Balance and aerobic capacity of independent elderly: a longitudinal cohort study

OBJETIVO: Avaliar a variação da capacidade aeróbica e do equilíbrio postural em idosos independentes por um período de três anos. MÉTODOS: A capacidade aeróbica dos voluntários foi avaliada por meio do Teste de Caminhada de 6 minutos (TC6); o equilíbrio postural, por meio da Escala de Equilíbrio de Berg (EEB); o número de quedas foi registrado por autorrelato e o nível de atividade física, pelo Questionário Internacional de Atividade Física (IPAQ - versão longa). As avaliações realizadas em 2008 foram comparadas às realizadas em 2005. RESULTADOS: Não houve diferença na pontuação da EEB e no número de quedas dos idosos avaliados (p>0,05). Houve diminuição da distância percorrida entre as duas avaliações, sendo que os voluntários percorreram 52,46±8,4 metros a menos na segunda avaliação. O IPAQ evidenciou aumento de indivíduos considerados ativos na segunda avaliação (83,3%). CONCLUSÃO: O presente estudo demonstrou que o equilíbrio postural, avaliado pela EEB, não se alterou nos idosos independentes e ativos no período de três anos. Nesse mesmo momento, observou-se uma redução da distância percorrida, avaliada pelo TC6.OBJECTIVE: To evaluate the variation in aerobic capacity and postural balance of independents elderly for a period of three years. METHODS: The aerobic capacity of the volunteers was assessed using a six minutes walk test (6MWT), the postural balance was assessed using the Berg Balance Scale (BBS), the number of falls was self-reported and physical activity level was assessed using the International Physical Activity Questionnaire (IPAQ - long version). Evaluations undertaken in 2008 were compared to those performed in 2005. RESULTS: There were no differences in balance and number of falls between 2008 and 2005 (p>0.05). There was a decrease in aerobic capacity over time of 52.46±8.4 meters walked. The IPAQ showed an increase in physical activity on the second evaluation (83.3%). CONCLUSION: The present study demonstrated that balance, evaluated using BBS did not change in the active independent elderly for a period of three years. However, over the there year period there was a decrease in aerobic capacity evaluated using the 6MWT

Delirium

Delirium, also known as acute confusional state is a cognitive impairment defined by acute onset and fluctuating course, disturbance of consciousness, attention, orientation, memory, thought, perception and behavior. It is an increasingly common condition among hospitalized patients and more frequent in, elderly and debilitated patients. It is a medical emergency, already proven higher death rates, longer hospitalization and higher rates of institutionalization due the occurrence of delirium. The pathophysiologic mechanism is not yet well established, with the change in neurotransmission most probably involved. Management of patients should include identification of risk factors and precipitants, with appropriate interventions aimed at each resolution. It is presented by altered level of consciousness, attention deficit and other disorders of cognition, which may present as hyperactive, hypoactive, or mixed. Although well defined, several times delirium goes unrecognized by health professionals. The main measure in addressing delirium is prevention, with institutional measures required as well as training of health professionals. Non-pharmacological treatment consists of measures to prevent the factors responsible for the development of delirium , and is the first option in the initial approach. Pharmacological  treatment is reserved for patients with major upheaval, with the risk of physical trauma, and presenting no response to non-pharmacological measures. For the frequency and importance as a prognostic factor, delirium should be approached systematically, with flowcharting care and defining standardized measures for each institution. Delirium também conhecido como estado confusional agudo é uma alteração cognitiva definida por início agudo, curso flutuante, distúrbios da consciência, atenção, orientação, memória, pensamento, percepção e comportamento. É condição cada vez mais comum entre pacientes hospitalizados  e acomete, preferencialmente, pacientes idosos e debilitados. Trata-se de emergência médica, já sendo comprovadas maiores taxas de mortalidade, maior tempo de internação e maiores índices de institucionalização quando do episódio de delirium.O mecanismo fisiopatológico ainda não está bem definido, sendo a alteração na neurotransmissão o mecanismo mais provável. A abordagem do paciente deve incluir a identificação de fatores predisponentes e precipitantes, com intervenções adequadas a cada um visando à resolução do quadro. Apresenta-se por alteração do nível de consciência, déficit de atenção e outros distúrbios da cognição, podendo se apresentar na forma hiperativa, hipoativa ou mista. Apesar de já estar bem definido, por diversas vezes passa despercebido aos profissionais de saúde. A principal medida na abordagem de delirium é a prevenção, e são necessárias medidas institucionais e treinamento dos profissionais de saúde. O tratamento não-farmacológico consiste em medidas que evitem os fatores responsáveis pelo desenvolvimento do delirium , sendo a primeira opção na abordagem inicial. O tratamento farmacológico se reserva aos pacientes com agitação importante, com risco de trauma físico, e que não apresentem resposta às medidas não-farmacológicas. Por  sua frequência e importância como fator prognóstico, o delirium deve ser abordado de forma sistematizada, com a elaboração de fluxogramas de atendimento e definição de medidas uniformizadas para cada instituição.   

Cuidados paliativos em enfermaria de clínica médica

Chronic progressive incurable illness is a major cause of disability, distress, suffering, and, ultimately, death. This is true for many causes of cancer, progressive neurologic disorders, AIDS, and other disorders of vital organs. When cure in not possible, as often it is not, the relief of suffering is the cardinal goal of medicine. The knowledge and the acceptance of this axiom is the heart of the philosophy, science, and practice of palliative medicine.Doença crônica degenerativa incurável é uma causa maior de disfunção, aflição, sofrimento, e, por último, morte. Isso é fato para várias causas de câncer, doenças neurológicas, AIDS e outras disfunções de órgãos vitais. Quando a cura não é possível, como frequentemente não é, o alívio do sofrimento torna-se o principal objetivo da medicina. O conhecimento e a aceitação desse axioma é o cerne da filosofia, ciência e prática da medicina paliativa

Treatment adherence and blood pressure control in older individuals with hypertension

FUNDAMENTO: A não adesão ao tratamento tem sido identificada como a causa principal da Pressão Arterial (PA) não controlada, e pode representar um risco maior em idosos. OBJETIVO: O objetivo deste estudo foi avaliar e comparar a taxa de adesão ao tratamento da hipertensão arterial por diferentes métodos, para estimar a taxa de controle da PA, e observar se há uma associação entre controle da pressão arterial e adesão. MÉTODOS: A adesão ao tratamento foi avaliada em pacientes idosos com hipertensão, acompanhados pelo serviço público de saúde, por meio de quatro métodos, incluindo o teste de Morisky-Green (referência), o questionário sobre atitudes referentes à ingestão de medicação (AMI), uma avaliação da adesão por parte do enfermeiro em consultório (AEC), e avaliação domiciliar da adesão (ADA). A ingestão de sal foi estimada pela excreção urinária de sódio de 24 horas. O controle da pressão arterial foi avaliado pelo monitorização ambulatorial da pressão arterial na vigília. RESULTADOS: A concordância entre o teste de Morisky-Green e o AMI (Kappa = 0,27) ou a AEC (Kappa = 0,05) foi pobre. Houve uma concordância moderada entre o teste de Morisky-Green e a ADA. Oitenta por cento tinham a PA controlada, incluindo 42% com efeito do jaleco branco. O grupo com menor excreção de sal relatou evitar o consumo de sal mais vezes (p < 0,001) e também teve maior adesão ao medicamento (p < 0,001) do que o grupo com maior de excreção de sal. CONCLUSÃO: Os testes avaliados não apresentaram boa concordância com o teste de Morisky-Green. A adesão ao tratamento da hipertensão foi baixa; no entanto, houve uma elevada taxa de controle da pressão arterial, quando os sujeitos com o efeito do jaleco branco foram incluídos na análise

Relationship between changes in insulin sensitivity and associated cardiovascular disease risk factors in thiazolidinedione-treated, insulin-resistant, nondiabetic individuals: pioglitazone versus rosiglitazone

This study compared the effects of administering rosiglitazone (RSG) vs pioglitazone (PIO) oil cardiovascular disease risk factors in insulin-resistant. nondiabetic individuals with no apparent disease. Twenty-two nondiabetic, apparently healthy individuals, classified as being insulin resistant oil the basis of a steady-state plasma glucose concentration of at least 10 mmol/L during the insulin suppression test, were treated with either RSG or 1110 for 3 months. Measurements were made before and after drug treatment of weight; blood pressure; fasting and daylong glucose, insulin, and free fatty acid (FFA) levels; and lipid and lipoprotein concentrations. Insulin sensitivity (steady-state plasma glucose concentration) significantly improved in both treatment groups, associated with significant decreases in daylong plasma concentrations of glucose, insulin, and FFA. Diastolic blood pressure fell somewhat in both groups, and this change reached significance in those receiving PIO. Improvement in lipid metabolism was confined to the PIO-treated group, signified by a significant decrease in plasma triglyceride concentration, whereas triglyceride concentration did not decline in the RSG-treated group, and these individuals also had increases in total (P = .047) and low-density lipoprotein cholesterol (P = .07). In conclusion, RSG and PIO appear to have comparable abilities to improve insulin sensitivity and lower daylong glucose, insulin, and FFA concentrations in nondiabetic, insulin-resistant individuals. However, despite these similarities, their effects on lipoprotein metabolism seem to be quite different, with beneficial effects confined to PIO-treated individuals. (C) 2009 Elsevier Inc. All rights reserved.National Center for Research Resources, National Institutes of Health (NIH)[M01 RR-000070]CAPES[1306-07-3]Glaxo-SmithKline PharmaceuticalsTakeda Pharmaceutical

Presión arterial obtenida por los métodos oscilométrico y auscultatorio antes y tras ejercicio en adultos mayores

FUNDAMENTO: Diferentes métodos de medida da pressão arterial (PA) têm sido utilizados em avaliações clínicas e científicas. Entretanto, os métodos empregados apresentam limitações e particularidades a serem consideradas. OBJETIVO: Avaliar se valores semelhantes de PA são obtidos em idosos hipertensos submetidos ao exercício resistido, ao usarem-se os métodos oscilométrico (Omron-HEM-431) e auscultatório (esfigmomanômetro de mercúrio). MÉTODOS: Dezesseis idosos hipertensos realizaram três sessões experimentais randomizadas com diferentes volumes: as sessões controle (C: 40 minutos), exercício 1 (E1: 20 minutos) e exercício 2 (E2: 40 minutos). A PA foi medida simultaneamente pelos dois métodos, a cada 5 minutos durante 20 minutos antes das sessões e durante 60 minutos após as mesmas. RESULTADOS: No período pré-intervenção houve boa concordância entre as medidas da pressão arterial sistólica (PAS) e diastólica (PAD) obtidas pelos dois métodos, havendo também elevada concordância geral após as sessões (Coeficiente de Lin = 0,82 e 0,81, respectivamente). Houve melhor concordância da PAD após a sessão controle do que após as sessões de exercício. A diferença entre as medidas obtidas entre os dois métodos foi maior para a PAD do que para a PAS após todas as sessões (p < 0.001). Independentemente do método, pode-se verificar a queda da PAS e da PAD que ocorreram nos primeiros 60 minutos após a realização dos exercícios. CONCLUSÃO: Os métodos auscultatório e oscilométrico foram concordantes antes e após as sessões controle e de exercícios, havendo, no entanto, maiores diferenças da PAD do que da PAS, sendo esta última muito semelhante entre métodos.BACKGROUND: Different methods of measuring blood pressure (BP) have been used in clinical and scientific evaluations. However, the methods employed have constraints and peculiarities to be considered. OBJECTIVE: To evaluate whether similar BP values are obtained in elderly hypertensive patients undergoing resistance exercises when using the oscillometric (Omron-HEM-431) and auscultatory methods (mercury sphygmomanometer). METHODS: Sixteen elderly hypertensive patients underwent three randomized experimental sessions with different volumes: control (C: 40 minutes), exercise 1 (E1: 20 minutes) and exercise 2 sessions (E2: 40 minutes). BP was measured simultaneously through two methods every 5 minutes for 20 minutes before the sessions and during 60 minutes after them. RESULTS: In the pre-intervention period, there was concordance between systolic blood pressure (SBP) and diastolic blood pressure measurements (DBP) obtained through two methods, as well as a high overall concordance after the sessions (Lin's concordance coefficient = 0.82 and 0.81, respectively). Greater concordance in DBP was found after the control session than after exercise sessions. The difference between the measurements obtained between the two methods was greater for DBP than for SBP after all sessions (p < 0.001). Regardless of the method, SBP and DBP fell in the first 60 minutes after the exercises. CONCLUSION: The auscultatory and oscillometric methods were consistent before and after the control and exercise sessions. However, greater differences were found in DBP than in SBP. The latter was very similar between methods.FUNDAMENTO: Diferentes métodos de medición de la presión arterial (PA) se vienen utilizando en evaluaciones clínicas y científicas. Sin embargo, los métodos empleados presentan limitaciones y particularidades a tener en cuenta. OBJETIVO: Evaluar si valores semejantes de PA se obtienen en adultos mayores hipertensos sometidos al ejercicio resistido, al emplearse los métodos oscilométrico (Omron-HEM-431) y auscultatorio (esfigmomanómetro de mercurio). MÉTODOS: Dieciséis adultos mayores hipertensos participaron en tres sesiones experimentales randomizadas con diferentes volúmenes: las sesiones control (C: 40 minutos), ejercicio 1 (E1: 20 minutos) y ejercicio 2 (E2: 40 minutos). La PA se midió simultáneamente por los dos métodos, a cada 5 minutos durante 20 minutos antes de las sesiones y durante 60 minutos tras las mismas. RESULTADOS: En el período pre intervención hubo una buena concordancia entre las mediciones de la presión arterial sistólica (PAS) y diastólica (PAD) obtenidas por los dos métodos, habiendo también elevada concordancia general tras las sesiones (Coeficiente de Lin = 0,82 y 0,81, respectivamente). Hubo mejor concordancia de la PAD tras la sesión control que después de las sesiones de ejercicio. La diferencia entre las medidas obtenidas entre los dos métodos fue mayor para la PAD que para la PAS tras todas las sesiones (p < 0.001). Independientemente del método, se puede verificar el descenso de la PAS y de la PAD que se produjeron en los primeros 60 minutos después de la realización de los ejercicios. CONCLUSIÓN: Los métodos auscultatorio y oscilométrico fueron concordantes antes y después de las sesiones control y de ejercicios, habiendo, sin embargo, mayores diferencias de la PAD que de la PAS, con esta última muy semejante entre métodos.USP - FAEPA-HCFMR

Prevalence of Insulin Resistance and Related Risk Factors for Cardiovascular Disease in Patients With Essential Hypertension

BACKGROUND There is evidence that the subgroup of patients with essential hypertension who are also insulin resistant is at increased risk of cardiovascular disease (CVD). We are unaware of the frequency of insulin resistance in patients with essential hypertension as well as the CVD risk in this subgroup of patients. This analysis was aimed at providing the prevalence of insulin resistance and associated CVD risk factors in treated and untreated patients with essential hypertension. METHODS The study population consisted of 126 patients with hypertension: 56 untreated and 70 in a stable treatment program. Body mass index (BMI), blood pressure, plasma glucose and insulin responses to an oral glucose challenge, lipid and lipoprotein concentrations, and steady-state plasma glucose (SSPG) concentration during the insulin suppression test were measured. Insulin resistance was defined operationally as a SSPG concentration >180 mg/dl. RESULTS Demographic characteristics and metabolic CVD risk factors were comparable in both groups, with 30-50% of both treated and untreated patients having abnormalities of all risk factors measured. Approximately 50% of patients met the criteria for insulin resistance in both groups, and the prevalence of abnormal CVD risk factors in this group was increased two to threefold as compared to the other half of the subjects. CONCLUSIONS Approximately 50% of patients with essential hypertension, both treated and untreated, appear to be insulin resistant, and CVD risk factors are greatly accentuated in this subset of patients.National Institutes of Health (NIH)[RR-00070]CAPES (Research Funding Agency of the Brazilian Ministry of Education)[1306-07-3

THE EFFECT OF DIFFERENT VOLUMES OF ACUTE RESISTANCE EXERCISE ON ELDERLY INDIVIDUALS WITH TREATED HYPERTENSION

Scher, LML, Ferriolli, E, Moriguti, JC, Scher, R, and Lima, NKC. The effect of different volumes of acute resistance exercise on elderly individuals with treated hypertension. J Strength Cond Res 25(4): 1016-1023, 2011-Acute resistance exercise can reduce the blood pressure (BP) of hypertensive subjects. The aim of this study was to evaluate the effect of different volumes of acute low-intensity resistance exercise over the magnitude and the extent of BP changes in treated hypertensive elderly individuals. Sixteen participants (7 men, 9 women), with mean age of 68 6 5 years, performed 3 independent randomized sessions: Control (C: 40 minutes of rest), Exercise 1 (E1: 20 minutes, 1 lap in the circuit), and Exercise 2 (E2: 40 minutes, 2 laps in the circuit) with the intensity of 40% of 1 repetition maximum. Blood pressure was measured before (during 20 minutes) and after each session (every 5 minutes during 60 minutes) using both a mercury sphygmomanometer and a semiautomatic device (Omrom-HEM-431). After that, 24-hour ambulatory blood pressure monitoring was performed (Dyna-MAPA). Blood pressure decreased during the first 60 minutes (systolic: p < 0.01, diastolic: p < 0.05) after all exercise sessions. Only the highest volume session promoted a reduction of mean systolic 24-hour BP and awake BP (p, 0.05) after exercise, with higher diastolic BP during sleep (p, 0.05). Diastolic 24-hour BP and both systolic and diastolic BP during sleep were higher after E1 (p, 0.05). Concluding, acute resistive exercise sessions in a circuit with different volumes reduced BP during the first 60 minutes after exercise in elderly individuals with treated hypertension. However, only the highest volume promoted a reduction of mean 24-hour and awake systolic BP.National Council for Scientific and Technological Development (CNPq)Foundation for the Support to Education, Research, and Assistance of the University Hospital, Ribeirao Preto School of Medicine (FAEPA

Body composition, muscle strength and quality of active elderly women according to the distance covered in the 6-minute walk test

BACKGROUND: Changes arising from the aging process, particularly changes in body composition, contribute to the functional decline of the elderly.OBJECTIVE: To compare the body composition and muscle strength, mobility and quality in active elderly women according to the distance walked during the 6-minute walk test (6MWT).METHOD: The study included 77 active elderly women aged 65 to 80 years, who were divided into tertiles (A, B and C) according to the distance covered in the 6MWT. We performed anthropometric and clinical evaluations. Body composition was determined by dual energy X-ray absorptiometry (DXA). Handgrip strength (HGS) was measured with a portable dynamometer (Saehan), and knee extension strength (KES) was measured with the one repetition maximum test (1-RM). Functional mobility was assessed by the Timed Up and Go (TUG) test, and body balance was assessed by the Berg Balance Scale (BBS). Muscle quality was defined by the ratio between muscle strength (kgf) and muscle mass (kg).RESULTS: The group that walked the shortest distance in the 6MWT had a higher BMI (A=30.8±7.0, B=27.2±4.2 and C=25.9±3.5 kg/m2), greater amount of fat mass (A=31.3±10.7, B=25.9±6.7 and C=23.81±6.46 kg) lower HGS (A=21.8±5.1, B=22.1±3.5 and C=25.5±5.1 kgf), lower knee extension strength (A=30.6±10.9, B=40.4±12.5 and C=47.2±10.1 kgf), lower arm muscle quality (A=10.1±3.7, B=11.6±2 and C=12.7±2.2 kg) and lower leg muscle quality (A=1.78±1, B=2.84±0.98 and C=3.31±0.77 kg). There was no significant difference between muscle mass (p=0.25) and lean mass (p=0.26).CONCLUSION: Body fat has a negative influence on functional performance, even among active elderly women