Scenario-based sustainable water management and urban regeneration

Copyright © ICE PublishingDeployable output (source availability) from water resources in north west England is predicted to decrease over the next 25 years. Alternative supply management strategies are planned to help avoid a deficit in the supply–demand balance within the region but have yet to be considered in detail. This paper assesses the contribution of such an alternative supply strategy at local level on the water resource supply–demand balance at regional level based on a proposed urban regeneration site in north west England. Various water conservation and reuse measures are investigated considering local and regional conditions and constraints. Four future scenarios are presented and used to describe how the future might be (rather than how it will be), to allow an assessment to be made of how current ‘sustainable solutions’ might cope whatever the future holds. The analysis determines the solution contributions under each future and indicates that some strategies will deliver their full intended benefits under scenarios least expected but most needed. It is recommended that to help reduce the regional supply–demand deficit and maximise system resilience to future change, a wide range of water demand management measures should be incorporated on this and other sites

Transitional Justice in a Transnational World: The Ambiguous Role of Law

In situations of military, political or economic transition, the reassessment of the role of law in the transition process becomes a crucial site of a people\u27s or a nation\u27s negotiating the past, present and future. Allusions to a tabula rasa or an annee zero after traumatic collapses of societal order, however, turn into ill-fated attempts to address the challenges of confronting the past when building the future. The law\u27s concern with nations that struggle with transition expresses itself through hybrid concepts such as transitional or post-conflict justice, restorative justice, or reconciliation. This paper revisits these instantiations and places them in the context of an increasingly transnational discourse on transitional justice. In light of the wealth of law and non-law responses to past injustice around the world today, transitional justice emerges as a form of transnational legal pluralism, highlighting the parallels of regulatory challenges confronting transition and established regimes alike

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Exploring the potential impact of Project 2000 on local staff nurse development A collaborative research project

SIGLEAvailable from British Library Document Supply Centre- DSC:q93/08885(Exploring) / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Functional variation of MC1R alleles from red-haired individuals

Red hair in humans is associated with variant alleles of the MSH receptor gene, MC1R. Loss of MC1R function in other mammals results in red or yellow hair pigmentation. We show that a mouse bacterial artificial chromosome (BAC) which contains Mc1r will efficiently rescue loss of Mc1r in transgenic mice, and that overexpression of the receptor suppresses the effect of the endogenous antagonist, agouti protein. We engineered the BAC to replace the mouse coding region with the human MC1R sequence and used this in the transgenic assay. The human receptor also efficiently rescued Mc1r deficiency, and in addition, appeared to be completely resistant to the effects of agouti, suggesting agouti protein may not play a role in human pigmentary variation. Three human variant alleles account for 60% of all cases of red hair. We engineered each of these in turn into the BAC and find that they have reduced, but not completely absent, function in transgenic mice. Comparison of the phenotypes of MSH-deficient mice and humans in conjunction with this data suggests that red hair may not be the null phenotype of MC1R

A Study of the Molecular and Electronic Structure of Iron (II) and Ruthenium (II) 1,3-Di and 1,2,4-Triphospholyl sandwich compounds by Photoelectron Spectroscopy and Density Functional Theory

The synthesis and variable temperature 1H NMR spectrum of the new tetraphosphaferrocene [Fe(η5-P2C3Bu3t)2] are presented and the photoelectron spectra are reported for [Fe(η5-P3C2Bu2t)2] 1a, [Fe(η5-P2C3Bu3t)2] 2a, [Fe(η5-P2C3Bu3t)(η5-P3C2Bu2t)] 3a and [Ru(η5-P3C2Bu3t)2] 4a. Density functional calculations were used to optimise the geometry and calculate the ionization energies of the parent analogues. Good agreement was obtained with the experimental results, giving support to the theoretical modelling of these sandwich compounds. Analysis of their electronic structure showed that replacement of RC fragments by P atoms in the η5-ligated cyclopentadienyl rings increases their acceptor properties. Extensive σπ mixing makes the description of the orbitals complex. Some higher lying Pσ levels are found to have similar ionization energies to the d electrons

Base flow of 10 south-shore streams, Long Island, New York, 1976-85, and the effects of urbanization on base flow and flow duration /

Shipping list no.: 92-0595-P.Includes bibliographical references (p. 33-34).Mode of access: Internet