Letter from H. L. Hille to Senator Langer Regarding Construction Bids for the Garrison Dam Project, January 31, 1955

This letter, dated January 31, 1955, from Colonel H. L. Hille of the United States (US) Army Corps of Engineers, Garrison District, to US Senator William Langer, informs Langer of the planned invitation for bids for two components of the the Garrison Dam Project taking place on the Fort Berthold Indian Reservation: lawn construction in New Town, North Dakota, on which bids will be opened on or around March 1, 1955, and the construction of the East Abutment Grout Curtain, on which bids will be opened on or about March 15, 1955. The letter includes more detailed descriptions of the two projects, and enclosed with it are advance notices for each of the two projects. Advance notices, Hille writes, have been sent to all parties who are known to be interesed in bidding on the work. See also: Letter from Senator Langer to H. L. Hille Regarding Construction Bids for the Garrison Dam Project, February 8, 1955https://commons.und.edu/langer-papers/1993/thumbnail.jp

Sensing of Fluctuating Nanoscale Magnetic Fields Using NV Centres in Diamond

New magnetometry techniques based on Nitrogen-Vacancy (NV) defects in diamond allow for the imaging of static (DC) and oscillatory (AC) nanoscopic magnetic systems. However, these techniques require accurate knowledge and control of the sample dynamics, and are thus limited in their ability to image fields arising from rapidly fluctuating (FC) environments. We show here that FC fields place restrictions on the DC field sensitivity of an NV qubit magnetometer, and that by probing the dephasing rate of the qubit in a magnetic FC environment, we are able to measure fluctuation rates and RMS field strengths that would be otherwise inaccessible with the use of DC and AC magnetometry techniques. FC sensitivities are shown to be comparable to those of AC fields, whilst requiring no additional experimental overheads or control over the sample.Comment: 5 pages, 4 figure

Letter from H. L. Hille to Representative Burdick Announcing Invitation of Bids for Lawn Construction on Fort Berthold Reservation, January 31, 1955

This letter dated January 31, 1955, from Colonel H. L. Hille to United States (US) Representative Usher Burdick, informs Burdick that the US Army Corps of Engineers proposes to issue an invitation for bids for lawn construction on the Fort Berthold Reservation. Hille details what the work will entail and where it will take place. Hille notes he has included a copy of the invitation for project bids with this letter. The included invitation for project bids gives specifics needed for a firm to submit an accurate bid and lists the required components for a submission.https://commons.und.edu/burdick-papers/1382/thumbnail.jp

Focusing in Multiwell Potentials: Applications to Ion Channels

We investigate out of equilibrium stationary distributions induced by a stochastic dichotomous noise on double and multi-well models for ion channels. Ion-channel dynamics is analyzed both through over-damped Langevin equations and master equations. As a consequence of the external stochastic noise, we prove a non trivial focusing effect, namely the probability distribution is concentrated only on one state of the multi-well model. We also show that this focusing effect, which occurs at physiological conditions, cannot be predicted by a simple master equation approach.Comment: 8 pages, 7 figure

New derivation for the equations of motion for particles in electromagnetism

We present equations of motion for charged particles using balanced equations, and without introducing explicitly divergent quantities. This derivation contains as particular cases some well known equations of motion, as the Lorentz-Dirac equations. An study of our main equations in terms of order of the interaction with the external field conduces us to the Landau-Lifshitz equations. We find that the analysis in second order show a special behavior. We give an explicit presentation up to third order of our main equations, and expressions for the calculation of general orders.Comment: 11 pages, 2 figures. Minor changes. Closer to published versio

Steady state existence of passive vector fields under the Kraichnan model

The steady state existence problem for Kraichnan advected passive vector models is considered for isotropic and anisotropic initial values in arbitrary dimension. The model includes the magnetohydrodynamic (MHD) equations, linear pressure model (LPM) and linearized Navier-Stokes (LNS) equations. In addition to reproducing the previously known results for the MHD and linear pressure model, we obtain the values of the Kraichnan model roughness parameter $\xi$ for which the LNS steady state exists.Comment: Improved text & figures, added references & other correction

Optimization of the leak conductance in the squid giant axon

We report on a theoretical study showing that the leak conductance density, \GL, in the squid giant axon appears to be optimal for the action potential firing frequency. More precisely, the standard assumption that the leak current is composed of chloride ions leads to the result that the experimental value for \GL is very close to the optimal value in the Hodgkin-Huxley model which minimizes the absolute refractory period of the action potential, thereby maximizing the maximum firing frequency under stimulation by sharp, brief input current spikes to one end of the axon. The measured value of \GL also appears to be close to optimal for the frequency of repetitive firing caused by a constant current input to one end of the axon, especially when temperature variations are taken into account. If, by contrast, the leak current is assumed to be composed of separate voltage-independent sodium and potassium currents, then these optimizations are not observed.Comment: 9 pages; 9 figures; accepted for publication in Physical Review

Biased Brownian motion in extreme corrugated tubes

Biased Brownian motion of point-size particles in a three-dimensional tube with smoothly varying cross-section is investigated. In the fashion of our recent work [Martens et al., PRE 83,051135] we employ an asymptotic analysis to the stationary probability density in a geometric parameter of the tube geometry. We demonstrate that the leading order term is equivalent to the Fick-Jacobs approximation. Expression for the higher order corrections to the probability density are derived. Using this expansion orders we obtain that in the diffusion dominated regime the average particle current equals the zeroth-order Fick-Jacobs result corrected by a factor including the corrugation of the tube geometry. In particular we demonstrate that this estimate is more accurate for extreme corrugated geometries compared to the common applied method using the spatially dependent diffusion coefficient D(x,f). The analytic findings are corroborated with the finite element calculation of a sinusoidal-shaped tube.Comment: 10 pages, 4 figure

Monte Carlo simulation for statistical mechanics model of ion channel cooperativity in cell membranes

Voltage-gated ion channels are key molecules for the generation and propagation of electrical signals in excitable cell membranes. The voltage-dependent switching of these channels between conducting and nonconducting states is a major factor in controlling the transmembrane voltage. In this study, a statistical mechanics model of these molecules has been discussed on the basis of a two-dimensional spin model. A new Hamiltonian and a new Monte Carlo simulation algorithm are introduced to simulate such a model. It was shown that the results well match the experimental data obtained from batrachotoxin-modified sodium channels in the squid giant axon using the cut-open axon technique.Comment: Paper has been revise

Non-Markovian Stochastic Resonance: three state model of ion channel gating

Stochastic Resonance in single voltage-dependent ion channels is investigated within a three state non-Markovian modeling of the ion channel conformational dynamics. In contrast to a two-state description one assumes the presence of an additional closed state for the ion channel which mimics the manifold of voltage-independent closed subconformations (inactivated ``state''). The conformational transition into the open state occurs through a domain of voltage-dependent closed subconformations (closed ``state''). At distinct variance with a standard two-state or also three-state Markovian approach, the inactivated state is characterized by a broad, non-exponential probability distribution of corresponding residence times. The linear response to a periodic voltage signal is determined for arbitrary distributions of the channel's recovery times. Analytical results are obtained for the spectral amplification of the applied signal and the corresponding signal-to-noise ratio. Alternatively, these results are also derived by use of a corresponding two-state non-Markovian theory which is based on driven integral renewal equations [I. Goychuk and P. Hanggi, Phys. Rev. E 69, 021104 (2004)]. The non-Markovian features of stochastic resonance are studied for a power law distribution of the residence time-intervals in the inactivated state which exhibits a large variance. A comparison with the case of bi-exponentially distributed residence times possessing the same mean value, i.e. a simplest non-Markovian two-state description, is also presented