Preliminary designs for X-ray source modifications for the Marshall Space Flight Center's X-ray calibration facility

The objective of this investigation is to develop preliminary designs for modifications to the X-ray source of the MSFC X-Ray Calibration Facility. Recommendations are made regarding: (1) the production of an unpolarized X-ray beam, (2) modification of the source to provide characteristic X-rays with energies up to 40 keV, and (3) addition of the capability to calibrate instruments in the extreme ultraviolet wavelength region

Neglected tropical diseases in the genomics era: re-evaluating the impact of new drugs and mass drug administration.

Simon Croft answers Genome Biology's questions on ways to approach neglected tropical diseases in the genomics era, including re-evaluating the impact of new drugs and mass drug administration

Still in My Mind: An Exploration of Practice-led Experimental Research in Progress

The author, an Indigenous woman of mixed heritage, aGurindji/Malgnin/Mudpurra person on her father’s side discusses her practice-led research project, Still in My Mind: Gurindji Experience, Location and Visuality. This project draws inspiration from the words of revered Gurindji elder Vincent Lingiari, profoundly reiterating a deep commitment to his Gurindji/Malgnin peoples and their homelands on Wave Hill in the Northern Territory

Leishmaniasis: new approaches to disease control.

The leishmaniases afflict the world's poorest populations. Among the two million new cases each year in the 88 countries where the disease is endemic (fig 1), it is estimated that 80% earn less than $2 a day. Human infections with Leishmania protozoan parasites, transmitted via the bite of a sandfly, cause visceral, cutaneous, or mucocutaneous leishmaniasis. The global burden of leishmaniasis has remained stable for some years, causing 2.4 million disability adjusted life years (DALYs) lost and 59 000 deaths in 2001. Neglected by researchers and funding agencies, leishmaniasis control strategies have varied little for decades, but in recent years there have been exciting advances in diagnosis, treatment, and prevention. These include an immunochromatographic dipstick for diagnosing visceral leishmaniasis; the licensing of miltefosine, the first oral drug for visceral leishmaniasis; and evidence that the incidence of zoonotic visceral leishmaniasis in children can be reduced by providing dogs with deltamethrin collars. There is also hope that the first leishmaniasis vaccine will become available within a decade. Here we review these developments and identify priorities for research

Copyrights-Liabilty of Store Owner for Sale of Infringing Phonograph Records by Concessionaire

Defendant H. L. Green Company licensed defendant Jalen Amusement Company as concessionaire of the record departments in twenty-three of its stores. The licensing agreement required Jalen\u27s employees to follow all Green\u27s rules and regulations and empowered Green to discharge any employee found to be conducting himself improperly. The gross receipts of the record department were collected by Green, Jalen receiving only the amount remaining after deductions for the license fee, salaries, and taxes. Although Jalen ordered and paid for the records and its employees made all the sales, record purchasers were unaware of Jalen\u27s autonomy in the record department. Plaintiff, copyright proprietor of several musical compositions, alleged that Jalen had manufactured recordings of these compositions in violation of section 101(e) of the Copyright Act. Plaintiff also alleged that Green had violated the same section by contributing to and participating actively in the sale of these recordings. The trial court found Jalen liable but dismissed the complaint as to Green. On appeal from the order dismissing Green, held, reversed and remanded for determination of damages. A concession licensor having control over the employees and benefiting proportionately from the sales of a licensee-vendor is liable in the amount of the statutory damages assessed for the sale of records infringing on copyrighted musical compositions. Shapiro, Bernstein b Co. v. H. L. Green Co., 316 F.2d 304 (2d Cir. 1963)

Predictive learning, prediction errors, and attention: evidence from event-related potentials and eye tracking

Prediction error (‘‘surprise’’) affects the rate of learning: We learn more rapidly about cues for which we initially make incorrect predictions than cues for which our initial predictions are correct. The current studies employ electrophysiological measures to reveal early attentional differentiation of events that differ in their previous involvement in errors of predictive judgment. Error-related events attract more attention, as evidenced by features of event-related scalp potentials previously implicated in selective visual attention (selection negativity, augmented anterior N1). The earliest differences detected occurred around 120 msec after stimulus onset, and distributed source localization (LORETA) indicated that the inferior temporal regions were one source of the earliest differences. In addition, stimuli associated with the production of prediction errors show higher dwell times in an eyetracking procedure. Our data support the view that early attentional processes play a role in human associative learning

Interacting Factors Associated With Adult Male Drowning In New Zealand

Objectives: i) to identify factors that contribute to the global trend of the higher incidence of male drowning relative to females, and; ii) to explore relationships between such factors from mortality data in New Zealand. Methods: Drownings from 1983 to 2012 were examined for: Age, Ethnicity, Site, Activity, Buoyancy and Alcohol. Conditional frequency tables presented as mosaic plots were used to assess the interactions of these factors. Results: Alcohol was involved in a high proportion of Accidental Immersion drownings (61%) and was highest for males aged 20-24 years. When alcohol was involved there were proportionally more incidences where a life jacket was Available But Not Worn and less incidences where a life jacket was Worn. Many 30-39 year old males drowned during underwater activities (e.g., snorkeling, diving). Older men (aged +55 years old) had a high incidence of drowning while boating. Different ethnicities were over-represented in different age groups (Asian men aged 25-29, and European men aged 65-74) and when involved in different activities. Conclusions: Numerous interacting factors are responsible for male drownings. In New Zealand, drowning locations and activities differ by age and ethnicity which require targeted intervention strategies

Affordance boundaries are defined by dynamic capabilities of Parkour athletes in dropping from various heights

Available behaviors are determined by the fit between features of the individual and reciprocal features of the environment. Beyond some critical boundary certain behaviors become impossible causing sudden transitions from one movement pattern to another. Parkour athletes have developed multiple movement patterns to deal with their momentum during landing. We were interested in whether drop distance would cause a sudden transition between a two-footed (precision) landing and a load-distributing roll and whether the transition height could be predicted by dynamic and geometric characteristics of individual subjects. Kinematics and ground reaction forces were measured as Parkour athletes stepped off a box from heights that were incrementally increased or decreased from 0.6 to 2.3 m. Individuals were more likely to roll from higher drops; those with greater body mass and less explosive leg power, were more likely to transition to a roll landing at a lower height. At some height a two-footed landing is no longer feasible but for some athletes this height was well within the maximum drop height used in this study. During low drops the primary task constraint of managing momentum could be achieved with either a precision landing or a roll. This meant that participants were free to select their preferred landing strategy, which was only partially influenced by the physical demands of the task. However, athletes with greater leg power appeared capable of managing impulse absorption through a leg mediated strategy up to a greater drop height