969 research outputs found

    A Robust Filter for the BeppoSAX Gamma Ray Burst Monitor Triggers

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    The BeppoSAX Gamma Ray Burst Monitor (GRBM) is triggered any time a statistically significant counting excess is simultaneously revealed by at least two of its four independent detectors. Several spurious effects, including highly ionizing particles crossing two detectors, are recorded as onboard triggers. In fact, a large number of false triggers is detected, in the order of 10/day. A software code, based on an heuristic algorithm, was written to discriminate between real and false triggers. We present the results of the analysis on an homogeneous sample of GRBM triggers, thus providing an estimate of the efficiency of the GRB detection system consisting of the GRBM and the software.Comment: Proc. 5th Huntsville GRB Symposiu

    Cmv-specific cell-mediated immunity in immunocompetent adults with primary cmv infection: A case series and review of the literature

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    Cytomegalovirus-specific cell-mediated immunity (CMV-CMI) in actively infected healthy immunocompetent hosts has been poorly investigated. Conversely, correlates of maternal protective immunity for the fetus after primary infection in pregnancy continue to be studied. The kinetics and magnitude of CMV-specific CMI in immunocompetent primary CMV-infected adults are described. A literature review on CMV-CMI in primarily infected pregnant women and its correlation to the risk of vertical virus transmission is included. Immunological measurements after infection were performed by enzyme-linked ImmunoSPOT assay enumerating IFN-Îł secreting CMV-specific T cells, at a single cell level, upon in vitro stimulation with viral antigens. Simultaneously, serological and virological profiles of infected patients were investigated. Patients displayed mild-to-moderate clinical and laboratory profiles for infection, and all showed positive EliSpot results in the early stage of infection (<20 days after onset). The virus-CMI was strong in the majority of patients (58.8%) in which the lowest CMV-DNAemia levels (<300 copies/mL) were detected. Significantly higher viral loads were observed in patients with weak CMV-CMI at the same time-point post-infection (up to 15,104 copies/mL; p < 0.001). T cell response magnitudes to IE-1 and pp65-UL83 peptides were overlapping and stable over time. In these case series, the early presence of CMV-CMI was probably pivotal in controlling viral replication and led to spontaneous viral clearance

    Thermal and rheological behavior of native and modified starch Araucaria angustifolia (pinhĂŁo).

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    Araucaria angustifolia is known in Brazil as Paraná Pine is endangered due to reckless extraction. The preservation and maintenance of the culture could be stimulated by use derivative products like the starch from its seeds (pinhĂŁo). In this work were studied samples of unmodified and modified pinhĂŁo starch. The hydrogen peroxide (H2O2) were used in the concentrations 0.1, 0.2 and 0.3 mol.L-1 (a, b, c) and simultaneously exposed in ultraviolet rays (λ = 256 nm) for one hour. One sample (N) was maintained as received for comparisons of the analysis results. The samples were analyzed by the thermoanalytical techniques: thermogravimetry and differential thermal analysis (TG-DTA) and differential scanning calorimetry (DSC); and by the rheological analysis: Rapid Viscoamylographic Analysis (RVA). The TGA showed an increase on the stability values form the (N) sample to the modified ones. The DSC showed a strong decrease on the gelatinization enthalpy with increasing of the H2O2 concentrations solutions valued for the modified samples. The RVA results presented that the Setback reduced with the treatment that used hydrogen peroxide in a higher concentration. The obtained results showed that the modification method applied altered the thermal behavior of the pinhĂŁo starch.CBRATEC

    A case report of chondrocalcinosis of the temporomandibular joint: Surgical management and literature review

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    Background: Chondrocalcinosis is a metabolic disorder characterized by non-infectious joint inflammation with intra- or periarticular calcification. Temporomandibular (TMJ) chondrocalcinosis is rare and not usually included in the differential diagnosis of TMJ and facial pain disorders. Case report: A 67-year-old woman presented with a calcified mass in the right TMJ between the condyle and glenoid fossa, eroding into the floor of the middle cranial fossa due to calcium pyrophosphate deposition in the TMJ. She underwent surgical excision of the mass with immediate econstruction with a custom-made prosthesis. On follow-up, there was complete clinical resolution, with no evidence of recurrence. Literature related to surgical treatment of chondrocalcinosis of TMJ and its treatment was reviewed. Surgery is the most commonly used treatment. A custom-made device allowed us to bridge the defect caused by the destructive disease process. Conclusion: Custom-made prostheses can be considered a safe and effective solution in erosive forms of chondrocalcinosis, replacing the TMJ to restore functionality and correct the anatomical defect

    Registros e análises de informações para o gerenciamento eficiente de empresas rurais.

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    A importância das informações para o processo decisório; Ferramentas gerenciais desenvolvidas pela pesquisa; Considerações finais.bitstream/item/59149/1/Documentos-220.pd

    Effect of the KMnO4 treatment on the "pinhĂŁo" starch.

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    O pinhão, sementes de Araucaria angustifolia, tem o amido como componente principal. Os amidos oxidados melhoram as características físico-química, de pasta e térmicas dos produtos em processos industriais. O amido de pinhão nativo foi tratado com soluções padronizadas de permanganato de potássio (KMnO4) e as amostras foram analisadas por técnicas termoanalíticas (TG-DTA) em atmosfera inerte. As amostras foram oxidadas da seguinte forma: quatro porções de 20 g (base seca) foram separadas e três foram suspensas em solução de KMnO4 (0,001; 0,002; 0,005 mol L-1) em agitação constante durante 30 minutos, a quarta amostra foi mantida como recebida. As suspensões de amido foram filtradas, lavadas, secas e analisadas. As modificações oxidativas provocaram mudanças estruturais das moléculas de amido, registradas pelos diferentes resultados calculados a partir das curvas TGA e DTA. A amostra (3) teve as mudanças mais significativas na degradação com o 3ª evento exotérmico com temperaturas acima de 330 °C

    Effect of treatment with hcl/alcoholic in the modification of corn starch.

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    Corn is the cereal most produced in the world. Corn starches were modified by HCl 0.1 mol L-1 in alcoholic and aqueous solutions. Three mass losses can be observed in the degradation process using TG-DTG curve. The native and treated starches samples don't show differences in the stability region. With DSC curves were observed lower values of the ΔH of gelatinization of the modified starch by HCl in the alcoholic solutions. The modifications using alcoholic solutions demonstrated a good alternative to obtain modifies starches.Edição dos Anais do 7Âş SimpĂłsio de Análise TĂ©rmica, 2015, Bauru

    UV-Induced Structural Changes of Model DNA Helices Probed by Optical Spectroscopy

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    International audienceChemical alterations of DNA, if not repaired, may lead to carcinogenic mutations. Structural modifications of the helix around the lesion enable its recognition by repair enzymes. We have used absorption spectroscopy and mass spectrometry to detect structural changes provoked by cyclobutane thymine dimers, the major lesion induced by UV radiation. We found that formation of a cyclobutane dimer in the model duplex (dA)20 · (dT)20 destroys base stacking on the adenine strand. The physical background of this novel approach is the existence of charge-transfer states among neighboring bases, whose contribution to the hypochromism of the helix disappears following destacking
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