City of Lighthouse Point Proclamation

NSU 50th Anniversaryhttps://nsuworks.nova.edu/nsudigital_proclamations/1010/thumbnail.jp

Listen in the Library: The Lighthouse Quartet

The monthly concert series, Listen in the Library, featured student performers in library spaces on the Logan campus. These short, pop-up concerts were one of the ways the USU Libraries was involved in USU’s “Year of the Arts” in 2017-2018. While the library regularly features students’ visual art and exhibits, Listen in the Library brought the performing arts into the space, making student accomplishments in music audible and visible to a community outside the concert hall.https://digitalcommons.usu.edu/music_programs/1159/thumbnail.jp

Instructions for cost keeping

1. The object of this system of cost keeping is to furnish correct information as to the actual cost of every important feature of the work of the Lighthouse Service, This information is of value in preparing estimates, in planning work, in effecting economies, and in comparing the efficiency of different districts, vessels, apparatus, methods, etc. The proposed system is made as simple as practicable, in order to avoid expense and to avoid obscuring the important facts. Separate costs will be kept only of the more important features and classes of expenditures; certain general operating costs, such as tender service and administration, will not be distributed, and liabilities will not be charged in the costs except as hereinafter stated. Expenditures of materials, supplies, and labor will be charged the same as expenditures of money

Where the iris ends and the pupil begins

Specially trained police officers known as Drug Recognition Experts (DRE) use pupil size to determine the type of substance a suspect drug user has taken. The DRE\u27s use a defined program for evaluating pupil sizes. Part of the program consists of taking pupil measurements in standard room illumination as well as in dark room conditions. Three different methods of pupil measurement are taken in the dark room. These measurements are taken with a direct, diffuse, and shielded penlight. The dark room measurements can be difficult to obtain, especially in people with dark iridis. An ultraviolet light source may aid in the measurement of dark irides by causing the lens to fluoresce, thereby silhouetting the pupil. To determine if the UV light source would affect the pupil size differently than the penlight, the two methods were compared. These comparisons were made with the same DRE officer measuring the same subject during two separate sessions. There was no significant difference in pupil sizes between the UV light source and the DRE standard program of pupil measuring. The data collected was also used to determine if the DRE officers are reliable and consistent when evaluating pupils. The DRE officers were accurate to within 0.5mm between the two pupil measurements taken on the same individual at different times. The DRE program has pre-determined pupil size limits for passing and failing suspects. It was found that the upper limit of what the DRE protocol accepts as normal pupil size be raised from 6.5mm to 8.5mm

Development of a Conditional Mesd (Mesoderm Development) Allele for Functional Analysis of the Low-Density Lipoprotein Receptor-Related Family in Defined Tissues

The Low-density lipoprotein receptor-Related Protein (LRP) family members are essential for diverse processes ranging from the regulation of gastrulation to the modulation of lipid homeostasis. Receptors in this family bind and internalize a diverse array of ligands in the extracellular matrix (ECM). As a consequence, LRPs regulate a wide variety of cellular functions including, but not limited to lipid metabolism, membrane composition, cell motility, and cell signaling. Not surprisingly, mutations in single human LRPs are associated with defects in cholesterol metabolism and development of atherosclerosis, abnormalities in bone density, or aberrant eye vasculature, and may be a contributing factor in development of Alzheimer’s disease. Often, members of this diverse family of receptors perform overlapping roles in the same tissues, complicating the analysis of their function through conventional targeted mutagenesis. Here, we describe development of a mouse Mesd (Mesoderm Development) conditional knockout allele, and demonstrate that ubiquitous deletion of Mesdusing Cre-recombinase blocks gastrulation, as observed in the traditional knockout and albino-deletion phenotypes. This conditional allele will serve as an excellent tool for future characterization of the cumulative contribution of LRP members in defined tissues

Utah State Department of Music Jazz Combos

Utah State University Department of Music presents Jazz Combos.https://digitalcommons.usu.edu/music_programs/1136/thumbnail.jp

Radial Construction of an Arterial Wall

SummarySome of the most serious diseases involve altered size and structure of the arterial wall. Elucidating how arterial walls are built could aid understanding of these diseases, but little is known about how concentric layers of muscle cells and the outer adventitial layer are assembled and patterned around endothelial tubes. Using histochemical, clonal, and genetic analysis in mice, here we show that the pulmonary artery wall is constructed radially, from the inside out, by two separate but coordinated processes. One is sequential induction of successive cell layers from surrounding mesenchyme. The other is controlled invasion of outer layers by inner layer cells through developmentally regulated cell reorientation and radial migration. We propose that a radial signal gradient controls these processes and provide evidence that PDGF-B and at least one other signal contribute. Modulation of such radial signaling pathways may underlie vessel-specific differences and pathological changes in arterial wall size and structure.Video Abstrac

Cortical microtubule nucleation can organise the cytoskeleton of Drosophila oocytes to define the anteroposterior axis.

Many cells contain non-centrosomal arrays of microtubules (MTs), but the assembly, organisation and function of these arrays are poorly understood. We present the first theoretical model for the non-centrosomal MT cytoskeleton in Drosophila oocytes, in which bicoid and oskar mRNAs become localised to establish the anterior-posterior body axis. Constrained by experimental measurements, the model shows that a simple gradient of cortical MT nucleation is sufficient to reproduce the observed MT distribution, cytoplasmic flow patterns and localisation of oskar and naive bicoid mRNAs. Our simulations exclude a major role for cytoplasmic flows in localisation and reveal an organisation of the MT cytoskeleton that is more ordered than previously thought. Furthermore, modulating cortical MT nucleation induces a bifurcation in cytoskeletal organisation that accounts for the phenotypes of polarity mutants. Thus, our three-dimensional model explains many features of the MT network and highlights the importance of differential cortical MT nucleation for axis formation.This work was supported in part by the Boehringer Ingelheim Fonds and EPSRC (P. K. T.), core support from the Wellcome Trust [092096] and Cancer Research UK [A14492] (H. D.), the MIT Solomon Buchsbaum Award (J. D.), a Wellcome Trust Principal Research Fellowship [080007] (D. StJ.), the Leverhulme Trust, and the European Research Council Advanced Investigator Grant [247333] (R. E. G.).This is the final version of the article. It first appeared from eLife via http://dx.doi.org/10.7554/eLife.0608

1024 Elementary Particles

<p>This short technical paper presents a new standard model for Elementary Particles. All elementary particle masses are related by simple math. This math is similar to the math used for wifi signals and it is called 1024-QAM. The 1024-QAM table graphically displays how all elementary particles are related, similar to the Standard Periodic Table in chemistry. If we line up all of the particle masses in order, we find there are a number of "gaps." These are called the mass gaps, and they line up perfectly with 1024-QAM, which fits the sequence.</p><p>Supersymmetry (SUSY) is also found to occur with 1024-QAM. Mass Groups 1 thru 8 have heavyweight counterparts which are found in Mass Groups 9 thru 16.  4 new particles are predicted to be discovered between 0.7 to 15 TeV. Also, 4 new particles are predicted to be discovered between 30 to 200 TeV. Numerous other new particles are predicted using 1024-QAM. The only possible explanation for elementary particles to match a QAM pattern, is due to a blinking or discrete universe. This ebook provides compelling evidence that our universe is literally blinking, off and on. This blinking frequency is about 1.1 THz.</p><p>This author challenges scientists in the particle physics field to provide a better model than 1024-QAM, that will fit the "mass gaps." I suggest starting with a QAM model and see what format you think will best fit the experimental data that is already available. In my opinion, the data to support 1024-QAM is already available at CERN, Berkeley, Fermi Lab, Brookhaven, Perimeter Institute, and Stanford. No expensive, new experiment will need to be run.</p&gt