2,273 research outputs found
Controlling single-photon transport with three-level quantum dots in photonic crystals
published_or_final_versio
Reliability of 95% confidence interval revealed by expected quality-of-life scores: an example of nasopharyngeal carcinoma patients after radiotherapy using EORTC QLQ-C 30
<p>Abstract</p> <p>Background</p> <p>Many researchers use observed questionnaire scores to evaluate score reliability and to make conclusions and inferences regarding quality-of-life outcomes. The amount of false alarms from medical diagnoses that would be avoided if observed scores were substituted with expected scores is interesting, and understanding these differences is important for the care of cancer patients. Using expected scores to estimate the reliability of 95% confidence intervals (CIs) is rarely reported in published papers. We investigated the reliability of patient responses to a quality-of-life questionnaire and made recommendations for future studies of the quality of life of patients.</p> <p>Methods</p> <p>A total of 115 patients completed the EORTC core questionnaire QLQ-C30 (version 3) after radiotherapy. The observed response scores, assumed to be one-dimensional, were summed and transformed into expected scores using the Rasch rating scale model with WINSTEPS software. A series of simulations was performed using a unified bootstrap procedure after manipulating scenarios with different questionnaire lengths and patient numbers to estimate the reliability at 95% confidence intervals. Skewness analyses of the 95% CIs were compared to detect different effects between groups according to the two data sets of observed and expected response scores.</p> <p>Results</p> <p>We found that (1) it is necessary to report CIs for reliability and skewness coefficients in papers; (2) data derived from expected response scores are preferable to making inferences; and (3) visual representations displaying the 95% CIs of skewness values applied to item-by-item analyses can provide a useful interpretation of quality-of-life outcomes.</p> <p>Conclusion</p> <p>Reliability coefficients can be reported with 95% CIs by statistical software to evaluate the internal consistency of respondent scores on questionnaire items. The SPSS syntax procedures for estimating the reliability of the 95% CI, expected score generation and visual skewness analyses are demonstrated in this study. We recommend that effect sizes such as a 95% CI be reported along with <it>p </it>values reporting significant differences in quality-of-life studies.</p
Potential misinterpretations caused by collapsing upper categories of comorbidity indices: An illustration from a cohort of older breast cancer survivors
BACKGROUND: Comorbidity indices summarize complex medical histories into concise ordinal scales, facilitating stratification and regression in epidemiologic analyses. Low subject prevalence in the highest strata of a comorbidity index often prompts combination of upper categories into a single stratum (\u27collapsing\u27).
OBJECTIVE: We use data from a breast cancer cohort to illustrate potential inferential errors resulting from collapsing a comorbidity index.
METHODS: Starting from a full index (0, 1, 2, 3, and \u3e/=4 comorbidities), we sequentially collapsed upper categories to yield three collapsed categorizations. The full and collapsed categorizations were applied to analyses of (1) the association between comorbidity and all-cause mortality, wherein comorbidity was the exposure; (2) the association between older age and all-cause mortality, wherein comorbidity was a candidate confounder or effect modifier.
RESULTS: Collapsing the index attenuated the association between comorbidity and mortality (risk ratio, full versus dichotomized categorization: 4.6 vs 2.1), reduced the apparent magnitude of confounding by comorbidity of the age/mortality association (relative risk due to confounding, full versus dichotomized categorization: 1.14 vs 1.09), and obscured modification of the association between age and mortality on both the absolute and relative scales.
CONCLUSIONS: Collapsing categories of a comorbidity index can alter inferences concerning comorbidity as an exposure, confounder and effect modifier
Detection and Recognition of Badgers Using Deep Learning
This paper describes the use of two different deep-learning algorithms for object detection to recognize different badgers. We use recordings of four different badgers under varying background illuminations. In total four different object detection algorithms based on deep neural networks are compared: The single shot multi-box detector (SSD) with the Inception-V2 or MobileNet as a backbone, and the faster region-based convolutional neural network (Faster R-CNN) combined with Inception-V2 or residual networks. Furthermore, two different activation functions are compared to compute probabilities that some badger is in the detected region: the softmax and sigmoid functions. The results of all eight models show that SSD obtains higher recognition accuracies (97.8%–98.6%) than Faster R-CNN (84.8%–91.7%). However, the training time of Faster R-CNN is much shorter than that of SSD. The use of different output activation functions seems not to matter much
Dualities for Loop Amplitudes of N=6 Chern-Simons Matter Theory
In this paper we study the one- and two-loop corrections to the four-point
amplitude of N=6 Chern-Simons matter theory. Using generalized unitarity
methods we express the one- and two-loop amplitudes in terms of dual-conformal
integrals. Explicit integration by using dimensional reduction gives vanishing
one-loop result as expected, while the two-loop result is non-vanishing and
matches with the Wilson loop computation. Furthermore, the two-loop correction
takes the same form as the one-loop correction to the four-point amplitude of
N=4 super Yang-Mills. We discuss possible higher loop extensions of this
correspondence between the two theories. As a side result, we extend the method
of dimensional reduction for three dimensions to five dimensions where dual
conformal symmetry is most manifest, demonstrating significant simplification
to the computation of integrals.Comment: 32 pages and 6 figures. v2: minus sign corrections, ref updated v3:
Published versio
Generation of Three-Qubit Entangled States using Superconducting Phase Qubits
Entanglement is one of the key resources required for quantum computation, so
experimentally creating and measuring entangled states is of crucial importance
in the various physical implementations of a quantum computer. In
superconducting qubits, two-qubit entangled states have been demonstrated and
used to show violations of Bell's Inequality and to implement simple quantum
algorithms. Unlike the two-qubit case, however, where all maximally-entangled
two-qubit states are equivalent up to local changes of basis, three qubits can
be entangled in two fundamentally different ways, typified by the states
and . Here we demonstrate the operation of three coupled
superconducting phase qubits and use them to create and measure
and states. The states are fully characterized
using quantum state tomography and are shown to satisfy entanglement witnesses,
confirming that they are indeed examples of three-qubit entanglement and are
not separable into mixtures of two-qubit entanglement.Comment: 9 pages, 5 figures. Version 2: added supplementary information and
fixed image distortion in Figure 2
The Spectrum of Strings on Warped AdS_3 x S^3
String theory on NS-NS AdS_3 x S^3 admits an exactly marginal deformation
which breaks the SL(2,R)_R x SL(2,R)_L isometry of AdS_3 down to SL(2,R)_R x
U(1)_L. The holographic dual is an exotic and only partially understood type of
two-dimensional CFT with a reduced unbroken global conformal symmetry group. In
this paper we study the deformed theory on the string worldsheet. It is found
to be related by a spectral flow which is nonlocal in spacetime to the
undeformed worldsheet theory. An exact formula for the spectrum of massive
strings is presented.Comment: 26 pages, no figure
Tripartite interactions between two phase qubits and a resonant cavity
The creation and manipulation of multipartite entangled states is important
for advancements in quantum computation and communication, and for testing our
fundamental understanding of quantum mechanics and precision measurements.
Multipartite entanglement has been achieved by use of various forms of quantum
bits (qubits), such as trapped ions, photons, and atoms passing through
microwave cavities. Quantum systems based on superconducting circuits have been
used to control pair-wise interactions of qubits, either directly, through a
quantum bus, or via controllable coupling. Here, we describe the first
demonstration of coherent interactions of three directly coupled
superconducting quantum systems, two phase qubits and a resonant cavity. We
introduce a simple Bloch-sphere-like representation to help one visualize the
unitary evolution of this tripartite system as it shares a single microwave
photon. With careful control and timing of the initial conditions, this leads
to a protocol for creating a rich variety of entangled states. Experimentally,
we provide evidence for the deterministic evolution from a simple product
state, through a tripartite W-state, into a bipartite Bell-state. These
experiments are another step towards deterministically generating multipartite
entanglement in superconducting systems with more than two qubits
Detection of multipartite entanglement with two-body correlations
We show how to detect entanglement with criteria built from simple two-body
correlation terms. Since many natural Hamiltonians are sums of such correlation
terms, our ideas can be used to detect entanglement by energy measurement. Our
criteria can straightforwardly be applied for detecting different forms of
multipartite entanglement in familiar spin models in thermal equilibrium.Comment: 5 pages including 2 figures, LaTeX; for the proceedings of the DPG
spring meeting, Berlin, March 200
Stage-Dependent Tolerance of the German Cockroach, Blattella germanica for Dichlorvos and Propoxur
Stage-dependent dichlorvos and propoxur tolerance in a field population of the German cockroach, Blattella germanica Linnaeus (Blatodea: Blattellidae), was investigated in the laboratory using a topical application bioassay. The results showed the 6 week-old nymphs were more tolerant to dichlorvos and propoxur than the other ages tested. LD50 values of dichlorvos and propoxur for the 6 week-old nymphs were 2.003 µµg per insect and 5.296 µµg per insect, respectively. Tolerance ratios of 18.55-fold and 4.98-fold for LD50 were obtained from 6-week-old nymphs compared to 4 week-old nymphs. The specific activity of acetylcholinesterase (AChE) from 1 week-old nymphs was the highest among all tested developmental stages of nymphs and adult males and females. The specific activity of AChE decreased significantly with increasing age. The sensitivity of AChE to dichlorvos was the highest with a ki value of 3.12××104 mol-1min-1 in the last nymphal stage of B. germanica (about 6 weeks-old). The AChE from 4 week-old nymphs was the most sensitive to propoxur, with the highest ki value being 2.63××105 mol-1min-1. These results indicated that the different developmental stages and sexes of B. germanica affected the inhibition of AChE by dichlorvos and propoxur
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