11,918 research outputs found
High strength alloy for immediate temperature, 24 24 to 704 C (75 to 1300 F), applications
Application of prealloyed powder technology to the NASA-TRW-VI-A alloy shows the potential of highly alloyed normally cast superalloys for achieving superior properties at intermediate temperatures
Local and global instabilities of flow in a flexible-walled channel
We consider laminar high-Reynolds-number flow through a long finite-length planar channel, where a segment of one wall is replaced by a massless membrane held under longitudinal tension. The flow is driven by a fixed pressure difference across the channel and is described using an integral form of the unsteady boundary-layer equations. The basic flow state, for which the channel has uniform width, exhibits static and oscillatory global instabilities, having distinct modal forms. In contrast, the corresponding local problem (neglecting boundary conditions associated with the rigid parts of the system) is found to be convectively, but not absolutely, unstable to small-amplitude disturbances in the absence of wall damping. We show how amplification of the primary global oscillatory instability can arise entirely from wave reflections with the rigid parts of the system, involving interacting travelling wave flutter and static-divergence modes that are convectively stable; alteration of the mean flow by oscillations makes the onset of this primary instability subcritical. We also show how distinct mechanisms of energy transfer differentiate the primary global mode from other modes of oscillatory instability
Revised time-of-flight calculations for high-latitude geomagnetic pulsations using a realistic magnetospheric magnetic field model
We present a simple time-of-flight analysis of Alfvén pulsations standing on closed terrestrial magnetic field lines. The technique employed in this study in order to calculate the characteristic period of such oscillations builds upon earlier time-of-flight estimates via the implementation of a more recent magnetospheric magnetic field model. In this case the model employed is the Tsyganenko (1996) field model, which includes realistic magnetospheric currents and the consequences of the partial penetration of the interplanetary magnetic field into the dayside magnetopause. By employing a simple description of magnetospheric plasma density, we are therefore able to estimate the period of standing Alfvén waves on geomagnetic field lines over a significantly wider range of latitudes and magnetic local times than in previous studies. Furthermore, we investigate the influence of changing season and upstream interplanetary conditions upon the period of such pulsations. Finally, the eigenfrequencies of magnetic field lines computed by the time-of-flight technique are compared with corresponding numerical solutions to the wave equation and experimentally observed pulsations on geomagnetic field lines
A two-fluid model for tissue growth within\ud a dynamic flow environment
We study the growth of a tissue construct in a perfusion bioreactor, focussing on its response to the mechanical environment. The bioreactor system is modelled as a two-dimensional channel containing a tissue construct through which a flow of culture medium is driven. We employ a multiphase formulation of the type presented by G. Lemon, J. King, H. Byrne, O. Jensen and K. Shakesheff in their study (Multiphase modelling of tissue growth using the theory of mixtures. J. Math. Biol. 52(2), 2006, 571–594) restricted to two interacting fluid phases, representing a cell population (and attendant extracellular matrix) and a culture medium, and employ the simplifying limit of large interphase viscous drag after S. Franks in her study (Mathematical Modelling of Tumour Growth and Stability. Ph.D. Thesis, University of Nottingham, UK, 2002) and S. Franks and J. King in their study (Interactions between a uniformly proliferating tumour and its surrounding: Uniform material properties. Math. Med. Biol. 20, 2003, 47–89).\ud
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The novel aspects of this study are: (i) the investigation of the effect of an imposed flow on the growth of the tissue construct, and (ii) the inclusion of a mechanotransduction mechanism regulating the response of the cells to the local mechanical environment. Specifically, we consider the response of the cells to their local density and the culture medium pressure. As such, this study forms the first step towards a general multiphase formulation that incorporates the effect of mechanotransduction on the growth and morphology of a tissue construct. The model is analysed using analytic and numerical techniques, the results of which illustrate the potential use of the model to predict the dominant regulatory stimuli in a cell population
Bifurcations and dynamics emergent from lattice and continuum models of bioactive porous media
We study dynamics emergent from a two-dimensional reaction--diffusion process
modelled via a finite lattice dynamical system, as well as an analogous PDE
system, involving spatially nonlocal interactions. These models govern the
evolution of cells in a bioactive porous medium, with evolution of the local
cell density depending on a coupled quasi--static fluid flow problem. We
demonstrate differences emergent from the choice of a discrete lattice or a
continuum for the spatial domain of such a process. We find long--time
oscillations and steady states in cell density in both lattice and continuum
models, but that the continuum model only exhibits solutions with vertical
symmetry, independent of initial data, whereas the finite lattice admits
asymmetric oscillations and steady states arising from symmetry-breaking
bifurcations. We conjecture that it is the structure of the finite lattice
which allows for more complicated asymmetric dynamics. Our analysis suggests
that the origin of both types of oscillations is a nonlocal reaction-diffusion
mechanism mediated by quasi-static fluid flow.Comment: 30 pages, 21 figure
Lattice and Continuum Modelling of a Bioactive Porous Tissue Scaffold
A contemporary procedure to grow artificial tissue is to seed cells onto a
porous biomaterial scaffold and culture it within a perfusion bioreactor to
facilitate the transport of nutrients to growing cells. Typical models of cell
growth for tissue engineering applications make use of spatially homogeneous or
spatially continuous equations to model cell growth, flow of culture medium,
nutrient transport, and their interactions. The network structure of the
physical porous scaffold is often incorporated through parameters in these
models, either phenomenologically or through techniques like mathematical
homogenization. We derive a model on a square grid lattice to demonstrate the
importance of explicitly modelling the network structure of the porous
scaffold, and compare results from this model with those from a modified
continuum model from the literature. We capture two-way coupling between cell
growth and fluid flow by allowing cells to block pores, and by allowing the
shear stress of the fluid to affect cell growth and death. We explore a range
of parameters for both models, and demonstrate quantitative and qualitative
differences between predictions from each of these approaches, including
spatial pattern formation and local oscillations in cell density present only
in the lattice model. These differences suggest that for some parameter
regimes, corresponding to specific cell types and scaffold geometries, the
lattice model gives qualitatively different model predictions than typical
continuum models. Our results inform model selection for bioactive porous
tissue scaffolds, aiding in the development of successful tissue engineering
experiments and eventually clinically successful technologies.Comment: 38 pages, 16 figures. This version includes a much-expanded
introduction, and a new section on nonlinear diffusion in addition to polish
throughou
High-temperature strength of prealloyed-powder products increased by heat/pressure treatment
Heat treatment process involves heating products to a temperature above the solidus, and subsequently applying pressure at a temperature below the solidus. Technique can be modified to one step process involving simultaneous application if both high pressure and heat. Process is not limited to cobalt-base alloys
Laboratory mid-IR spectra of equilibrated and igneous meteorites. Searching for observables of planetesimal debris
Meteorites contain minerals from Solar System asteroids with different
properties (like size, presence of water, core formation). We provide new
mid-IR transmission spectra of powdered meteorites to obtain templates of how
mid-IR spectra of asteroidal debris would look like. This is essential for
interpreting mid-IR spectra of past and future space observatories, like the
James Webb Space Telescope. We show that the transmission spectra of wet and
dry chondrites, carbonaceous and ordinary chondrites and achondrite and
chondrite meteorites are distinctly different in a way one can distinguish in
astronomical mid-IR spectra. The two observables that spectroscopically
separate the different meteorites groups (and thus the different types of
parent bodies) are the pyroxene-olivine feature strength ratio and the peak
shift of the olivine spectral features due to an increase in the iron
concentration of the olivine
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