58 research outputs found
Zimbabwe National Cancer Registry: summary data, 1986-1989
A summary data of the national registry of cancer in Zimbabwe in the period 1986 to 1989.The Zimbabwe National Cancer Registry began operation in 1986. Between 1986-1989, a total of 8 276 cases were identified. Among men of African descent, oesophageal (11,2 pc) and liver cancer (11,0 pc) were most common. Cervical cancer was by far the most common among women of African descent (34,5 pc). Among both males and females of non-African descent, skin cancers (other than melanoma) accounted for one-third of cancers followed by prostate cancer (7,7 pc) in males and breast cancer (18,5 pc) in females. These findings arc comparable to earlier reports of the epidemiology of cancer in Zimbabwe
Reheating and turbulence
We show that the ''turbulent'' particle spectra found in numerical
simulations of the behavior of matter fields during reheating admit a simple
interpretation in terms of hydrodynamic models of the reheating period. We
predict a particle number spectrum with for Comment: 10 pages, one figure included in tex
Gravitational collapse of a Hagedorn fluid in Vaidya geometry
The gravitational collapse of a high-density null charged matter fluid,
satisfying the Hagedorn equation of state, is considered in the framework of
the Vaidya geometry. The general solution of the gravitational field equations
can be obtained in an exact parametric form. The conditions for the formation
of a naked singularity, as a result of the collapse of the compact object, are
also investigated. For an appropriate choice of the arbitrary integration
functions the null radial outgoing geodesic, originating from the shell
focussing central singularity, admits one or more positive roots. Hence a
collapsing Hagedorn fluid could end either as a black hole, or as a naked
singularity. A possible astrophysical application of the model, to describe the
energy source of gamma-ray bursts, is also considered.Comment: 14 pages, 2 figures, to appear in Phys. Rev.
Cosmological Non-Linearities as an Effective Fluid
The universe is smooth on large scales but very inhomogeneous on small
scales. Why is the spacetime on large scales modeled to a good approximation by
the Friedmann equations? Are we sure that small-scale non-linearities do not
induce a large backreaction? Related to this, what is the effective theory that
describes the universe on large scales? In this paper we make progress in
addressing these questions. We show that the effective theory for the
long-wavelength universe behaves as a viscous fluid coupled to gravity:
integrating out short-wavelength perturbations renormalizes the homogeneous
background and introduces dissipative dynamics into the evolution of
long-wavelength perturbations. The effective fluid has small perturbations and
is characterized by a few parameters like an equation of state, a sound speed
and a viscosity parameter. These parameters can be matched to numerical
simulations or fitted from observations. We find that the backreaction of
small-scale non-linearities is very small, being suppressed by the large
hierarchy between the scale of non-linearities and the horizon scale. The
effective pressure of the fluid is always positive and much too small to
significantly affect the background evolution. Moreover, we prove that
virialized scales decouple completely from the large-scale dynamics, at all
orders in the post-Newtonian expansion. We propose that our effective theory be
used to formulate a well-defined and controlled alternative to conventional
perturbation theory, and we discuss possible observational applications.
Finally, our way of reformulating results in second-order perturbation theory
in terms of a long-wavelength effective fluid provides the opportunity to
understand non-linear effects in a simple and physically intuitive way.Comment: 84 pages, 3 figure
Model-independent dark energy test with sigma_8 using results from the Wilkinson Microwave Anisotropy Probe
By combining the recent WMAP measurements of the cosmic microwave background
anisotropies and the results of the recent luminosity distance measurements to
type-Ia supernovae, we find that the normalization of the matter power spectrum
on cluster scales, sigma_8, can be used to discriminate between dynamical
models of dark energy (quintessence models) and a conventional cosmological
constant model (LCDM).Comment: 5 pages, 6 figures. Additional discussion and reference, matches PRD
accepted versio
Large-scale magnetic fields from inflation due to a -even Chern-Simons-like term with Kalb-Ramond and scalar fields
We investigate the generation of large-scale magnetic fields due to the
breaking of the conformal invariance in the electromagnetic field through the
-even dimension-six Chern-Simons-like effective interaction with a fermion
current by taking account of the dynamical Kalb-Ramond and scalar fields in
inflationary cosmology. It is explicitly demonstrated that the magnetic fields
on 1Mpc scale with the field strength of G at the present time
can be induced.Comment: 18 pages, 6 figures, version accepted for publication in Eur. Phys.
J.
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia
Tandem repeat expansions (TREs) are associated with over 60 monogenic disorders and have recently been implicated in complex disorders such as cancer and autism spectrum disorder. The role of TREs in schizophrenia is now emerging. In this study, we have performed a genome-wide investigation of TREs in schizophrenia. Using genome sequence data from 1154 Swedish schizophrenia cases and 934 ancestry-matched population controls, we have detected genome-wide rare (<0.1% population frequency) TREs that have motifs with a length of 2â20 base pairs. We find that the proportion of individuals carrying rare TREs is significantly higher in the schizophrenia group. There is a significantly higher burden of rare TREs in schizophrenia cases than in controls in genic regions, particularly in postsynaptic genes, in genes overlapping brain expression quantitative trait loci, and in brain-expressed genes that are differentially expressed between schizophrenia cases and controls. We demonstrate that TRE-associated genes are more constrained and primarily impact synaptic and neuronal signaling functions. These results have been replicated in an independent Canadian sample that consisted of 252 schizophrenia cases of European ancestry and 222 ancestry-matched controls. Our results support the involvement of rare TREs in schizophrenia etiology
Extended Theories of Gravity and their Cosmological and Astrophysical Applications
We review Extended Theories of Gravity in metric and Palatini formalism
pointing out their cosmological and astrophysical application. The aim is to
propose an alternative approach to solve the puzzles connected to dark
components.Comment: 44 pages, 11 figure
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