PHYTOCHEMISTRY AND PHARMACOLOGICAL BIO-ACTIVITIES OF LANNEA COROMANDELICA: A REVIEW

Lannea coromandelica is extensively employed as a medicinal herb across the globe. This research work focuses primarily on the phytochemistry, pharmaceutics, and bio-exertion of L. coromandelica. In ethnomedicine, several members of this species function as astringents, aiding in anti-oxidant, anti-inflammatory, and anti-diabetic and are helpful in other physiological functions. In addition, Lannea species’ therapeutic benefits were acknowledged in numerous scientific investigations. The conclusions derived from the current study corroborate that the therapeutic activities of L. coromandelica can be linked to the presence of a broad spectrum of secondary metabolites and bioactive phytocompounds such as phenols, flavonoids, tannins, and proteins, according to the current study. This review highlights phyto-assembly and phyto-activities such as a diuretic, cardiovascular, and bioactivities such as antiepileptic, antimicrobial, and anti-convulsant, and pharmaceutical activities such as anti-cancer, anti-diabetic, and anti-asthmatic properties

A case of reversible upper brachial plexopathy following CRT-P implantation

Brachial plexus injury is a challenging field of hand and upper extremity surgery. Presently available microsurgical techniques and functional gains are rewarding in upper plexus injuries. Cardiac electronic devices implantation rate is the required to manage long-term complications. Cardiac resynchronization therapy (CRT) implantation is a commoner procedure done for severe ischaemic and non ischaemic cardiomyopathy. A 65-year-old male patient underwent CRT device implantation via utilizing his left subclavian vein with a classical incision over the delto pectoral groove, with right ventricular lead on the inter ventricular septum and left ventricular lead into the posterolateral branch of coronary sinus with RA threshold, impedance and amplitude (P) of 1V and 690ohm and 7.8mv respectively. CRT with adjacent nerve structure is carefully selected for vein puncture to minimize the risk of Brachial plexus injury, i.e. pacing lead induces nerve injury. Peripheral nerve injuries are sparsely reported due to procedural as well as indwelling trans venous pacing leads and isolated posterior cord involvement is a rarer presentation hence is reported

Comparison of vitamin D levels in obese and non obese patients with polycystic ovarian syndrome in a South Indian population

Polycystic ovary syndrome (PCOS) is the most common metabolic abnormality occurring in young women of reproductive age. Low vitamin D levels were found to be associated with the development of obesity and insulin resistance in young women with PCOS. The study was conducted as a prospective observational study involving 121 women with PCOS. The diagnosis of PCOS cases were based on the revised Rotterdam consensus criteria. Vitamin D levels were compared in the obese and non obese PCOS groups and also with the controls. In the PCOS group, sixty subjects were obese with BMI of ≥25 kg/m2 and forty seven subjects were found to be non obese. In the control group, sixteen subjects were obese and sixty five subjects were non obese. The mean vitamin D level in the PCOS group was 15.45±7.88 ng/ml and in the control group was 12.83±5.76ng/ml. The mean vitamin D levels in the obese and non obese group with PCOS were 16.11±8.9ng/ml and 14.61±6.1ng/ml respectively. Majority of the patients and controls had vitamin D deficiency and there was no difference in the vitamin D levels in PCOS group and controls as well as obese and non obese groups

Effect of Noise in Optically-Fed Phased Array Antennas for CDMA Wireless Networks

The characteristics of an optically fed phased array antenna are affected by the amplitude and phase noise introduced by optical amplifiers (EDFA) used in the system. A theoretical derivation and a numerical computation of the effect of phase noise on antenna performance are given in this paper. The phase fluctuations make the main beam to jitter around a mean value directly related to the mean and the variance of the amplified spontaneous emission induced random phase change

Architecture and Applications of IoT Devices in Socially Relevant Fields

Number of IoT enabled devices are being tried and introduced every year and there is a healthy competition among researched and businesses to capitalize the space created by IoT, as these devices have a great market potential. Depending on the type of task involved and sensitive nature of data that the device handles, various IoT architectures, communication protocols and components are chosen and their performance is evaluated. This paper reviews such IoT enabled devices based on their architecture, communication protocols and functions in few key socially relevant fields like health care, farming, firefighting, women/individual safety/call for help/harm alert, home surveillance and mapping as these fields involve majority of the general public. It can be seen, to one's amazement, that already significant number of devices are being reported on these fields and their performance is promising. This paper also outlines the challenges involved in each of these fields that require solutions to make these devices reliableComment: 1

Is GIS Appropriate Technology

Abstract. Appropriate technology(AT) has become an integral part if the programmes for decentralized regional development in the third world appropriate techniques are usually low in capital costs-they can be maintained without a high level of expertise, and they do not involve patents, expensive copyrights and royalties. By these criteria a commercial geographical information system(GIS) is not an appropriate technology to be used in decentralized development. However, the use of local renewable resources involves the adoption of end-use analysis for matching end -uses to specific sources so as to minimize the consumption of material and energy ( i.e. minimize entropy ). This matching requires an inverse increase in information which leads to what may be called the information-entropy trade-?; minimization of entropy requires an inverse increase in information. In this respect computers and GIS have an important contribution to make to decentralized regional planning. Drawing on a case study in Sri Lanka, this paper presents some ideas on how to incorporate GIS into local-level planning information systems

In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules

Candida infections have created a great burden on the public healthcare sector. The situation is worsened by recent epidemiological changes. Furthermore, the current arsenal of antifungal agents is limited and associated with undesirable drawbacks. Therefore, new antifungal agents that surpass the existing ones are urgently needed. High-throughput screening of small molecule libraries enables rapid hit identification and, possibly, increases hit rate. Moreover, the identified hits could be associated with unrecognized or multiple drug targets, which would provide novel insights into the biological processes of the pathogen. Hence, it is proposed that high-throughput screening of small molecules is particularly important in the pursuit of the ideal antifungal agents for Candida infections