825 research outputs found

    Towards a resilient community: A decision support framework for prioritizing stakeholders' interaction areas

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    Interactions among community stakeholders act as a buffer against disasters and present a way to build community resilience. Several decision support frameworks have been proposed in the literature to improve community resilience, but none focus on interactions among stakeholders. This paper presents a decision support framework to guide decision-makers in prioritizing areas of interaction based on their mutual impact. The framework is built on three components. The first involved conducting a literature review to identify areas of interaction among community stakeholders; resulting in identifying 27 factors that reflect the various interaction areas. The second was to implement a Delphi study to capture the dependency among the different areas. The third was to prioritize the identified areas of interaction through network analysis techniques to understand the propagating impacts of a change in one area on the others. The framework was applied to Spain, utilizing data provided by Spanish resilience experts. Our findings indicate a high degree of interdependence among all areas of interaction. Decentralization of the decision-making process and effective leading capabilities of emergency organizations have been identified as top priority areas. By utilizing this framework, decision-makers can systematically enhance interactions among diverse stakeholders, creating a roadmap to improve community resilience

    Gender Specific Disruptions in Emotion Processing in Younger Adults with Depression

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    Background: One of the principal theories regarding the biological basis of major depressive disorder (MDD) implicates a dysregulation of emotion-processing circuitry. Gender differences in how emotions are processed and relative experience with emotion processing might help to explain some of the disparities in the prevalence of MDD between women and men. This study sought to explore how gender and depression status relate to emotion processing. Methods: This study employed a 2 (MDD status) × 2 (gender) factorial design to explore differences in classifications of posed facial emotional expressions (N=151). Results: For errors, there was an interaction between gender and depression status. Women with MDD made more errors than did nondepressed women and men with MDD, particularly for fearful and sad stimuli (Ps Ps P=.01). Men with MDD, conversely, performed similarly to control men (P=.61). Conclusions: These results provide novel and intriguing evidence that depression in younger adults (years) differentially disrupts emotion processing in women as compared to men. This interaction could be driven by neurobiological and social learning mechanisms, or interactions between them, and may underlie differences in the prevalence of depression in women and men. Depression and Anxiety, 2009. Published 2008 Wiley-Liss, Inc

    Hallazgos neurorradiológicos de la Acidosis Glutárica tipo I

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    Glutaric aciduria type I is a rare disorder of organic acid metabolism caused by deficiency of glutaryl-CoA dehydrogenase, a mitochondrial enzyme. Improper degeneration of amino acids: tryptophan, lysine, and hydroxylysine, results in increased levels of glutaric acid, which typically becomes clinically manifest as an acute dystonic crisis in young children. Accumulation of glutaric acid causes neurotoxicity in the basal ganglia and fronto-temporal cortex which can lead to progressive dystonia, hypotonia, permanently impaired speech and seizures. Because dietary and drug therapy may alter the natural history of the disease, early diagnosis of such patients is critical. We report the magnetic resonance (MR) imaging findings in a 16 year-old girl with this disorder who presented with a chronic dystonic syndrome and previously diagnosed of brain paralysis. MR imaging demonstrated bilateral involvement of the putamina and periventricular white matter, and bilateral temporal atrophy and widened Silvian fissure

    Piii‐37

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109838/1/cptclpt2006257.pd

    Systematic approach to cyber resilience operationalization in SMEs

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    The constantly evolving cyber threat landscape is a latent problem for today’s companies. This is especially true for the Small and Medium-sized Enterprises (SMEs) because they have limited resources to face the threats but, as a group, represent an extensive payload for cybercriminals to exploit. Moreover, the traditional cybersecurity approach of protecting against known threats cannot withstand the rapidly evolving technologies and threats used by cybercriminals. This study claims that cyber resilience, a more holistic approach to cybersecurity, could help SMEs anticipate, detect, withstand, recover from and evolve after cyber incidents. However, to operationalize cyber resilience is not an easy task, and thus, the study presents a framework with a corresponding implementation order for SMEs that could help them implement cyber resilience practices. The framework is the result of using a variation of Design Science Research in which Grounded Theory was used to induce the most important actions required to implement cyber resilience and an iterative evaluation from experts to validate the actions and put them in a logical order. Therefore, this study proposes that the framework could benefit SME managers to understand cyber resilience, as well as help them start implementing it with concrete actions and an order dictated by the experience of experts. This could potentially ease cyber resilience implementation for SMEs by making them aware of what cyber resilience implies, which dimensions it includes and what actions can be implemented to increase their cyber resilience

    The double burden of age and disease on cognition and quality of life in bipolar disorder

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108337/1/gps4084.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/108337/2/gps4084-sup-0002-TableS1.pd

    Functional bold MRI: advantages of the 3 T vs. the 1.5 T

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    We quantitatively evaluate the benefits of a higher field strength for functional brain MRI (fMRI) based on the blood oxygenation level-dependent contrast. The 3-T fMRI shows a higher sensitivity for the motor and somatosensory stimulation and more specific localization in the grey substance. The 3-T fMRI detects additional areas of activation with the motor paradigm
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