 68% less greenhouse gases than fossil jet fuel and yields an overall positive net energy balance under all scenarios except one with an extensive use of desalinated water. Conclusions: ISEAS offers a promising pathway for integrating aquaculture and seawater agriculture in arid regions. It is essentially a process to sustainably augment aquaculture-based products by using its waste as a biofuel resource. Achieving positive emissions results depend critically on minimizing freshwater use, maximizing biomass yield and to a lesser extent the performance of biomass gasification. , Springer-Verlag Berlin Heidelberg.Acknowledgments: This work was supported by a Boeing Company grant and the Sustainable Bioengy Research Consortium of Masdar Institute. We acknowledge the contribution of Dr. Michael Timmons of Cornell Univesity and Edward P. Glenn of the University of Arizona for providing insights on halophyte cultivation.Scopu