29,136 research outputs found
Complex structures in galaxy cluster fields: implications for gravitational lensing mass models
The distribution of mass on galaxy cluster scales is an important test of
structure formation scenarios, providing constraints on the nature of dark
matter itself. Several techniques have been used to probe the mass
distributions of clusters, sometimes yielding results which are discrepant, or
at odds with clusters formed in simulations - for example giving NFW
concentration parameters much higher than expected in the standard CDM model.
In addition, the velocity fields of some well studied galaxy clusters reveal
the presence of several structures close to the line-of-sight, often not
dynamically bound to the cluster itself. We investigate what impact such
neighbouring but unbound massive structures would have on the determination of
cluster profiles using weak gravitational lensing. Depending on its
concentration and mass ratio to the primary halo, one secondary halo close to
the line-of-sight can cause the estimated NFW concentration parameter to be
significantly higher than that of the primary halo, and also cause the
estimated mass to be biased high. Although it is difficult to envisage how this
mechanism alone could yield concentrations as high as reported for some
clusters, multiple haloes close to the line-of-sight, such as in the case of
Abell 1689, can substantially increase the concentration parameter estimate.
Together with the fact that clusters are triaxial, and that including baryonic
physics also leads to an increase in the concentration of a dark matter halo,
the tension between observations and the standard CDM model is eased. If the
alignment with the secondary structure is imprecise, then the estimated
concentration parameter can also be even lower than that of the primary halo,
reinforcing the importance of identifying structures in cluster fields.Comment: To appear in MNRAS letters, 5 pages, 3 figure
Omega-3 Fatty Acids Improve Recovery, whereas Omega-6 Fatty Acids Worsen Outcome, after Spinal Cord Injury in the Adult Rat
Spinal cord injury (SCI) is a cause of major neurological disability, and no satisfactory treatment is currently available. Evidence suggests that polyunsaturated fatty acids (PUFAs) could target some of the pathological mechanisms that underlie damage after SCI. We examined the effects of treatment with PUFAs after lateral spinal cord hemisection in the rat. The ω-3 PUFAs α-linolenic acid and docosahexaenoic acid (DHA) injected 30 min after injury induced significantly improved locomotor performance and neuroprotection, including decreased lesion size and apoptosis and increased neuronal and oligodendrocyte survival. Evidence showing a decrease in RNA/DNA oxidation suggests that the neuroprotective effect of ω-3 PUFAs involved a significant antioxidant function. In contrast, animals treated with arachidonic acid, an ω-6 PUFA, had a significantly worse outcome than controls. We confirmed the neuroprotective effect of ω-3 PUFAs by examining the effects of DHA treatment after spinal cord compression injury. Results indicated that DHA administered 30 min after spinal cord compression not only greatly increased survival of neurons but also resulted in significantly better locomotor performance for up to 6 weeks after injury.
This report shows a striking difference in efficacy between the effects of treatment with ω-3 and ω-6 PUFAs on the outcome of SCI, with ω-3 PUFAs being neuroprotective and ω-6 PUFAs having a damaging effect. Given the proven clinical safety of ω-3 PUFAs, our observations show that these PUFAs have significant therapeutic potential in SCI. In contrast, the use of preparations enriched in ω-6 PUFAs after injury could worsen outcome after SCI
Differential constraints and exact solutions of nonlinear diffusion equations
The differential constraints are applied to obtain explicit solutions of
nonlinear diffusion equations. Certain linear determining equations with
parameters are used to find such differential constraints. They generalize the
determining equations used in the search for classical Lie symmetries
Bound whispering gallery modes in circular arrays of dielectric spherical particles
Low-dimensional ordered arrays of optical elements can possess bound modes
having an extremely high quality factor. Typically, these arrays consist of
metal elements which have significantly high light absorption thus restricting
performance. In this paper we address the following question: can bound modes
be formed in dielectric systems where the absorption of light is negligible?
Our investigation of circular arrays of spherical particles shows that (1) high
quality modes in an array of 10 or more particles can be attained at least for
a refractive index , so optical materials like TiO or GaAs can
be used; (2) the most bound modes have nearly transverse polarization
perpendicular to the circular plane; (3) in a particularly interesting case of
TiO particles (rutile phase, ), the quality factor of the most
bound mode increases almost by an order of magnitude with the addition of 10
extra particles, while for particles made of GaAs the quality factor increases
by almost two orders of magnitude with the addition of ten extra particles. We
hope that this preliminary study will stimulate experimental investigations of
bound modes in low-dimensional arrays of dielectric particles.Comment: Submitted to Physical Review
The Retail FX Trader: Random Trading and the Negative Sum Game
With the internet boom of early 2000 making access to trading the Foreign Exchange (FX) market far simpler for members of the general public, the growth of 'retail' FX trading continues, with daily transaction volumes as high as $200 billion. Potential new entrants to the retail FX trading world may come from the recent UK pension deregulations, further increasing the volumes. The attraction of FX trading is that it offers high returns and whilst it has been understood that it is high-risk in nature, the rewards are seen as being commensurately high for the 'skilled and knowledgeable' trader who has an edge over other market participants. This paper analyses a number of independent sources of data and previous research, to examine the profitability of the Retail FX trader and compares the results with that of a simulated random trading models. This paper finds evidence to suggest that whilst approximately 20% of traders can expect to end up with a profitable account, around 40% might expect their account to be subject to a margin call. This paper finds a strong correlation between the overall profitability of traders and impact of the cost of the bid-ask spread, whilst finding little if any evidence that retail FX traders, when viewed as a group, are achieving results better than that from random trading
Spontaneous emergence of spatial patterns ina a predator-prey model
We present studies for an individual based model of three interacting
populations whose individuals are mobile in a 2D-lattice. We focus on the
pattern formation in the spatial distributions of the populations. Also
relevant is the relationship between pattern formation and features of the
populations' time series. Our model displays travelling waves solutions,
clustering and uniform distributions, all related to the parameters values. We
also observed that the regeneration rate, the parameter associated to the
primary level of trophic chain, the plants, regulated the presence of
predators, as well as the type of spatial configuration.Comment: 17 pages and 15 figure
Description of complex interventions: analysis of changes in reporting in randomised trials since 2002
BACKGROUND: Inadequate description of non-pharmacological complex interventions in trial publications means that they cannot be replicated or assessed for generalisability. There are published guidelines on how to describe an intervention, such as those from the CONSORT Group. However, there have been few evaluations of whether intervention reporting is improving. METHODS: We aimed to assess whether descriptions of multicomponent, non-pharmacological interventions evaluated in randomised trials are improving. To do so, we chose trials of educational and psychotherapeutic interventions to promote adherence to therapy, and compared those published between 2002 and 2007 (Time-1) with those between 2010 and 2015 (Time-2). These time periods were chosen to concord with the publication in 2008 of the CONSORT extension statement of reporting guidelines for non-pharmacological treatment which included items on intervention description. We assessed 19 items, based on the CONSORT Statement and the more recent Template for Intervention Description and Replication Checklist (TIDieR). Two reviewers independently extracted data. We created a quality score of the eight items we considered key information for replication and assessment of generalisability (setting, provider, recipient, comparator, intervention intensity, how it was conducted, existence of a manual or protocol, and detail of whether there was an assessment of fidelity). Score per item was '1' if reported adequately and '0' if not. RESULTS: Of the eligible trials, 42 were published in Time-1 and 134 published in Time-2. The trials included were published in 112 peer-reviewed journals, 52 of these journals currently require authors to follow the CONSORT Statements, while only one recommended adherence to the TIDieR. Most items of CONSORT and TIDieR were reported by more than half of the trials at both time points. Few trials reported fidelity. A large proportion of the trials did not report the existence of a manual or protocol, or what the comparator group received. We found no statistically significant improvement in the eight-item quality score (Time-1: mean 5.71 (standard deviation (SD) 1.09), Time-2: 5.87 (SD 1.28), p = 0.49). CONCLUSIONS: We found no overall evidence that reporting the specifics of multicomponent, non-pharmacological interventions is improving. Details to replicate interventions remain lacking, impairing best implementation or meaningful further research. Editorial endorsement of reporting checklists needs to be more extensive
Propagating EUV disturbances in the solar corona : two-wavelength observations
Quasi-periodic EUV disturbances simultaneously observed in 171 Å and 195 Å TRACE bandpasses propagating outwardly in a fan-like magnetic structure of a coronal active region are analysed. Time series of disturbances observed in the different bandpasses have a relatively high correlation coefficient (up to about 0.7). The correlation has a tendency to decrease with distance along the structure: this is consistent with an interpretation of the disturbances in terms of parallel-propagating slow magnetoacoustic waves. The wavelet analysis does not show a significant difference between waves observed in different bandpasses. Periodic patterns of two distinct periods: 2-3 min and 5-8 min are detected in both bandpasses, existing simultaneously and at the same distance along the loop, suggesting the nonlinear generation of the second harmonics
Self-gravitating fragmentation of eccentric accretion disks
We consider the effects of eccentricity on the fragmentation of
gravitationally unstable accretion disks, using numerical hydrodynamics. We
find that eccentricity does not affect the overall stability of the disk
against fragmentation, but significantly alters the manner in which such
fragments accrete gas. Variable tidal forces around an eccentric orbit slow the
accretion process, and suppress the formation of weakly-bound clumps. The
"stellar" mass function resulting from the fragmentation of an eccentric disk
is found to have a significantly higher characteristic mass than that from a
corresponding circular disk. We discuss our results in terms of the disk(s) of
massive stars at ~0.1pc from the Galactic Center, and find that the
fragmentation of an eccentric accretion disk, due to gravitational instability,
is a viable mechanism for the formation of these systems.Comment: 9 pages, 7 figures. Accepted for publication in Ap
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