6,022 research outputs found
Double lenses
The analysis of the shear induced by a single cluster on the images of a
large number of background galaxies is all centered around the curl-free
character of a well-known vector field that can be derived from the data. Such
basic property breaks down when the source galaxies happen to be observed
through two clusters at different redshifts, partially aligned along the line
of sight. In this paper we address the study of double lenses and obtain five
main results. (i) First we generalize the procedure to extract the available
information, contained in the observed shear field, from the case of a single
lens to that of a double lens. (ii) Then we evaluate the possibility of
detecting the signature of double lensing given the known properties of the
distribution of clusters of galaxies. (iii) As a different astrophysical
application, we demonstrate how the method can be used to detect the presence
of a dark cluster that might happen to be partially aligned with a bright
cluster studied in terms of statistical lensing. (iv) In addition, we show that
the redshift distribution of the source galaxies, which in principle might also
contribute to break the curl-free character of the shear field, actually
produces systematic effects typically two orders of magnitude smaller than the
double lensing effects we are focusing on. (v) Remarkably, a discussion of
relevant contributions to the noise of the shear measurement has brought up an
intrinsic limitation of weak lensing analyses, since one specific contribution,
associated with the presence of a non-vanishing two-galaxy correlation
function, turns out not to decrease with the density of source galaxies (and
thus with the depth of the observations).Comment: 40 pages, 15 figures. Accepted for publication in ApJ main journa
Growth and instability of a laminar plume in a strongly stratified environment
Experimental studies of laminar plumes descending under gravity into stably stratified environments have shown the existence of a critical injection velocity beyond which the plume exhibits a bifurcation to a coiling instability in three dimensions or a sinuous instability in a Hele-Shaw flow. In addition, flow visualization has shown that, prior to the onset of the instability, a stable base flow is established in which the plume penetrates to a depth significantly smaller than the neutral buoyancy depth. Moreover, the fresh water that is viscously entrained by the plume recirculates within a ‘conduit’ whose boundary with the background stratification appears sharp. Beyond the bifurcation, the buckling plume takes the form of a travelling wave of varying amplitude, confined within the conduit, which disappears at the penetration depth. To determine the mechanisms underlying these complex phenomena, which take place at a strikingly low Reynolds number but a high Schmidt number, we study here a two-dimensional arrangement, as it is perhaps the simplest system which possesses all the key experimental features. Through a combination of numerical and analytical approaches, a scaling law is found for the plume’s penetration depth within the base flow (i.e. the flow where the instability is either absent or artificially suppressed), and the horizontal cross-stream velocity and concentration profile outside the plume are determined from an asymptotic analysis of a simplified model. Direct numerical simulations show that, with increasing flow rate, a sinuous global mode is destabilized giving rise to the self-sustained oscillations as in the experiment. The sinuous instability is shown to be a consequence of the baroclinic generation of vorticity, due to the strong horizontal gradients at the edge of the conduit, a mechanism that is relevant even at very low Reynolds numbers. Despite the strength of this instability, the penetration depth is not significantly affected by it, instead being determined by the properties of the plume in the vicinity of the source. This scenario is confirmed by a local stability analysis. A finite region of local absolute instability is found near the source for sinuous modes prior to the onset of the global instability. Sufficiently far from the source the flow is locally stable. Near the onset of the global instability, varicose modes are also found to be locally, but only convectively, unstable
Iginio Tansini revisited
The origin of the muscolocutaneous latissimus dorsi flap dates back to 1906 when Igino Tansini, an Italian surgeon, described a procedure to reconstruct the mastectomy defect. After a detailed study of Tansini's original description and drawings, new insights about the pedicle of its compound flap have been found, showing that it has the same pedicle of the scapular flap. In the end, Tansini's flap should be more correctly considered as a compound musculocutaneous scapular flap
Numerical simulations challenged on the prediction of massive subhalo abundance in galaxy clusters: the case of Abell 2142
In this Letter we compare the abundance of member galaxies of a rich, nearby
() galaxy cluster, Abell 2142, with that of halos of comparable virial
mass extracted from sets of state-of-the-art numerical simulations, both
collisionless at different resolutions and with the inclusion of baryonic
physics in the form of cooling, star formation, and feedback by active galactic
nuclei. We also use two semi-analytical models to account for the presence of
orphan galaxies. The photometric and spectroscopic information, taken from the
Sloan Digital Sky Survey Data Release 12 (SDSS DR12) database, allows us to
estimate the stellar velocity dispersion of member galaxies of Abell 2142. This
quantity is used as proxy for the total mass of secure cluster members and is
properly compared with that of subhalos in simulations. We find that simulated
halos have a statistically significant ( sigma confidence level)
smaller amount of massive (circular velocity above )
subhalos, even before accounting for the possible incompleteness of
observations. These results corroborate the findings from a recent strong
lensing study of the Hubble Frontier Fields galaxy cluster MACS J0416
\citep{grillo2015} and suggest that the observed difference is already present
at the level of dark matter (DM) subhalos and is not solved by introducing
baryonic physics. A deeper understanding of this discrepancy between
observations and simulations will provide valuable insights into the impact of
the physical properties of DM particles and the effect of baryons on the
formation and evolution of cosmological structures.Comment: 8 pages, 2 figures. Modified to match the version published in ApJ
Phase Rotation, Cooling And Acceleration Of Muon Beams: A Comparison Of Different Approaches
Experimental and theoretical activities are underway at CERN with the aim of
examining the feasibility of a very-high-flux neutrino source. In the present
scheme, a high-power proton beam (some 4 MW) bombards a target where pions are
produced. The pions are collected and decay to muons under controlled optical
condition. The muons are cooled and accelerated to a final energy of 50 GeV
before being injected into a decay ring where they decay under well-defined
conditions of energy and emittance.
We present the most challenging parts of the whole scenario, the muon
capture, the ionisation-cooling and the first stage of the muon acceleration.
Different schemes, their performance and the technical challenges are compared.Comment: LINAC 2000 CONFERENCE, paper ID No. THC1
Non-deterministic Gates for Photonic Single Rail Quantum Logic
We discuss techniques for producing, manipulating and measureing qubits
encoded optically as vacuum and single photon states. We show that a universal
set of non-deterministic gates can be constructed using linear optics and
photon counting. We investigate the efficacy of a test gate given realistic
detector efficiencies.Comment: 8 pages, 6 figure
Thyroid nodules treated with percutaneous radiofrequency thermal ablation: a comparative study
Percutaneous radiofrequency thermal ablation (RTA) was reported as an effective tool for the management of thyroid nodules (TNs). The aim of this study was to investigate the effects of RTA and to establish whether they were treatment-related by comparison with a matched, untreated control group
Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44.
Sulfatase modifying factor 1 (SUMF1) encodes for the formylglicine generating enzyme, which activates sulfatases by modifying a key cysteine residue within their catalytic domains. SUMF1 is mutated in patients affected by multiple sulfatase deficiency, a rare recessive disorder in which all sulfatase activities are impaired. Despite the absence of canonical retention/retrieval signals, SUMF1 is largely retained in the endoplasmic reticulum (ER), where it exerts its enzymatic activity on nascent sulfatases. Part of SUMF1 is secreted and paracrinally taken up by distant cells. Here we show that SUMF1 interacts with protein disulfide isomerase (PDI) and ERp44, two thioredoxin family members residing in the early secretory pathway, and with ERGIC-53, a lectin that shuttles between the ER and the Golgi. Functional assays reveal that these interactions are crucial for controlling SUMF1 traffic and function. PDI couples SUMF1 retention and activation in the ER. ERGIC-53 and ERp44 act downstream, favoring SUMF1 export from and retrieval to the ER, respectively. Silencing ERGIC-53 causes proteasomal degradation of SUMF1, while down-regulating ERp44 promotes its secretion. When over-expressed, each of three interactors favors intracellular accumulation. Our results reveal a multistep control of SUMF1 trafficking, with sequential interactions dynamically determining ER localization, activity and secretion
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