Single-Walled Carbon Nanotubes as Shadow Masks for Nanogap Fabrication

We describe a technique for fabricating nanometer-scale gaps in Pt wires on insulating substrates, using individual single-walled carbon nanotubes as shadow masks during metal deposition. More than 80% of the devices display current-voltage dependencies characteristic of direct electron tunneling. Fits to the current-voltage data yield gap widths in the 0.8-2.3 nm range for these devices, dimensions that are well suited for single-molecule transport measurements

Hamiltonian formalism of the DNLS equation with nonvanished boundary value

Hamiltonian formalism of the DNLS equation with nonvanishing boundary value is developed by the standard procedure.Comment: 11 page

U.S. HOUSEHOLD CONSUMPTION OF FRESH FRUITS

This study uses the 1987-88 U.S. Department of Agriculture Nationwide Food Consumption Survey data to analyze the impacts of income, prices, and selected socioeconomic characteristics on household consumption of fresh fruits. Results suggest that fresh fruits are considered economic necessities, with own prices significantly influencing consumption. Cross-price effects are generally weak and insignificant, but the number of adults in the age group 18-64 is an important determinant of household consumption of fresh fruits. While nutrition information and household savings have significant, positive influences on most fresh fruit consumption, the presence of a working wife has a significant and negative influence.Food Consumption/Nutrition/Food Safety,

Organic Price Premiums Paid for Fresh Tomatoes and Apples by U.S. Households: Evidence from Nielsen Homescan Data

Using multivariate regression on data composed of prices, produce characteristics, demographics, and interactions, this study investigates organic price premiums paid by U.S. consumers for fresh tomatoes and apples, two of the top organic produce sellers, and identifies factors explaining variation in price premiums. The econometric problem of each buyer having multiple records in the purchase data is addressed in the estimation procedure.Consumer/Household Economics, Food Consumption/Nutrition/Food Safety,

Secondary Rayleigh-Taylor type Instabilities in the Reconnection Exhaust Jet as a Mechanism for Supra-Arcade Downflows

Supra-arcade downflows (hereafter referred to as SADs) are low-emission, elongated, finger-like features usually observed in active-region coronae above post-eruption flare arcades. Observations exhibit downward moving SADs intertwined with bright upward moving spikes. Whereas SADs are dark voids, spikes are brighter, denser structures. Although SADs have been observed for decades, the mechanism of formation of SADs remains an open issue. In our three-dimensional resistive magnetohydrodynamic simulations, we demonstrate that secondary Rayleigh-Taylor type instabilities develop in the downstream region of a reconnecting current sheet. The instability results in the formation of low-density coherent structures that resemble SADs, and high-density structures that appear to be spike-like. Comparison between the simulation results and observations suggests that secondary Rayleigh-Taylor type instabilities in the exhaust of reconnecting current sheets provide a plausible mechanism for observed SADs and spikes

A crucial sequence for transglutaminase type 2 extracellular trafficking in renal tubular epithelial cells lies in its N-terminal {beta}-sandwich domain

Transglutaminase type 2 (TG2) catalyzes the formation of an -( -glutamyl)-lysine isopeptide bond between adjacent peptides or proteins including those of the extracellular matrix (ECM). Elevated extracellular TG2 leads to accelerated ECM deposition and reduced clearance that underlie tissue scarring and fibrosis. The extracellular trafficking of TG2 is crucial to its role in ECM homeostasis; however, the mechanism by which TG2 escapes the cell is unknown as it has no signal leader peptide and therefore cannot be transported classically. Understanding TG2 transport may highlight novel mechanisms to interfere with the extracellular function of TG2 as isoform-specific TG2 inhibitors remain elusive. Mammalian expression vectors were constructed containing domain deletions of TG2. These were transfected into three kidney tubular epithelial cell lines, and TG2 export was assessed to identify critical domains. Point mutation was then used to highlight specific sequences within the domain required for TG2 export. The removal of -sandwich domain prevented all TG2 export. Mutations of Asp94 and Asp97 within the N-terminal -sandwich domain were identified as crucial for TG2 externalization. These form part of a previously identified fibronectin binding domain (88WTATVVDQQDCTLSLQLTT106). However, siRNA knockdown of fibronectin failed to affect TG2 export. The sequence 88WTATVVDQQDCTLSLQLTT106 within the -sandwich domain of TG2 is critical to its export in tubular epithelial cell lines. The extracellular trafficking of TG2 is independent of fibronectin