100 research outputs found
Circuit Quantum Electrodynamics with a Spin Qubit
Circuit quantum electrodynamics allows spatially separated superconducting
qubits to interact via a "quantum bus", enabling two-qubit entanglement and the
implementation of simple quantum algorithms. We combine the circuit quantum
electrodynamics architecture with spin qubits by coupling an InAs nanowire
double quantum dot to a superconducting cavity. We drive single spin rotations
using electric dipole spin resonance and demonstrate that photons trapped in
the cavity are sensitive to single spin dynamics. The hybrid quantum system
allows measurements of the spin lifetime and the observation of coherent spin
rotations. Our results demonstrate that a spin-cavity coupling strength of 1
MHz is feasible.Comment: Related papers at http://pettagroup.princeton.edu
Surgical site infections after emergency hernia repair: substudy from the Management of Acutely Symptomatic Hernia (MASH) study
Introduction
Acutely symptomatic abdominal wall and groin hernias (ASH) are a common acute surgical presentation. There are limited data to guide decisions related to surgical repair technique and use of antibiotics, which can be driven by increased risk of surgical site infection (SSI) in this group. This study aims to report rates of SSI following ASH repair and explore the use of patient-reported outcome measure reporting in this setting.
Methods
An 18-week, UK-based, multicentre prospective cohort study (NCT04197271) recruited adults with ASH. This study reports operatively managed patients. Data on patient characteristics, inpatient management, quality of life, complications, and wound healing (Bluebelle score) were collected. Descriptive analyses were performed to estimate event rates of SSI and regression analysis explored the relationship between Bluebelle scores and SSI. The 30 and 90-day follow-up visits assessed complications and quality of life.
Results
The MASH study recruited 273 patients, of whom 218 were eligible for this study, 87.2 per cent who underwent open repair. Mesh was used in 123 patients (50.8 per cent). Pre- and postoperative antibiotics were given in 163 (67.4 per cent) and 28 (11.5 per cent) patients respectively. There were 26 reported SSIs (11.9 per cent). Increased BMI, incisional, femoral, and umbilical hernia were associated with higher rates of SSI (P = 0.006). In 238 patients, there was a difference in healthy utility values at 90 days between patients with and without SSI (P = 0.025). Also, when analysing 191 patients with Bluebelle scores, those who developed an SSI had higher Bluebelle values (P < 0.001).
Conclusion
SSI is frequent in repair of acutely symptomatic hernia and correlates with BMI and site of hernia
How Do Non-Democratic Regimes Claim Legitimacy? Comparative Insights from Post-Soviet Countries
The analysis using the new Regime Legitimation Expert Survey (RLES) demonstrates that non-democratic rulers in post-Soviet countries use specific combinations of legitimating claims to stay in power. Most notably, rulers claim to be the guardians of citizens' socioeconomic well-being. Second, despite recurrent infringements on political and civil rights, they maintain that their power is rule-based and embodies the will of the people, as they have been given popular electoral mandates. Third, they couple these elements with inputbased legitimation strategies that focus on nationalist ideologies, the personal capabilities and charismatic aura of the rulers, and the regime's foundational myth. Overall, the reliance on these input-based strategies is lower in the western post-Soviet Eurasian countries and very pronounced among the authoritarian rulers of Central Asia
Evaluation of the 4q32-34 Locus in European familial pancreatic cancer
Background: Familial pancreatic cancer (FPC) describes a group of families where the inheritance of pancreatic cancer is consistent with an autosomal-dominant mode of inheritance. The 4q32-34 region has been previously identified as a potential locus for FPC in a large American family
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