863 research outputs found

    Atom-dimer scattering and long-lived trimers in fermionic mixtures

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    We consider a heteronuclear fermionic mixture on the molecular side of an interspecies Feshbach resonance and discuss atom-dimer scattering properties in uniform space and in the presence of an external confining potential, restricting the system to a quasi-2D geometry. We find that there is a peculiar atom-dimer p-wave resonance which can be tuned by changing the frequency of the confinement. Our results have implications for the ongoing experiments on Lithium-Potassium mixtures, where this mechanism allows for switching the p-wave interaction between a K atom and Li-K dimer from attractive to repulsive, and forming a weakly bound trimer with unit angular momentum. We show that such trimers are long-lived and the atom-dimer resonance does not enhance inelastic relaxation in the mixture, making it an outstanding candidate for studies of p-wave resonance effects in a many-body system.Comment: 4 pages, 2 figures, published versio

    Evaporation limited loading of an atom trap

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    Recently, we have experimentally demonstrated a continuous loading mechanism for an optical dipole trap from a guided atomic beam [1]. The observed evolution of the number of atoms and temperature in the trap are consequences of the unusual trap geometry. In the present paper, we develop a model based on a set of rate equations to describe the loading dynamics of such a mechanism. We consider the collision statistics in the non-uniform trap potential that leads to twodimensional evaporation. The comparison between the resulting computations and experimental data allows to identify the dominant loss process and suggests ways to enhance the achievable steady-state atom number. Concerning subsequent evaporative cooling, we find that the possibility of controlling axial and radial confinement independently allows faster evaporation ramps compared to single beam optical dipole traps.Comment: 10 pages, 7 figure

    Modelling survival and connectivity of Mnemiopsis leidyi in the south-western North Sea and Scheldt estuaries

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    Three different models were applied to study the reproduction, survival and dispersal of Mnemiopsis leidyi in the Scheldt estuaries and the southern North Sea: a high-resolution particle tracking model with passive particles, a low-resolution particle tracking model with a reproduction model coupled to a biogeochemical model, and a dynamic energy budget (DEB) model. The results of the models, each with its strengths and weaknesses, suggest the following conceptual situation: (i) the estuaries possess enough retention capability to keep an overwintering population, and enough exchange with coastal waters of the North Sea to seed offshore populations; (ii) M. leidyi can survive in the North Sea, and be transported over considerable distances, thus facilitating connectivity between coastal embayments; (iii) under current climatic conditions, M. leidyi may not be able to reproduce in large numbers in coastal and offshore waters of the North Sea, but this may change with global warming; however, this result is subject to substantial uncertainty. Further quantitative observational work is needed on the effects of temperature, salinity and food availability on reproduction and on mortality at different life stages to improve models such as used here

    Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

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    Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit. To examine the effect of such therapy on transmission, Gambian children with Plasmodium falciparum malaria were treated with standard regimens of chloroquine or pyrimethamine-sulfadoxine alone or in combination with 1 or 3 doses of artesunate. The infectivity to mosquitoes of gametocytes in peripheral blood was determined 4 or 7 days after treatment. Infection of mosquitoes was observed in all treatment groups and was positively associated with gametocyte density. The probability of transmission was lowest in those who received pyrimethamine-sulfadoxine and 3 doses of artesunate, and it was 8-fold higher in the group that received pyrimethamine-sulfadoxine alone. Artesunate reduced posttreatment infectivity dramatically but did not abolish it completely. The study raises questions about any policy to use pyrimethamine-sulfadoxine alone as the first-line treatment for malaria

    Shape oscillations in non-degenerate Bose gases - transition from the collisionless to the hydrodynamic regime

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    We investigate collective oscillations of non-degenerate clouds of Rb-87 atoms as a function of density in an elongated magnetic trap. For the low-lying M=0 monopole-quadrupole shape oscillation we measure the oscillation frequencies and damping rates. At the highest densities the mean-free-path is smaller than the axial dimension of the sample, which corresponds to collisionally hydrodynamic conditions. This allows us to cover the cross-over from the collisionless to the hydrodynamic regime. The experimental results show good agreement with theory. We also analyze the influence of trap anharmonicities on the oscillations in relation to observed temperature dependencies of the dipole and quadrupole oscillation frequencies. We present convenient expressions to quantify these effects.Comment: 10 pages, 5 figure

    Severe acute necrotizing pancreatitis associated with lipoprotein lipase deficiency in childhood

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    An 11-year-old girl with lipoprotein lipase deficiency experienced recurring episodes of abdominal pain. She initially underwent appendectomy for suspected appendicitis; however, the appendix was normal. Pancreatitis was subsequently identified as the cause of her pain

    Continuous loading of a non-dissipative atom trap

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    We study theoretically a scheme in which particles from an incident beam are trapped in a potential well when colliding with particles already present in the well. The balance between the arrival of new particles and the evaporation of particles from the trapped cloud leads to a steady-state that we characterize in terms of particle number and temperature. For a cigar shaped potential, different longitudinal and transverse evaporation thresholds can be chosen. We show that a resonance occur when the transverse evaporation threshold coincides with the energy of the incident particles. It leads to a dramatic increase in phase space density with respect to the incident beam.Comment: 7 pages, 2 figure

    Титульные страницы и содержание

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    BACKGROUND: Psychotropic drugs are prescribed to approximately 30-40% of adults with intellectual disability (ID) and challenging behaviour, despite the limited evidence of effectiveness and the potential of adverse events. AIMS: To assess the prevalence of adverse events in association with psychotropic drug use in adults with ID and challenging behaviour and to examine the relation of these adverse events with the person's quality of life. METHOD: The presence of adverse events was measured with a questionnaire that had to be filled in by the physicians of the participants. Movement disorders were measured separately with a standardised protocol. The strength of the association between adverse events and Intellectual Disability Quality of Life-16 (IDQOL-16), and daily functioning was investigated using linear regression analyses, taking into account the severity of disease (CGI-S) as potential confounder. RESULTS: Virtually all of 103 adults with ID and challenging behaviour had at least one adverse event (84.4%) and almost half had ≥3 adverse events (45.6%) across different subclasses. Using psychotropic drugs increased the prevalence of adverse events significantly. Respectively 13% of the patients without psychotropic drugs and 61% of the patients with ≥2 psychotropic drugs had ≥3 adverse events. Having adverse events had a significantly negative influence on the quality of life. CONCLUSIONS: A large majority of all patients had at least one adverse event associated with psychotropic drug use. More attention is needed for these adverse events and their negative influence on the quality of life of these patients, taking into account the lack of evidence of effectiveness of psychotropic drugs for challenging behaviour
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