26 research outputs found
Electrochemical reduction of cobalt(II), palladium(II), and copper(II) chelates with ?-hydroxylamine oximes at the dropping mercury electrode
Prevalence and Symptom Characteristics of Irritable Bowel Syndrome Among Bronchial Asthma Patients in Pakistan
Solubility of tetraphenylborates of the alkali metals and ammonium in acetone-water mixtures at 25�
Unusual morphological damage of purkinje cells following postnatal BrdU administration in the cerebellar cortex of mouse
COPD immunopathology
The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette smoking. In the last quarter of the century, the analysis of specimens obtained from the lower airways of COPD patients compared with those from a control group of age-matched smokers with normal lung function has provided novel insights on the potential pathogenetic role of the different cells of the innate and acquired immune responses and their pro/anti-inflammatory mediators and intracellular signalling pathways, contributing to a better knowledge of the immunopathology of COPD both during its stable phase and during its exacerbations. This also has provided a scientific rationale for new drugs discovery and targeting to the lower airways. This review summarises and discusses the immunopathology of COPD patients, of different severity, compared with control smokers with normal lung function