Vortex structure in exponentially shaped Josephson junctions

We report the numerical calculations of the static vortex structure and critical curves in exponentially shaped long Josephson junctions for in-line and overlap geometries. Each solution of the corresponding boundary value problem is associated with the Sturm-Liouville problem whose minimal eigenvalue allows to make a conclusion about the stability of the vortex. The change in width of the junction leads to the renormalization of the magnetic flux in comparison to the case of a linear one-dimensional model. We study the influence of the model's parameters and, particularly, the shape parameter on the stability of the states of the magnetic flux. We compare the vortex structure and critical curves for the in-line and overlap geometries. Our numerically constructed critical curve of the Josephson junction matches well with the experimental one.Comment: 8 pages, 10 figures, NATO Advanced Research Workshop on "Vortex dynamics in superconductors and other complex systems" Yalta, Crimea, Ukraine, 13-17 September 200

Relativistic graphene ratchet on semidisk Galton board

Using extensive Monte Carlo simulations we study numerically and analytically a photogalvanic effect, or ratchet, of directed electron transport induced by a microwave radiation on a semidisk Galton board of antidots in graphene. A comparison between usual two-dimensional electron gas (2DEG) and electrons in graphene shows that ratchet currents are comparable at very low temperatures. However, a large mean free path in graphene should allow to have a strong ratchet transport at room temperatures. Also in graphene the ratchet transport emerges even for unpolarized radiation. These properties open promising possibilities for room temperature graphene based sensitive photogalvanic detectors of microwave and terahertz radiation.Comment: 4 pages, 4 figures. Research done at Quantware http://www.quantware.ups-tlse.fr/. More detailed analysis is give

Directed motion of domain walls in biaxial ferromagnets under the influence of periodic external magnetic fields

Directed motion of domain walls (DWs) in a classical biaxial ferromagnet placed under the influence of periodic unbiased external magnetic fields is investigated. Using the symmetry approach developed in this article the necessary conditions for the directed DW motion are found. This motion turns out to be possible if the magnetic field is applied along the most easy axis. The symmetry approach prohibits the directed DW motion if the magnetic field is applied along any of the hard axes. With the help of the soliton perturbation theory and numerical simulations, the average DW velocity as a function of different system parameters such as damping constant, amplitude, and frequency of the external field, is computed.Comment: Added references, corrected typos, extended introductio

Broken symmetries and directed collective energy transport

We study the appearance of directed energy current in homogeneous spatially extended systems coupled to a heat bath in the presence of an external ac field E(t). The systems are described by nonlinear field equations. By making use of a symmetry analysis we predict the right choice of E(t) and obtain directed energy transport for systems with a nonzero topological charge Q. We demonstrate that the symmetry properties of motion of topological solitons (kinks and antikinks) are equivalent to the ones for the energy current. Numerical simulations confirm the predictions of the symmetry analysis and, moreover, show that the directed energy current drastically increases as the dissipation parameter $\alpha$ reduces. Our results generalize recent rigorous theories of currents generated by broken time-space symmetries to the case of interacting many-particle systems.Comment: 4 pages, 2 figure

Rectification and Phase Locking for Particles on Two Dimensional Periodic Substrates

We show that a novel rectification phenomena is possible for overdamped particles interacting with a 2D periodic substrate and driven with a longitudinal DC drive and a circular AC drive. As a function of DC amplitude, the longitudinal velocity increases in a series of quantized steps with transverse rectification occuring near these transitions. We present a simple model that captures the quantization and rectification behaviors.Comment: 4 pages, 4 postscript figure

In-plane fluxon in layered superconductors with arbitrary number of layers

I derive an approximate analytic solution for the in-plane vortex (fluxon) in layered superconductors and stacked Josephson junctions (SJJ's) with arbitrary number of layers. The validity of the solution is verified by numerical simulation. It is shown that in SJJ's with large number of thin layers, phase/current and magnetic field of the fluxon are decoupled from each other. The variation of phase/current is confined within the Josephson penetration depth, $\lambda_J$, along the layers, while magnetic field decays at the effective London penetration depth, $\lambda_c \gg \lambda_J$. For comparison with real high-$T_c$ superconducting samples, large scale numerical simulations with up to 600 SJJ's and with in-plane length up to 4000 $\lambda_J$%, are presented. It is shown, that the most striking feature of the fluxon is a Josephson core, manifesting itself as a sharp peak in magnetic induction at the fluxon center.Comment: 4 pages, 4 figures. Was presented in part at the First Euroconference on Vortex Matter in Superconductors (Crete, September 1999

The structure of the superconducting gap in MgB2 from point-contact spectroscopy

We have studied the structure of the superconducting gap in MgB2 thin films by means of point-contact spectroscopy using a gold tip. The films were produced by depositing pure boron on a sapphire substrate, using e-beam evaporation, followed by reaction with magnesium vapour. The films have a Tc of 38.6 +- 0.3 K and resistivity of about 20 microOhm cm at 40 K. The point-contact spectra prove directly the existence of a multi-valued order parameter in MgB2, with two distinct values of the gap, DELTA1=2.3+-0.3 meV and DELTA2=6.2+-0.7 meV at 4.2 K. Analysis of the spectra in terms of the Blonder-Tinkham-Klapwijk model reveals that both gaps close simultaneously at the Tc of the film. Possible mechanisms that can explain the intrinsic co-existence of two values of the gap are discussed.Comment: 9 pages, 9 figure

Progress in the development of a KITWPA for the DARTWARS project

DARTWARS (Detector Array Readout with Traveling Wave AmplifieRS) is a three years project that aims to develop high-performing innovative Traveling Wave Parametric Amplifiers (TWPAs) for low temperature detectors and qubit readout (C-band). The practical development follows two different promising approaches, one based on the Josephson junctions (TWJPA) and the other one based on the kinetic inductance of a high-resistivity superconductor (KITWPA). This paper presents the advancements made by the DARTWARS collaboration to produce a first working prototype of a KITWPA.Comment: 3 pages, 4 figures. Proceeding of Pisa15th Meeting conferenc

The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells

open15noBackground: Glioblastoma multiforme (GBM), due to its location, aggressiveness, heterogeneity and infiltrative growth, is characterized by an exceptionally dismal clinical outcome. The small molecule SI113, recently identified as a SGK1 inhibitor, has proven to be effective in restraining GBM growth in vitro and in vivo, showing also encouraging results when employed in combination with other antineoplastic drugs or radiotherapy. Our aim was to explore the pharmacological features of SI113 in GBM cells in order to elucidate the pivotal molecular pathways affected by the drug. Such knowledge would be of invaluable help in conceiving a rational offensive toward GBM. Methods: We employed GBM cell lines, either established or primary (neurospheres), and used a Reverse-Phase Protein Arrays (RPPA) platform to assess the effect of SI113 upon 114 protein factors whose post-translational modifications are associated with activation or repression of specific signal transduction cascades.Results: SI113 strongly affected the PI3K/mTOR pathway, evoking a pro-survival autophagic response in neurospheres. These results suggested the use of SI113 coupled, for maximum efficiency, with autophagy inhibitors. Indeed, the association of SI113 with an autophagy inhibitor, the antimalarial drug quinacrine, induced a strong synergistic effect in inhibiting GBM growth properties in all the cells tested, including neurospheres. Conclusions: RPPA clearly identified the molecular pathways influenced by SI113 in GBM cells, highlighting their vulnerability when the drug was administered in association with autophagy inhibitors, providing a strong molecular rationale for testing SI113 in clinical trials in associative GBM therapy.openMatteoni S.; Abbruzzese C.; Matarrese P.; De Luca G.; Mileo A.M.; Miccadei S.; Schenone S.; Musumeci F.; Haas T.L.; Sette G.; Carapella C.M.; Amato R.; Perrotti N.; Signore M.; Paggi M.G.Matteoni, S.; Abbruzzese, C.; Matarrese, P.; De Luca, G.; Mileo, A. M.; Miccadei, S.; Schenone, S.; Musumeci, F.; Haas, T. L.; Sette, G.; Carapella, C. M.; Amato, R.; Perrotti, N.; Signore, M.; Paggi, M. G