1,488 research outputs found
Occupational Therapy’s Role in Early Language Development of Babies and Young Children
Occupational therapy practitioners in their interactions with babies, young children and their families, can be change-agents who promote rich language environments as a foundation to social interactions, social participation and academic successes. OTPs may be the sole provider working with a family or may reinforce with families the plan of care developed by speech-language pathologists (SLP) or early intervention teachers. The first step for OTPs is deeper knowledge of the importance of early language exposure, social interaction and participation development in young children and approaches that promotes rich language environments
A Company-Wide Initiative to Improve Screening for Vision Impairment
Objectives: \u3e 1 out of 6 point up in knowledge of vision impairment & confidence in screening (6 questions; 1=strongly disagree to 7=strongly agree) 40% of clients will undergo vision screening Identify & resolve barriers to vision screening (4 questions
Sensory-Based Interventions in the School Setting: Perspectives of Paraeducators
Sensory experiences or environmental modifications can: Regulate behavior Improve sensory modulation Improve readiness for activities Improve focus for learnin
A Systematic Review of the Efficacy of Motivational Interviewing on Occupational Performance
This systematic review aims to review the efficacy of MI to address such performance goals falling within the occupational therapy scope of practice
Efficacy of alternative seating on attention, in-seat behavior, and occupational performance in children with Attention Deficit Hyperactivity Disorder
Currently, there is one systematic review conducted by Gochenour and Poskey7 that synthesize current research evidence regarding alternative seating for students with attention difficulties. A limitation of this review, as noted by the authors, is a lack of a consistent definition of attention difficulty in the studies they included. A systematic review focused on a specific, well-defined diagnosis will better contribute to practice recommendations since these recommendations will be tailored to a clear and comprehensive understanding of the child’s attentional and occupational challenges. The review also included studies of children with autism spectrum disorder (ASD).7 While those with ASD may also have difficulties with attention, in-seat behavior and occupational performance, the underlying mechanism yielding these symptoms may be different than in children with ADHD. Thus, alternative seating may not work in the same way for children with ASD as it would for children with ADHD.7 Thus, a systematic review is needed to examine the evidence from all current studies regarding alternative seating on improving attention, in-seat behavior and occupational performance in students with ADHD to increase evidence-based practice in the field of occupational therapy
A Systematic Review: Light Therapy for Individuals with Dementia and Implications for Practice
This systematic review seeks to answer the question: is light therapy an effective intervention for sundowning symptoms experienced by individuals who have dementia
Scattering of Glueballs and Mesons in Compact in Dimensions
We study glueball and meson scattering in compact gauge theory in
a Hamiltonian formulation and on a momentum lattice. We compute ground state
energy and mass, and introduce a compact lattice momentum operator for the
computation of dispersion relations. Using a non-perturbative time-dependent
method we compute scattering cross sections for glueballs and mesons. We
compare our results with strong coupling perturbation theory.Comment: figures not included (hard copy only), LAVAL-PHY-94-05,
PARKS-PHY-94-0
TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain
Background:
The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system. Recent data indicate that peripheral immune stimulation can significantly affect the CNS. But the mechanisms underpinning this relationship remain unclear. The standard approach to understanding this relationship has relied on systemic immune activation using bacterial components, finding that immune mediators, such as cytokines, can have a significant effect on brain function and behaviour. More rarely have studies used disease models that are representative of human disorders.
Methods:
Here we use a well-characterised animal model of psoriasis-like skin inflammation—imiquimod—to investigate the effects of tissue-specific peripheral inflammation on the brain. We used full genome array, flow cytometry analysis of immune cell infiltration, doublecortin staining for neural precursor cells and a behavioural read-out exploiting natural burrowing behaviour.
Results:
We found that a number of genes are upregulated in the brain following treatment, amongst which is a subset of inflammatory chemokines (CCL3, CCL5, CCL9, CXCL10, CXCL13, CXCL16 and CCR5). Strikingly, this model induced the infiltration of a number of immune cell subsets into the brain parenchyma, including T cells, NK cells and myeloid cells, along with a reduction in neurogenesis and a suppression of burrowing activity.
Conclusions:
These findings demonstrate that cutaneous, peripheral immune stimulation is associated with significant leukocyte infiltration into the brain and suggest that chemokines may be amongst the key mediators driving this response
The quantum structure of black holes
We give an elementary review of black holes in string theory. We discuss
black hole entropy from string microstates and Hawking radiation from these
states. We then review the structure of 2-charge microstates, and explore how
`fractionation' can lead to quantum effects over macroscopic length scales of
order the horizon radius.Comment: Review article, 58 pages, 2 figures; references added, note about
topics covere
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