Gamma-radiation with E gamma 5 MeV detected from Seyfert galaxy 3C120 and region with 1" = 190 deg and b" = 20 deg

The observation of the Galaxy anticenter region in gamma-rays with E gamma = 5 / 100 MeV was made by gamma-telescope Natalya-1 in a balloon flight. The flight was performed at the ceiling 5.1 + or - 0.1 g/sq cm, magnetic cutoff being 17 GV. The description of the instrument and the analysis of the experiment conditions are given. The tracks of electron-positron pairs generated by gamma-quanta in the convertors were detected by wire spark chambers. The recorded events were classified manually by an operator using a graphic display into three classes: pairs, single and bad events. The arrival angle of gamma-quanta and their energy for selected gamma-ray events (pairs and singles) were determined through multiple scattering of pair components in the convertors. On the basis of the data obtained the celestial maps were made in gamma-rays for E sub gamma 5 MeV and E gamma 20 MeV energy ranges

Experience of eradicating parasites of laboratory rats in conventional vivarium

The purpose of the research is to test different dehelminthization schemes of laboratory rats infected with cestodes Rodentolepis nana and nematodes Syphacia muris and evaluate the significance of combined environment disinfection measures. The practical experience of eradication (helminth eradication) in animals in a conventional vivarium was described.Materials and methods. Experiments were conducted to study the efficacy of anthelmintics and administration schemes against cestode and nematode infections in laboratory rats. In the first experiment, praziquantel was used at a dose of 10 mg/kg to treat rats infected with R. nana. In the second experiment, the comparative efficacy of fenbendazole, albendazole, and pyrantel was evaluated against syphaciosis at the recommended dosages of 20, 10, and 12.5 mg/kg, respectively. Each drug was given orally, individually, twice with an interval of 7 days. The third experiment tested different schemes for treating syphaciosis with fenbendazole. One group of rats was given the drug orally individually using an esophageal tube at a dose of 20 mg/kg once a day for 7 consecutive days. Other groups were given fenbendazole daily with food for 7 days (150 mg fenbendazole per 1 kg of food). In all three experiments, all animals were divided into groups, and their cells underwent a complex of additional disinfection measures, and those kept in cages without disinfection.Results and discussion. Praziquantel showed 100% efficacy at a single dose of 10 mg/kg in R. nana therapy. In animals without additional disinfection procedures, cestode eggs were again recorded starting from day 14 after the drug administration. In the group of animals with disinfection measures, pathogens were not detected during the experiment. Double administration of fenbendazole, albendazole and pyrantel in the recommended dosages against syphaciosis did not result in eradicated nematodes in the animals. The disinfection did not affect the obtained results. Fenbendazole administered daily for 7 days ensured helminth eradication in animals. However, on day 7 after the therapy, Syphacia sp. eggs were again found in the groups that received the drug individually intragastrically through a tube, regardless of whether their cells were disinfected. The animals that received fenbendazole with food and were regularly disinfested remained free from nematodes throughout the experiment until the additional disinfection measures were cancelled. In the absence of disinfection, released helminth eggs were recorded on day 14 after therapy

Опыт освобождения лабораторных крыс от возбудителей паразитарных болезней в виварии открытого типа содержания

The purpose of the research is to test different dehelminthization schemes of laboratory rats infected with cestodes Rodentolepis nana and nematodes Syphacia muris and evaluate the significance of combined environment disinfection measures. The practical experience of eradication (helminth eradication) in animals in a conventional vivarium was described.Materials and methods. Experiments were conducted to study the efficacy of anthelmintics and administration schemes against cestode and nematode infections in laboratory rats. In the first experiment, praziquantel was used at a dose of 10 mg/kg to treat rats infected with R. nana. In the second experiment, the comparative efficacy of fenbendazole, albendazole, and pyrantel was evaluated against syphaciosis at the recommended dosages of 20, 10, and 12.5 mg/kg, respectively. Each drug was given orally, individually, twice with an interval of 7 days. The third experiment tested different schemes for treating syphaciosis with fenbendazole. One group of rats was given the drug orally individually using an esophageal tube at a dose of 20 mg/kg once a day for 7 consecutive days. Other groups were given fenbendazole daily with food for 7 days (150 mg fenbendazole per 1 kg of food). In all three experiments, all animals were divided into groups, and their cells underwent a complex of additional disinfection measures, and those kept in cages without disinfection.Results and discussion. Praziquantel showed 100% efficacy at a single dose of 10 mg/kg in R. nana therapy. In animals without additional disinfection procedures, cestode eggs were again recorded starting from day 14 after the drug administration. In the group of animals with disinfection measures, pathogens were not detected during the experiment. Double administration of fenbendazole, albendazole and pyrantel in the recommended dosages against syphaciosis did not result in eradicated nematodes in the animals. The disinfection did not affect the obtained results. Fenbendazole administered daily for 7 days ensured helminth eradication in animals. However, on day 7 after the therapy, Syphacia sp. eggs were again found in the groups that received the drug individually intragastrically through a tube, regardless of whether their cells were disinfected. The animals that received fenbendazole with food and were regularly disinfested remained free from nematodes throughout the experiment until the additional disinfection measures were cancelled. In the absence of disinfection, released helminth eggs were recorded on day 14 after therapy.Цель исследований – испытать разные схемы дегельминтизации лабораторных крыс при заражении цестодами Rodentolepis nana и нематодами Syphacia muris и оценить значение мероприятий комплексной дезинвазии среды содержания. Описан практический опыт освобождения животных (эрадикация гельминтов) в виварии открытого типа содержания.Материалы и методы. Проведены опыты по изучению эффективности антигельминтиков и схем их применения при цестодозной и нематодозной инвазиях у лабораторных крыс. В первом опыте для лечения крыс, зараженных R. nana, использовали празиквантел в дозе 10 мг/кг. Во втором опыте оценивали сравнительную эффективность фенбендазола, албендазола и пирантела при сифациозе в рекомендованных дозировках 20, 10 и 12,5 мг/кг соответственно. Каждый препарат задавали перорально, индивидуально, дважды с интервалом 7 сут. В третьем опыте испытывали разные схемы лечения сифациоза фенбендазолом. Одним группам крыс препарат задавали перорально индивидуально через пищеводный зонд в дозе 20 мг/кг один раз в день 7 сут подряд. Другим группам фенбендазол задавали ежедневно с кормом в течение 7 сут (150 мг фенбендазола на 1 кг корма). Во всех трех опытах все животные были разделены на группы, в клетках которых проводили комплекс дополнительных дезинвазионных мероприятий, и содержавшихся в клетках без дезинвазии.Результаты и обсуждение. Празиквантел показал 100%-ную эффективность при однократной даче в дозе 10 мг/кг при терапии R. nana. У животных без дополнительных дезинвазионных процедур, начиная с 14-х суток после дачи препарата, были снова зарегистрированы яйца цестод. В группе животных с дезинвазионными мероприятиями на протяжении опыта возбудители выявлены не были. Двукратное применение фенбендазола, альбендазола и пирантела в рекомендуемых дозировках при сифациозе крыс не привело к освобождению животных от нематод. Дезинвазия не повлияла на полученные результаты. Фенбендазол при ежедневном применении в течение 7 сут обеспечил освобождение животных от гельминтов. Однако, на 7-е сутки после окончания терапии яйца сифаций снова обнаруживали в группах, получавших препарат индивидуально внутрижелудочно через зонд, независимо от того, проводилась ли в их клетках дезинвазия. Животные, получавшие фенбендазол с кормом и у которых проводили регулярно дезинвазию, оставались свободными от нематод на протяжении всего опыта вплоть до отмены дополнительных дезинвазионных мероприятий. При отсутствии дезинвазии выделение яиц гельминтов зарегистрировано на 14-е сутки после окончания терапии

Soviet-Indian research of cosmic radiation by high altitude balloons

The report presents some results on the cosmic radiation intensity research carried out with the high-altitude balloons for the period of 1977-1979. The intensity of gamma-radiation with the energy above 40 MeV was measured in two balloon flights at an altitude of 4-7 g/cm2 of residual atmosphere in the vicinity of the geomagnetic equator. A temporal analysis of the intensity to discover fluctuations with periods in the range of 4-60 min was made. Quasi-periodic fluctuations of gamma-radiation intensity with 5 min periods, amplitude ∼ 20% and duration of several hours were discovered. Possible mechanisms of such fluctuation appearance are discussed. The report gives the results of measuring downward, upward and horizontal electron fluxes in the vicinity of the equator. The obtained data and the data provided by satellites are compared. The report discusses the prospects of further joint Soviet-Indian research of cosmic gamma-radiation