Становление социального заказа на педагогов в истории русского образования

Introduction. The first state educational institution for teacher’s training was the teachers’ seminary established in 1783. However, the teaching profession appeared in Russia long before that and was supported by social request. This fact builds questions about transformations of public expectations in relation to teachers, i.e. about the history of the social order to teachers. That order had not been realized and reflected in some documents for a long time, but its influence on education in Russia can be clearly observed already in the 17th century. Purpose setting. The article attempts to determine features of its becoming. Methodology of the study. The research is based on a large layer of literature, on the principles of dialectics and historicism, and uses comparative historical analysis, deduction, culturomics, content analysis, statistics and other theoretical methods. Results. Features of forming of a social order to teachers in the 17th and 18th centuries are identified and specified. The factors and conditions of its forming in the specified historical period are characterized; its structural components were determined, also patterns of changes in the social order for teachers and its actualization time were detected. Conclusion. In the 17th century, there was an order for teachers in the Russian Tsardom, the subject of which was the church, but partly also the state and townspeople. The state imposed requirements on teacher’s work, regulating some aspects of school organizing. The emerging in those times trend of transition from religious characteristics of the teacher to professional ones finally took shape at the beginning of the 18th century, when the state order for teachers had been formed. By the middle of the century, the image of the teacher had radically changed, and there were requirements of professionalism in the being taught science and of positive personal characteristics, which found its place in organizing of the first teachers’ seminary: the order for teacher’s methodological training began thanks to it. Patterns of formation of a social order to teachers (society always has high expectations from either professional or personal characteristics of the teacher; during periods of social conflicts and changes the requirements for his personal characteristics are actualized; that transfer depends on social stability) confirm that clearly it depends on historical periods and socio-political conditions.Введение. Первым государственным образовательным учреждением по подготовке учителей стала учительская семинария, созданная в 1783 г. Однако учительская профессия возникла в России задолго до этого и поддерживалась запросом со стороны общества. Это вызывает вопросы о трансформациях общественных ожиданий в отношении учителей – об истории социального заказа на педагогов. Социальный заказ на педагогов долго не был осознан и отражен в регламентирующей документации, его влияние на организацию образования в России можно отчетливо наблюдать уже с XVII в. В статье предпринимается попытка определить особенности его становления. Методика и методология исследования. В основе исследования ‒ большой пласт литературы, оно строится на принципах диалектики и историзма, использовании сравнительно-исторического анализа, дедукции, культуромики, контент-анализа, статистики и других методов теоретического осмысления. Результаты. Выявлены и конкретизированы особенности становления социального заказа педагогам в XVII‒XVIII вв. Охарактеризованы факторы и условия его формирования в указанный исторический период, определены его структурные компоненты, обнаружены закономерности изменения социального заказа на педагогов, время его актуализации. Выводы. В XVII в. в Русском царстве возник заказ на педагогов, субъектом которого выступала церковь, отчасти – государство и горожане. Государство предъявляло требования к работе учителей, регламентируя некоторые аспекты организации школ. Наметившаяся тогда тенденция перехода от духовных характеристик педагога к профессиональным окончательно оформилась в начале XVIII в., когда был определен государственный заказ на учителей. К середине века образ учителя кардинально изменен, к нему предъявляются требования профессионализма в преподаваемой науке и положительных личностных характеристик, что нашло отражение при организации учительской семинарии; с нее начался заказ на методическую подготовку педагога. Закономерности формирования социального заказа учителям (общество всегда обладает повышенными ожиданиями или к профессиональным, или к личностным характеристикам педагога; в периоды социальных конфликтов и перемен актуализируются требования к личности; перевес зависит от социальной стабильности) подтверждают его обусловленность историческим периодом и социально-политическими условиями

Risk factors for external genital endometriosis

One of the most common forms of violation of the reproductive system of a woman is endometriosis. It is assumed that the genetic predisposition and environmental factors are closely related to the development of endometriosis. However, despite the high prevalence of endometriosis among women of reproductive age, the risk factors or markers for the development of the disease remain largely unknown. The aim of the study was to identify risk factors for external genital endometriosis. Materials and methods. Study design: retrospective case-control. The study included 154 women. Group I included 77 women with histologically verified external genital endometriosis. Group II consisted of 77 women without endometriosis, who underwent endoscopic surgery due to various diseases of the pelvic organs. Results. The results of the study showed that the most significant risk factors for endometriosis are the early onset of menarche (< 11 years), a shortened menstrual cycle with prolonged menstruation, active and passive smoking, the presence of furnace heating and uterine fibroids, a family history of breast cancer. Typical complaints of patients with endometriosis are pelvic pain, dysmenorrhea and dyspareunia. Conclusions. Further studies are needed to study the significance of these factors in the diagnosis of endometriosis and the understanding of its etiology

The action of bacillus' metzinc metalloproteinase on cultured animal cell lines

Microbial enzymes with high activity are increasingly used in medical practice in development of drugs for treatment of burn injuries, diseases of gastrointestinal tract, as well as in systemic enzyme therapy. One of crucial requirements for such drugs is the absence of toxicity, both on cellular and organism levels. The aim of the present study was to evaluate cytotoxic effect of Bacillus pumilus metzinc metalloproteinase on animal cell lines. Cytological changes in LEK, Vero and PK-15 cell lines were observed after cell treatment with 155 μ/ml enzyme. However, lower enzyme concentrations - 75 and 15 μ/ml did not show any toxicity

Revision of an Optical Engineering Lecture Based on students\u27 Evaluation of University Teaching

This article describes the revision of a lecture in optical engineering based on an evaluation of university teaching by students. Although this evaluation method is widely accepted and investigated, only few practically oriented reports on the deduction of teaching improvements from the evaluation\u27s results on lectures are available. Our approach is the analysis of evaluation results by applying the principles of the explorative factor analysis (EFA). The changes that were derived from this analysis were mainly focused on a revision of the course structure and its presentation style.Finally, the impact of the modifications was measured by the evaluation of the lecture after the completed revision. The later evaluation showed improvements in all intended areas of interests illustrating the benefit of thorough revisions for the quality of teaching

Rigidity-dependent cosmic ray energy spectra in the knee region obtained with the GAMMA experiment

On the basis of the extensive air shower (EAS) data obtained by the GAMMA experiment, the energy spectra and elemental composition of the primary cosmic rays are derived in the 1-100 PeV energy range. The reconstruction of the primary energy spectra is carried out using an EAS inverse approach in the framework of the SIBYLL2.1 and QGSJET01 interaction models and the hypothesis of power-law primary energy spectra with rigidity-dependent knees. The energy spectra of primary H, He, O-like and Fe-like nuclei obtained with the SIBYLL interaction model agree with corresponding extrapolations of the balloon and satellite data to ~1 PeV energies. The energy spectra obtained from the QGSJET model show a predominantly proton composition in the knee region. The rigidity-dependent knee feature of the primary energy spectra for each interaction model is displayed at the following rigidities: ~2.5+/-0.2 PV (SIBYLL) and ~3.1-4.2 PV (QGSJET). All the results presented are derived taking into account the detector response, the reconstruction uncertainties of the EAS parameters, and fluctuations in the EAS development.Comment: 28 pages, 18 figures, accepted for publication in Astroparticle Physic

Occlusion of rectal arteries in the treatment of recurrent hemorrhoidal disease after transanal surgical interventions

The article presents data on variant X-ray anatomy of the superior rectal artery and types of arterial architectonics of the rectum. The causes of recurrent hemorrhoidal disease after traditional transanal surgical interventions are highlighted. The possibilities of endovascular occlusion of rectal arteries in the treatment of relapses of chronic hemorrhoids are shown. Its technical variants are given depending on the number of hemorrhoidal arteries and types of arterial architectonics of the rectum.Over a 2-year period, clinical results of endovascular occlusion of hemorrhoidal arteries were evaluated in 11 patients with relapse of the disease after various transanal interventions: after latex ligation of internal hemorrhoids – in 5, transanal desarterization of internal hemorrhoids with mucopexia – in 4, hemorrhoidectomy – in 2. The average age of patients was 44.2 ± 12.5 years. Men – 5, women – 6. Superselective occlusion of the target hemorrhoidal branches of the upper rectal artery was performed with EmboGold (Merit Medical) microparticles, 500–700/300–500 mkm in size. Immediate results: cessation of bleeding on the first day – in 4 patients, after 3 days – in 5, after 7 days – in 2. Terms of hospitalization – 1 day, disability – 4.3 ± 0.7 days. Long-term results (from 1 to 2 years) were observed in all 11 patients. The course is relapse-free.As an illustration, a clinical case is presented – successful treatment of a patient with recurrent hemorrhoidal disease by endovascular occlusion of hemorrhoidal arteries after five traditional transanal surgical interventions: sclerosing, ligation, dearterization of internal hemorrhoids, dearterization of internal hemorrhoids with mucopexia, removal of external hemorrhoids. Within 3 months after endovascular occlusion – complete regression of all symptoms of hemorrhoidal disease. According to the questionnaire (after 1 and 2 years) there is no relapse of the disease, the patient is subjectively satisfied with the endovascular treatment

The importance of pathogenicity factors of some Streptococcus spp. and Klebsiella spp. in determining their etiological role in the inflammatory processes of the respiratory tract

Together with the known pathogens of inflammatory processes of the respiratory tract in clinical practice are often found representatives of Streptococcus and Klebsiella, previously considered commensals of the mucous membranes of the upper respiratory tract. The exchange of genetic information facilitates the transfer of virulence factors between strains not only within the species but also within the genus. In such cases, the acquisition of virulence genes by nonpathogenic species from representatives of pathogenic species contributes to the manifestation of previously not typical properties. Therefore, the aim of the research was to study the virulence of opportunistic Streptococcus spp. and Klebsiella spp. in inflammatory processes of the respiratory tract and substantiate their etiological role in the development of the disease. We studied 220 strains of Streptococcus spp. and 97 strains of Klebsiella spp., isolated from patients with inflammatory processes in the respiratory tract and from healthy individuals. Strains of Streptococcus spp. were investigated for the presence of virulence genes: sagA, lmb, fapl, ply, lytA. Strains of Klebsiella spp. were examined for the presence of virulence genes: MrkD, magA, kfu. The phenotypic marker of lmb gene expression in Streptococcus and MrkD gene in Klebsiella was the indicator of adhesion of isolated strains to buccal epithelial cells. Expression of the fapl gene was evaluated in a phenotypic biofilm formation test. In individuals with upper respiratory tract inflammation, the most common types of strepto -cocci were: S. mitis, S. anginosus, and S. oralis. Strains of these species isolated from inflammatory processes in the upper respiratory tract had 2—4 times greater adhesiveness than strains isolated from healthy individuals. Phenotypic determination of the ability to biofilm formation showed that strains of Streptococcus containing the fapl gene formed a dense biofilm in contrast to strains without the fapl gene. K. oxytoca strains isolated from people with sinusitis had mrkd, magA, and kfu virulence genes that are characteristic of K. pneumoniae strains. In phenotypic tests, it was found that the value of the adhesion index in K. oxytoca strains isolated from patients is 4 times higher than in strains of this species isolated from healthy individuals. Thus, to confirm the etiological role of an opportunistic microorganism in the development of the infectious process, it is necessary to be guided by data on the genetic and phenotypic markers of virulence of the isolated strain

Features of Muon Arrival Time Distributions of High Energy EAS at Large Distances From the Shower Axis

In view of the current efforts to extend the KASCADE experiment (KASCADE-Grande) for observations of Extensive Air Showers (EAS) of primary energies up to 1 EeV, the features of muon arrival time distributions and their correlations with other observable EAS quantities have been scrutinised on basis of high-energy EAS, simulated with the Monte Carlo code CORSIKA and using in general the QGSJET model as generator. Methodically various correlations of adequately defined arrival time parameters with other EAS parameters have been investigated by invoking non-parametric methods for the analysis of multivariate distributions, studying the classification and misclassification probabilities of various observable sets. It turns out that adding the arrival time information and the multiplicity of muons spanning the observed time distributions has distinct effects improving the mass discrimination. A further outcome of the studies is the feature that for the considered ranges of primary energies and of distances from the shower axis the discrimination power of global arrival time distributions referring to the arrival time of the shower core is only marginally enhanced as compared to local distributions referring to the arrival of the locally first muon.Comment: 24 pages, Journal Physics G accepte

Cardiac Hypertrophy Involves Both Myocyte Hypertrophy and Hyperplasia in Anemic Zebrafish

Background: An adult zebrafish heart possesses a high capacity of regeneration. However, it has been unclear whether and how myocyte hyperplasia contributes to cardiac remodeling in response to biomechanical stress and whether myocyte hypertrophy exists in the zebrafish. To address these questions, we characterized the zebrafish mutant tr265/tr265, whose Band 3 mutation disrupts erythrocyte formation and results in anemia. Although Band 3 does not express and function in the heart, the chronic anemia imposes a sequential biomechanical stress towards the heart. Methodology/principal findings: Hearts of the tr265/tr265 Danio rerio mutant become larger than those of the sibling by week 4 post fertilization and gradually exhibit characteristics of human cardiomyopathy, such as muscular disarray, re-activated fetal gene expression, and severe arrhythmia. At the cellular level, we found both increased individual cardiomyocyte size and increased myocyte proliferation can be detected in week 4 to week 12 tr265/tr265 fish. Interestingly, all tr265/tr265 fish that survive after week-12 have many more cardiomyocytes of smaller size than those in the sibling, suggesting that myocyte hyperplasia allows the long-term survival of these fish. We also show the cardiac hypertrophy process can be recapitulated in wild-type fish using the anemia-inducing drug phenylhydrazine (PHZ). Conclusions/significance: The anemia-induced cardiac hypertrophy models reported here are the first adult zebrafish cardiac hypertrophy models characterized. Unlike mammalian models, both cardiomyocyte hypertrophy and hyperplasia contribute to the cardiac remodeling process in these models, thus allowing the effects of cardiomyocyte hyperplasia on cardiac remodeling to be studied. However, since anemia can induce effects on the heart other than biomechanical, non-anemic zebrafish cardiac hypertrophy models shall be generated and characterized

Atmospheric Muon Flux at Sea Level, Underground, and Underwater

The vertical sea-level muon spectrum at energies above 1 GeV and the underground/underwater muon intensities at depths up to 18 km w.e. are calculated. The results are particularly collated with a great body of the ground-level, underground, and underwater muon data. In the hadron-cascade calculations, the growth with energy of inelastic cross sections and pion, kaon, and nucleon generation in pion-nucleus collisions are taken into account. For evaluating the prompt muon contribution to the muon flux, we apply two phenomenological approaches to the charm production problem: the recombination quark-parton model and the quark-gluon string model. To solve the muon transport equation at large depths of homogeneous medium, a semi-analytical method is used. The simple fitting formulas describing our numerical results are given. Our analysis shows that, at depths up to 6-7 km w. e., essentially all underground data on the muon intensity correlate with each other and with predicted depth-intensity relation for conventional muons to within 10%. However, the high-energy sea-level data as well as the data at large depths are contradictory and cannot be quantitatively decribed by a single nuclear-cascade model.Comment: 47 pages, REVTeX, 15 EPS figures included; recent experimental data and references added, typos correcte