Lymphoma caused by intestinal microbiota.

The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions of microbes in and on our body are innocuous symbionts and some can even be beneficial. Since there is such a close interaction between the immune system and the intestinal microbiota, it is not surprising that some lymphomas such as mucosal-associated lymphoid tissue (MALT) lymphoma have been shown to be caused by the presence of certain bacteria. Animal models played an important role in establishing causation and mechanism of bacteria-induced MALT lymphoma. In this review we discuss different ways that animal models have been applied to establish a link between the gut microbiota and lymphoma and how animal models have helped to elucidate mechanisms of microbiota-induced lymphoma. While there are not a plethora of studies demonstrating a connection between microbiota and lymphoma development, we believe that animal models are a system which can be exploited in the future to enhance our understanding of causation and improve prognosis and treatment of lymphoma

Lipschitz stability for an inverse hyperbolic problem of determining two coefficients by a finite number of observations

We consider an inverse problem of reconstructing two spatially varying coefficients in an acoustic equation of hyperbolic type using interior data of solutions with suitable choices of initial condition. Using a Carleman estimate, we prove Lipschitz stability estimates which ensures unique reconstruction of both coefficients. Our theoretical results are justified by numerical studies on the reconstruction of two unknown coefficients using noisy backscattered data

Direct numerical simulation of dispersed particles in a compressible fluid

We present a direct numerical simulation method for investigating the dynamics of dispersed particles in a compressible solvent fluid. The validity of the simulation is examined by calculating the velocity relaxation of an impulsively forced spherical particle with a known analytical solution. The simulation also gives information about the fluid motion, which provides some insight into the particle motion. Fluctuations are also introduced by random stress, and the validity of this case is examined by comparing the calculation results with the fluctuation-dissipation theorem.Comment: 7 pages, 5 figure

Mott transitions of exciton-polaritons and indirect excitons in a periodic potential

We derive an effective Bose-Hubbard model that predicts a phase transition from Bose-Einstein condensate to Mott insulator in two different systems subject to applied periodic potentials: microcavity exciton-polaritons and indirect excitons. Starting from a microscopic Hamiltonian of electrons and holes, we derive an effective Bose-Hubbard model for both systems and evaluate the on-site Coulomb interaction U and hopping transition amplitudes t. Experimental parameters required for observing a phase transition between a Bose-Einstein condensate and a Mott insulator are discussed. Our results suggest that strong periodic potentials and polaritons with a very large excitonic component are required for observing the phase transition. The form of the indirect exciton interaction is derived including direct and exchange components of the Coulomb interaction. For indirect excitons, the system crosses over from a Bose-Hubbard model into a double layer Fermi-Hubbard model as a function of increasing bilayer separation. The Fermi-Hubbard model parameters are calculated, and the criteria for the location of this crossover are derived. We conjecture that a crossover between a Bose Mott insulator to a Fermi Mott insulator should occur with increasing bilayer separation.Comment: 30 pages, 8 figure

Critical velocity of flowing supersolids of dipolar Bose gases in optical lattices

We study superfluidity of supersolid phases of dipolar Bose gases in two-dimensional optical lattices. We perform linear stability analyses for the corresponding dipolar Bose-Hubbard model in the hardcore boson limit to show that a supersolid can have stable superflow until the flow velocity reaches a certain critical value. The critical velocity for the supersolid is found to be significantly smaller than that for a conventional superfluid phase. We propose that the critical velocity can be used as a signature to identify the superfluidity of the supersolid phase in experiment.Comment: 7 pages, 4 figures, published versio

Electronic Transport in Fullerene C20 Bridge Assisted by Molecular Vibrations

The effect of molecular vibrations on electronic transport is investigated with the smallest fullerene C20 bridge, utilizing the Keldysh nonequilibrium Green's function techniques combined with the tight-binding molecular-dynamics method. Large discontinuous steps appear in the differential conductance when the applied bias-voltage matches particular vibrational energies. The magnitude of the step is found to vary considerably with the vibrational mode and to depend on the local electronic states besides the strength of electron-vibration coupling. On the basis of this finding, a novel way to control the molecular motion by adjusting the gate voltage is proposed.Comment: 9 pages, 4 figures, accepted for publication in Phys. Rev. Let