Design of an integrated shallow water wave experiment

The experimental design and instrumentation for an integrated shallow-water surface gravity wave experiment is discussed. The experiment required the measurement of the water surface elevation, meteorological parameters, and directional spectra at a number of locations on a shallow lake. In addition, to acquire data under a wide range of conditions, an experimental period of three years was required. A system of telephone and radio modem links were installed to enable real-time monitoring of instrument performance at eight separate measurement locations on the lake. This system also enabled logging sessions to be optimized to ensure the maximum possible data return from this extended experimentIEEE Oceanic Engineering Societ

'I actually felt like I was a researcher myself.' On involving children in the analysis of qualitative paediatric research in the Netherlands

OBJECTIVES: To evaluate the feasibility of a new approach to paediatric research whereby we involved children in analysing qualitative data, and to reflect on the involvement process. SETTING: This was a single-centre, qualitative study in the Netherlands. It consisted of research meetings with individual children at home (Phase I) or group meetings at school (Phase II). In Phase I, we identified themes from a video interview during five one-on-one meetings between a child co-researcher and the adult researcher. In Phase II, during two group meetings, we explored the themes in detail using fragments from 16 interviews. PARTICIPANTS: We involved 14 school children (aged 10 to 14 years) as co-researchers to analyse children's interviews about their experience while participating in medical research. Notes were taken, and children provided feedback. A thematic analysis was performed using a framework approach. RESULTS: All co-researchers identified themes. The time needed to complete the task varied, as did the extent to which the meetings needed to be structured to improve concentration. The children rated time investment as adequate and they considered acting as co-researcher interesting and fun, adding that they had learnt new skills and gained new knowledge. The experience also led them to reflect on health matters in their own lives. The adult researchers considered the process relatively time intensive, but the project did result in a more critical assessment of their own work. CONCLUSION: The new, two-phase approach of involving children to help analyse qualitative data is a feasible research method. The novelty lies in involving children to help identify themes from original interview data, thereby limiting preselection of data by adults, before exploring these themes in detail. Videos make it easier for children to understand the data and to empathise with the interviewees, and limits time investment

Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs

Apoptosis is a physiological cell death process important for development, homeostasis and the immune defence of multicellular animals. The key effectors of apoptosis are caspases, cysteine proteases that cleave after aspartate residues. The inhibitor of apoptosis (IAP) family of proteins prevent cell death by binding to and inhibiting active caspases and are negatively regulated by IAP-binding proteins, such as the mammalian protein DIABLO/Smac. IAPs are characterized by the presence of one to three domains known as baculoviral IAP repeat (BIR) domains and many also have a RING-finger domain at their carboxyl terminus. More recently, a second group of BIR-domain-containing proteins (BIRPs) have been identified that includes the mammalian proteins Bruce and Survivin as well as BIR-containing proteins in yeasts and Caenorhabditis elegans. These Survivin-like BIRPs regulate cytokinesis and mitotic spindle formation. In this review, we describe the IAPs and other BIRPs, their evolutionary relationships and their subcellular and tissue localizations

Understanding the child-doctor relationship in research participation : a qualitative study

Funding Data collection for the Dutch interviews was funded by the University of Groningen as part of the MD/PhD program of Malou Luchtenberg. The UK data collection was supported by the National Institute for Health Research. The Academy Ter Meulen Grant provided by the Royal Netherlands Academy of Arts and Sciences enabled the research stay of ML at the Health Services Research Unit, University of Aberdeen, and supported this collaboration. The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision o submit the manuscript for publication. Acknowledgements: We want to thank all participants who were interviewed in the UK and the Netherlands. We thank Lesley Powell, who was responsible for the primary data collection in the UK. In addition, we want to show our gratitude to the Academy Medical Sciences Fund for providing Malou Luchtenberg with the Academy Ter Meulen Grant to enable her research stay at the Health Services Research Unit, University of Aberdeen that supported this collaboration.Peer reviewedPublisher PD

In-Store Interactive Advertising Screens:The Effect of Interactivity on Impulse Buying Explained by Self-Agency

Item does not contain fulltextPurpose: Physical stores are increasingly dependent on impulse visits and the impulse purchases of passers-by. Interactive advertising screens in store windows could help retailers increase impulse-visit urges and impulse-buying urges. However, the effects of interactive screens in physical surroundings have not been studied before. Therefore, this study aimed to examine the effect of interactive screens on impulse urges and gain insight into the underlying mechanism that explains the possible effect. Design/methodology/approach: An interactive screen was placed in a store window. Using three field experiments, we studied the effect of interactivity-level (high vs low) on the impulse-visit and impulse-buying urges of passers-by, and the mediating role of self-agency in these effects. Findings: Highly interactive (compared to less interactive) advertising screens in store windows positively affect impulse-visit and impulse-buying urges through self-agency. Retailers can therefore use interactive advertising screens to increase the number of impulse purchases if feelings of self-agency are activated. Originality/value: This is the first study to examine the extent to which interactive screens in a store window enhance the impulse-visit and impulse-buying urges of passers-by and the mediating factor of these effects. By conducting three field experiments, we achieved a high external validity and managed to share very reliable results owing to the replication of the findings.25 november 202118 p

Effect of unsupervised home based proprioceptive training on recurrences of ankle sprain: randomised controlled trial

Objective To evaluate the effectiveness of an unsupervised proprioceptive training programme on recurrences of ankle sprain after usual care in athletes who had sustained an acute sports related injury to the lateral ankle ligament

Exploring Effectiveness of Explanations for Appropriate Trust: Lessons from Cognitive Psychology

The rapid development of Artificial Intelligence (AI) requires developers and designers of AI systems to focus on the collaboration between humans and machines. AI explanations of system behavior and reasoning are vital for effective collaboration by fostering appropriate trust, ensuring understanding, and addressing issues of fairness and bias. However, various contextual and subjective factors can influence an AI system explanation's effectiveness. This work draws inspiration from findings in cognitive psychology to understand how effective explanations can be designed. We identify four components to which explanation designers can pay special attention: perception, semantics, intent, and user & context. We illustrate the use of these four explanation components with an example of estimating food calories by combining text with visuals, probabilities with exemplars, and intent communication with both user and context in mind. We propose that the significant challenge for effective AI explanations is an additional step between explanation generation using algorithms not producing interpretable explanations and explanation communication. We believe this extra step will benefit from carefully considering the four explanation components outlined in our work, which can positively affect the explanation's effectiveness.Comment: 2022 IEEE Workshop on TRust and EXpertise in Visual Analytics (TREX