Adjustment to colostomy: stoma acceptance, stoma care self-efficacy and interpersonal relationships

‘The definitive version is available at www.blackwell-synergy.com.’ Copyright Blackwell Publishing. DOI: 10.1111/j.1365-2648.2007.04446.xThis paper is a report of a study to examine adjustment and its relationship with stoma acceptance and social interaction, and the link between stoma care self-efficacy and adjustment in the presence of acceptance and social interactions.Peer reviewe

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

How will the ebola crisis impact the HIV epidemic?

10.1186/s12977-014-0110-zRetrovirology11111

Experimental Pathways towards Developing a Rotavirus Reverse Genetics System: Synthetic Full Length Rotavirus ssRNAs Are Neither Infectious nor Translated in Permissive Cells

10.1371/journal.pone.0074328PLoS ONE89e7432

Atypical working memory decline across the adult lifespan in autism spectrum disorder?

Whereas working memory (WM) performance in typical development increases across childhood and adolescence, and decreases during adulthood, WM development seems to be delayed in young individuals with autism spectrum disorder (ASD). How WM changes when individuals with ASD grow old is largely unknown. We bridge this gap with a cross-sectional study comparing age-related patterns in WM performance (n-back task: 3 load levels) among a large sample of individuals with and without ASD (N = 275) over the entire adult life span (19-79 years) as well as interindividual differences therein. Results demonstrated that, despite longer RTs, adults with ASD showed similar WM performance to adults without ASD. Age-related differences appeared to be different among adults with and without ASD as adults without ASD showed an age-related decline in WM performance, which was not so evident in adults with ASD. Moreover, only IQ scores reliably dissociated interindividual differences in age-gradients, but no evidence was found for a role of basic demographics, comorbidities, and executive functions. These findings provide initial insights into how ASD modulates cognitive aging, but also underline the need for further WM research into late adulthood in ASD and for analyzing individual change trajectories in longitudinal studies

The contrasting relationships between betaine and homocysteine in two clinical cohorts are associated with plasma lipids and drug treatments

10.1371/journal.pone.0032460PLoS ONE73e3246