753 research outputs found

    Angiogenesis and Vasculogenesis at 7-Day of Reperfused Acute Myocardial Infarction

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    Objectives 
This study is to investigate the angiogenesis and vasculogenesis at the first week of reperfused acute myocardial infarction (AMI).
Methods 
16 of mini-swines (20 to 30 Kg) were randomly assigned to the sham-operated group and the AMI group. The acute myocardial infarction and reperfusion model was created and the pig tail catheter was performed to monitor hemodynamics before left anterior descending coronary artery (LAD) occlusion, 90 min of LAD occlusion and 120 min of LAD reperfusion. Pathologic myocardial tissue was collected at 7-day of LAD reperfusion and further assessed by immunochemistry, dual immunochemistry, in-situ hybridization, real-time quantitative polymerase chain reaction and western blot. 
Results 
The infarcted area had higher FLK1 mRNA expression than sham-operated area and the normal area (all P<0.05), and the infarcted and marginal areas showed higher CD146 protein expression than the sham-operated area (all P<0.05), but the microvessel density (CD31 positive expression of microvessels/HP) was not significantly different between the infarcted area and the sham-operated area (8.92±3.05 vs 6.43±1.54) at 7-day of reperfused acute myocardial infarction (P>0.05). 
Conclusions 
FLK1 and CD146 expression significantly increase in the infarcted and marginal areas, and the microvessel density is not significantly different between the infarcted area and the sham-operated area, suggesting that angiogenesis and vasculogenesis in the infarcted area appear to high frequency of increase in 7-day of reperfused myocardial infarction. 
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    AdS/QCD Phenomenological Models from a Back-Reacted Geometry

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    We construct a fully back-reacted holographic dual of a four-dimensional field theory which exhibits chiral symmetry breaking. Two possible models are considered by studying the effects of a five-dimensional field, dual to the qqˉq\bar{q} operator. One model has smooth geometry at all radii and the other dynamically generates a cutoff at finite radius. Both of these models satisfy Einstein's field equations. The second model has only three free parameters, as in QCD, and we show that this gives phenomenologically consistent results. We also discuss the possibility that in order to obtain linear confinement from a back-reacted model it may be necessary to consider the condensate of a dimension two operator.Comment: 13 pages, 4 figures, Replaced with minor correction

    Quantum oscillations of robust topological surface states up to 50 K in thick bulk-insulating topological insulator

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    As personal electronic devices increasingly rely on cloud computing for energy-intensive calculations, the power consumption associated with the information revolution is rapidly becoming an important environmental issue. Several approaches have been proposed to construct electronic devices with low-energy consumption. Among these, the low-dissipation surface states of topological insulators (TIs) are widely employed. To develop TI-based devices, a key factor is the maximum temperature at which the Dirac surface states dominate the transport behavior. Here, we employ Shubnikov-de Haas oscillations (SdH) as a means to study the surface state survival temperature in a high-quality vanadium doped Bi1.08Sn0.02Sb0.9Te2S single crystal system. The temperature and angle dependence of the SdH show that: (1) crystals with different vanadium (V) doping levels are insulating in the 3-300 K region; (2) the SdH oscillations show two-dimensional behavior, indicating that the oscillations arise from the pure surface states; and (3) at 50 K, the V0.04 single crystals (Vx:Bi1.08-xSn0.02Sb0.9Te2S, where x = 0.04) still show clear sign of SdH oscillations, which demonstrate that the surface dominant transport behavior can survive above 50 K. The robust surface states in our V doped single crystal systems provide an ideal platform to study the Dirac fermions and their interaction with other materials above 50 K

    Enhanced Light Utilization in Semitransparent Organic Photovoltaics Using an Optical Outcoupling Architecture

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    Buildingâ integrated photovoltaics employing transparent photovoltaic cells on window panes provide an opportunity to convert solar energy to electricity rather than generating waste heat. Semitransparent organic photovoltaic cells (STâ OPVs) that utilize a nonfullerene acceptorâ based nearâ infrared (NIR) absorbing ternary cell combined with a thin, semitransparent, high conductivity Cuâ Ag alloy electrode are demonstrated. A combination of optical outcoupling and antireflection coatings leads to enhanced visible transmission, while reflecting the NIR back into the cell where it is absorbed. This combination of coatings results in doubling of the light utilization efficiency (LUE), which is equal to the product of the power conversion efficiency (PCE) and the average photopic transparency, compared with a conventional semitransparent cell lacking these coatings. A maximum LUE = 3.56 ± 0.11% is achieved for an STâ OPV with a PCE = 8.0 ± 0.2% at 1 sun, reference AM1.5G spectrum. Moreover, neutral colored STâ OPVs are also demonstrated, with LUE = 2.56 ± 0.2%, along with Commission Internationale d’Eclairage chromaticity coordinates of CIE = (0.337, 0.349) and a color rendering index of CRI = 87.An efficient and neutral colored semitransparent organic photovoltaic cell (STâ OPV) is realized by utilizing a nearâ infrared (NIR) absorbing ternary cell combined with a thin, semitransparent, highâ conductivity Cuâ Ag alloy electrode. A combination of optical outcoupling and antireflection coatings leads to enhanced visible transmission, while reflecting the NIR back into the cell where it is absorbed.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151812/1/adma201903173.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151812/2/adma201903173_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151812/3/adma201903173-sup-0001-S1.pd

    A general model for collaboration networks

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    In this paper, we propose a general model for collaboration networks. Depending on a single free parameter "{\bf preferential exponent}", this model interpolates between networks with a scale-free and an exponential degree distribution. The degree distribution in the present networks can be roughly classified into four patterns, all of which are observed in empirical data. And this model exhibits small-world effect, which means the corresponding networks are of very short average distance and highly large clustering coefficient. More interesting, we find a peak distribution of act-size from empirical data which has not been emphasized before of some collaboration networks. Our model can produce the peak act-size distribution naturally that agrees with the empirical data well.Comment: 10 pages, 10 figure

    Genomic diversity among Basmati rice (Oryza sativa L) mutants obtained through 60Co gamma radiations using AFLP markers

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    Mutation breeding can be considered successful in obtaining new cultivars and broadening the genetic base of rice crop. In order to obtain new varieties of rice with improved agronomic and grain characteristics, gamma radiation (60Co) has been used to generate novel mutants of the Basmati rice. In this study rice cultivars; Basmati-370 and Basmati-Pak, were exposed to different doses of gamma radiations and stable mutants along with parents were studied for genomic diversity on the basis of molecular marker (AFLP). Morphological data showed that mutants of Basmati-370 performed well for yield and yield components and grain physical parameters whereas, the mutant EL-30-2-1 has extra long rain trait as compared to the parent (Basmati-Pak). The genetic variations determined through AFLP revealed a total of 282 scorable bands, out of which 108 (37.81%) were polymorphic. The number of fragments produced by various primers combinations ranged from 11 - 26 with an average of 17.63fragments per primer combination. Maximum 26 bands were amplified with P-AAG/M-CAG primer combination and minimum one band was amplified with P-ATG/M-CTA primer combination. Two groups of genotypes were detected; group-A had DM-1-30-3-99, DM-1-30-34-99 and EF-1-20-52-04 mutants along with parent Basmati-370, whereas the group-B contained EL-30-2-1 and parent Basmati-Pak. The results of AFLP analysis indicated that the rate of polymorphism was 4.43% (DM-1-30-3-99), 4.25% (DM-1-30-34-99) and 6.38% (EF-1-20-52-04) among the genomes of mutants and parent Basmati-370, respectively, whereas polymorphism rate was 5.32% between genome of EL-30-2-1 and Basmati-Pak. The study further confirmed that the use of gamma radiations is an effective approach for creating new rice germplasm

    Pair production of the T-odd leptons at the LHC

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    The T-odd leptons predicted by the littlest HiggsHiggs model with T-parity can be pair produced via the subprocesses ggH+Hgg\to \ell^{+}_{H}\ell^{-}_{H}, qqˉH+Hq\bar{q}\to \ell^{+}_{H}\ell^{-}_{H}, γγH+H\gamma\gamma\to \ell^{+}_{H}\ell^{-}_{H} and VVH+H VV \to \ell^{+}_{H}\ell^{-}_{H} (VV=WW or ZZ) at the CERNCERN Large Hadron Collider (LHC)(LHC). We estimate the hadronic production cross sections for all of these processes and give a simply phenomenology analysis. We find that the cross sections for most of the above processes are very small. However, the value of the cross section for the DrellYanDrell-Yan process qqˉH+Hq\bar{q}\to \ell^{+}_{H}\ell^{-}_{H} can reach 270fb270fb.Comment: 12 pages, 2 figure
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