111 research outputs found
The Wide-field Infrared Survey Explorer (WISE): Mission Description and Initial On-orbit Performance
The all sky surveys done by the Palomar Observatory Schmidt, the European
Southern Observatory Schmidt, and the United Kingdom Schmidt, the InfraRed
Astronomical Satellite and the 2 Micron All Sky Survey have proven to be
extremely useful tools for astronomy with value that lasts for decades. The
Wide-field Infrared Survey Explorer is mapping the whole sky following its
launch on 14 December 2009. WISE began surveying the sky on 14 Jan 2010 and
completed its first full coverage of the sky on July 17. The survey will
continue to cover the sky a second time until the cryogen is exhausted
(anticipated in November 2010). WISE is achieving 5 sigma point source
sensitivities better than 0.08, 0.11, 1 and 6 mJy in unconfused regions on the
ecliptic in bands centered at wavelengths of 3.4, 4.6, 12 and 22 microns.
Sensitivity improves toward the ecliptic poles due to denser coverage and lower
zodiacal background. The angular resolution is 6.1, 6.4, 6.5 and 12.0
arc-seconds at 3.4, 4.6, 12 and 22 microns, and the astrometric precision for
high SNR sources is better than 0.15 arc-seconds.Comment: 22 pages with 19 included figures. Updated to better match the
accepted version in the A
Genes Associated with 2-Methylisoborneol Biosynthesis in Cyanobacteria: Isolation, Characterization, and Expression in Response to Light
The volatile microbial metabolite 2-methylisoborneol (2-MIB) is a root cause of taste and odor issues in freshwater. Although current evidence suggests that 2-MIB is not toxic, this compound degrades water quality and presents problems for water treatment. To address these issues, cyanobacteria and actinomycetes, the major producers of 2-MIB, have been investigated extensively. In this study, two 2-MIB producing strains, coded as Pseudanabaena sp. and Planktothricoids raciborskii, were used in order to elucidate the genetic background, light regulation, and biochemical mechanisms of 2-MIB biosynthesis in cyanobacteria. Genome walking and PCR methods revealed that two adjacent genes, SAM-dependent methyltransferanse gene and monoterpene cyclase gene, are responsible for GPP methylation and subsequent cyclization to 2-MIB in cyanobacteria. These two genes are located in between two homologous cyclic nucleotide-binding protein genes that may be members of the Crp-Fnr regulator family. Together, this sequence of genes forms a putative operon. The synthesis of 2-MIB is similar in cyanobacteria and actinomycetes. Comparison of the gene arrangement and functional sites between cyanobacteria and other organisms revealed that gene recombination and gene transfer probably occurred during the evolution of 2-MIB-associated genes. All the microorganisms examined have a common origin of 2-MIB biosynthesis capacity, but cyanobacteria represent a unique evolutionary lineage. Gene expression analysis suggested that light is a crucial, but not the only, active regulatory factor for the transcription of 2-MIB synthesis genes. This light-regulated process is immediate and transient. This study is the first to identify the genetic background and evolution of 2-MIB biosynthesis in cyanobacteria, thus enhancing current knowledge on 2-MIB contamination of freshwater
Biomarkers can predict potential clinical responders to DIMS0150 a toll-like receptor 9 agonist in ulcerative colitis patients
Fermentation-derived aroma compounds in varietal young wines from South Africa
The original publication is available at http://www.sasev.org/.The volatile composition of 925 single cultivar young Sauvignon blanc, Chardonnay, Pinotage, Merlot, Shiraz and Cabernet Sauvignon wines of vintages 2005 to 2007, was determined using gas chromatography-flame ionisation detection. Compositional data were compared to published data on young wines from South Africa and other countries. South African young wines analysed in this study had a largely similar volatile composition to that reported in the literature. Significant between-vintage and between-cultivar differences were observed in the volatile composition of the wines investigated in this study. The concentration ranges of four compounds in red wines, hexanol, propanol, diethyl succinate and ethyl lactate, and four compounds in white wines, 2-phenylethanol, hexanoic acid, isoamyl acetate and propanol, were not influenced by vintage effects. This finding was interpreted as the first indication that typical concentration ranges for some aroma compounds can be established for South African young cultivar wines. A trend was observed in the white wines that the alcohols and their respective acetate esters, as well as fatty acids and their ethyl esters, were responsible for the vintage-related effects. Differences in volatile composition between Chardonnay and Sauvignon blanc wines could also largely be explained on the same basis. Classification models were established to discriminate between individual red wine cultivars and between the two white wine cultivars and correct classification rates of respectively, 79 % and 85 % were achieved.Publishers' versio
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Cryogen system analysis for the Mirror Fusion Test Facility. Final report
The Mirror Fusion Test Facility being designed and constructed at the Lawrence Livermore Laboratory requires a liquid helium liquefaction, storage, distribution, and recovery system and a liquid nitrogen storage and distribution system. To provide a powerful analytical tool to aid in the design evolution of this system through hardware, a thermodynamic fluid flow model was developed. This final report defines the cryogen system that was analyzed (consisting of the LHe subsystem, the GHe recovery subsystem and the LN/sub 2/ subsystem). It details the program assumptions, the theoretical basis for the analysis and limitations of the output. Several parametric runs were performed to illustrate the use of the program. Special detailed analyses were also performed on components such as the recuperator in the helium gas recovery system
Validation of two Napping techniques as rapid sensory screening tools for high alcohol products.
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