Analyse du récit de la résurrection de Lazare (Jean 11, 1-12,11) : de la narration au sens

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal

Les inhibiteurs de l'HMG-CoA réductase en prévention de la maladie d'Alzheimer : minimiser l'effet du biais d'indication

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal

L'importance du geste dans l'évaluation de la cinématique tridimensionnelle du genou

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal

Évaluation in vitro de la résistance au glissement des fils orthodontiques esthétiques en acier inoxydable

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal

A longitudinal pilot study on cognition and cerebral hemodynamics in a mouse model of preeclampsia superimposed on hypertension : looking at mothers and their offspring

Preeclampsia is a common hypertensive disorder in pregnant women and whose causes and consequences have focused primarily on cardiovascular outcomes on the mother and offspring, often without taking into consideration the possible effects on the brain. One possible cause of preeclampsia has been attributed to alterations in the renin-angiotensin system, which has also been linked to cognitive decline. In this pilot study, we use a transgenic mouse model that chronically overexpresses human angiotensinogen and renin (R+A + mice) that displayed characteristics of preeclampsia such as proteinuria during gestation. Offspring of these mothers as well as from control mothers were also examined. We were primarily interested in detecting whether cognitive deficits were present in the mothers and offspring in the long term and used a spatial learning and memory task as well as an object recognition task at three timepoints: 3, 8, and 12 months post-partum or post-natal, while measuring blood pressure and performing urine analysis after each timepoint. While we did not find significant deficits in preeclamptic mothers at the later timepoints, we did observe negative consequences in the pups of R+A + mice that coincided with hemodynamic alterations whereby pups had higher whisker-evoked oxygenated hemoglobin levels and increased cerebral blood flow responses compared to control pups. Our study provides validation of this preeclampsia mouse model for future studies to decipher the underlying mechanisms of long-term cognitive deficits found in offspring

Effect of aneurysm size on procedure-related rupture in patients with subarachnoid hemorrhage treated with coil occlusion

Objective: Procedure-related rupture is one of the most feared complications in treating patients with cerebral aneurysm. The primary aim of this study was to estimate the effect of aneurysm size on procedure-related rupture. We also estimated its effect on peri-procedural thromboembolic events. Methods: This observational study was conducted using routinely-collected health data on patients admitted for subarachnoid hemorrhage and treated with aneurysm coil occlusion in the CHU de Québec — Enfant-Jésus hospital from January 1st, 2000 until sample size was reached. Patients were identified from the Discharge Abstract Database using the Canadian Classification of Health codes. Assessment of complications was blind to aneurysm size. Logistic regression models were performed to test associations between aneurysm size and procedure-related rupture or peri-procedural thromboembolic events, and between both procedure-related rupture and thromboembolic events and patients' outcomes. Results: This study included 532 aneurysms treated with coil occlusion in 505 patients. Procedure-related rupture occurred in 34 patients (6.7%) and thromboembolic events in 53 (10.5%) patients. Aneurysms of 2 to 3 mm inclusively were not more significantly associated with procedure-related rupture or thromboembolic events than those larger than 3 mm (OR 1.02, 95% CI: 0.9–1.16, p = 0.78 and OR 1.06, 95% CI: 0.96–1.17, p = 0.3, respectively). However, procedure-related rupture had a significant effect on patient mortality (OR 3.86, 95% CI: 1.42–10.53, p < 0.01). Conclusions: Very small aneurysm size should not preclude aneurysm coil occlusion. Every measure should be taken to prevent procedure-related rupture as it is strongly associated with higher mortality

Enjeux et solutions pour la sylviculture intensive de plantations dans un contexte d'aménagement écosystémique

Les plantations forestières représentent un outil sylvicole reconnu pour assurer un approvisionnement en matière ligneuse qui répond aux attentes de la société envers l'aménagement durable des forêts. Toutefois, elles font aussi partie du scénario sylvicole qui a le plus grand potentiel d'artificialisation de la forêt naturelle. Les objectifs de la sylviculture intensive de plantations peuvent alors paraître, de prime abord, en contradiction avec ceux de l'aménagement écosystémique. Nous décrivons le processus par lequel nous avons défini et documenté des enjeux associés aux plantations et proposé des pistes de solutions pour que la sylviculture intensive de plantations puisse s'intégrer à l'aménagement écosystémique. Nous avons identifié des enjeux relatifs à l'ampleur, à la localisation et à l'agencement spatial des plantations, aux attributs clés et à la résilience de la forêt naturelle, à l'acceptabilité sociale, ainsi qu’à la productivité et à la rentabilité des plantations. Nous avons également proposé des pistes de solutions qui permettraient de réaliser les plantations dans un contexte d'aménagement écosystémique, telles que la modulation des traitements sylvicoles pour augmenter la naturalité des plantations, la réalisation des traitements de manière à obtenir la production attendue, ainsi qu'un déploiement dans le paysage qui intègre les préoccupations des parties prenantes et qui considère la naturalité de la matrice forestière. Forest plantations are recognized as a silvicultural tool for ensuring a timber supply that meets public expectations regarding sustainable forest management. However, they are also part of the silvicultural scenario that shows the greatest potential for the artificialization of natural forests. From a firsthand perspective, intensive plantation silviculture objectives may appear antagonistic to those of ecosystem management. Here we describe the process through which we defined and documented plantation issues, then propose potential solutions to allow the integration of intensive plantation silviculture into ecosystem management. We identify issues related to the scale, localization and spatial arrangement of plantations, the key attributes and resilience of natural forests, social acceptability, and the productivity and profitability of plantations. We also propose potential solutions likely to help manage plantations within a context of ecosystem management. These include modulating silvicultural treatments to enhance the naturalness of plantations, conducting treatments to obtain expected production rates, and ensuring that plantations are deployed across the landscape in a manner that integrates stakeholder concerns and considers the naturalness of the forest matrix

Krach, bonnes nouvelles et réactions à Bruxelles, Toronto et New York

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