The superconducting proposal for the CS magnet system of FAST: a preliminary analysis of the heat load due to AC losses

FAST (Fusion Advanced Studies Torus), the Italian proposal of a Satellite Facility to ITER, is a compact tokamak (R$_0$ = 1.82 m, a = 0.64 m, triangularity $\delta$ = 0.4) able to investigate non-linear dynamics effects of $\alpha$-particle behavior in burning plasmas and to test technical solutions for the first wall/divertor directly relevant for ITER and DEMO. Currently, ENEA is investigating the feasibility of a superconducting solution for the magnet system. This paper focuses on the analysis of the CS (Central Solenoid) magnet thermal behavior. In particular, considering a superconducting solution for the CS which uses the room available in the resistive design and referring to one of the most severe scenario envisaged for FAST, the heat load of the CS winding pack due to AC losses is preliminarily evaluated. The results provide a tentative baseline for the definition of the strand requirements and conductor design, that can be accepted in order to fulfil the design requirements.Comment: 15 pages, 5 figure

Robustness of the 0−π0 -\pi transition against compositional and structural ageing in S/F/S heterostructures

We have studied the temperature induced $0 -\pi$ thermodynamic transition in Nb/PdNi/Nb Superconductor/Ferromagnetic/Superconductor (SFS) heterostructures by microwave measurements of the superfluid density. We have observed a shift in the transition temperature with the ageing of the heterostructures, suggesting that structural and/or chemical changes took place. Motivated by the electrodynamics findings, we have extensively studied the local structural properties of the samples by means of X-ray Absorption Spectroscopy (XAS) technique, and the compositional profile by Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS). We found that the samples have indeed changed their properties, in particular for what concerns the interfaces and the composition of the ferromagnetic alloy layer. The structural and compositional data are consistent with the shift of the $0-\pi$ transition toward the behaviour of heterostructures with different F layers. An important emerging indication to the physics of SFS is the weak relevance of the ideality of the interfaces: even in aged samples, with less-than-ideal interfaces, the temperature-induced $0-\pi$ transition is still detectable albeit at a different critical F thickness.Comment: 11 pages, 9 figures, accepted for publication on Phys. Rev. B, http://journals.aps.org/prb

Surface water interaction with the flood plain in the lower Virgin River, Clark County, Nevada

Development of existing surface water rights on the Virgin River would decrease Southern Nevada\u27s dependency on the Colorado River. Three monitoring sites were established to examine the relationship between Virgin River surface water flows and the floodplain aquifer. Automated water level measuring devices were installed in piezometers and wells to continuously track water levels and flow direction. Pump tests were conducted to establish the hydraulic parameters of the floodplain aquifer. Water chemistry data was analyzed to help determine the correlation between the floodplain aquifer and Virgin River water. Precipitation, recharge, streamflow and ET estimates were used to discuss water budgets. Results from this study will increase knowledge of surface water interaction with the floodplain aquifer in the lower Virgin River and provide additional information to assist on-going analyses associated with proposed surface water development projects in the lower Virgin River

Effects of lung volume reduction surgery for emphysema on glycolipidic hormones

BACKGROUND: Pulmonary emphysema is associated with cachexia and disregulation of the hormones regulating the glycolipid metabolism, insulin resistance, and altered substrate utilization. This study aimed at identifying the effects of lung volume reduction surgery (LVRS) on glycolipidic hormones compared to respiratory rehabilitation (RR). METHODS: Thirty-three patients with moderate-to-severe emphysema who were undergoing video-assisted thoracoscopic LVRS were compared to 31 similar patients who refused the operation and followed a standardized RR program. All patients were evaluated before and 12 months after treatment for respiratory function, body composition, glycolipidic hormones, metabolic parameters, and insulin resistance, which was calculated using the homeostatic model assessment index for insulin resistance (HOMA-IR). These groups were compared to a matched healthy control population. RESULTS: Only after LVRS significant improvements were obtained in respiratory function (FEV1, +25.2%; p<0.0001; residual volume, -19.5%; p<0.0001), metabolic parameters (total cholesterol, +13.1%; p<0.01; high-density lipoprotein cholesterol, +11.2%; p<0.01; triglycerides, +18.4; p<0.001; nonesterified fatty acid, -19.7%; p<0.001), and body composition (fat-free mass [FFM], +6.5%; p<0.01; fat mass [FM], +11.9%; p<0.01). The leptin/FM ratio (-6.1%; p<0.01) and resistin/FM ratio (-5.6%; p<0.01) decreased, whereas the adiponectin/FM ratio (+6.9%; p<0.01) and ghrelin (+9.2%; p<0.01) increased, together with reductions in glycemia (-8.8%; p<0.01), insulin level (-20.4%; p<0.001), and HOMA-IR (-27.2%; p<0.0001). The decrement in residual volume was correlated with increment of FFM (rho=-0.49; p<0.02), FM (rho=-0.55; p<0.009), and ghrelin (rho=-0.52; p<0.01), and also with decreases in leptin corrected for FM (rho=0.50; p<0.02) and, marginally, HOMA-IR (rho=0.35; p=0.07). CONCLUSIONS: After LVRS, glycolipidic hormone levels and nutritional status significantly improved, along with insulin resistance reduction and more physiologic utilization of substrates. Correlations between residual volume and body composition as well as glycolipidic hormone levels suggest that postoperative recovery in respiratory dynamics may induce favorable clinical changes when compared to RR

Manutenção em campo de níveis variados de palhada de cana-de-açúcar: efeitos sobre o acúmulo de nitrogênio nas plantas.

Resumo: O objetivo do trabalho foi estudar a contribuição de diferentes níveis de palhada sobre o acumulo de nitrogênio na cana-de-açúcar. O ensaio foi instalado em Araras-SP, durante as safras de 2011-12 e 2012-13 (variedade RB-845210). Foram aplicados cinco tratamentos, com níveis de 0%, 25%, 50%, 75% e 100% (0 - 2,8- 5,7- 8,5 -11,3 t ha-1 safra 2011-12) (0 - 3 - 6,2 - 9,4 - 12,8 t ha-1 safra 2012-13) dispostos em blocos ao acaso com quatro repetições. Para acompanhar o acumulo de N nos diferentes compartimentos da planta (folhas verdes, folhas secas e colmo) de cana-de-açúcar foram utilizados os dados de massa seca (kg ha-1) e concentrações de N (g kg-1) de cada um destes componentes, obtidos em biometrias realizadas ao longo dos dois ciclos de cultivos estudados. Utilizou-se a análise de variância e regressão para o tratamento estatístico dos resultados. Foi possível concluir que: a manutenção de quantidades de palhada entre 5-12 t ha-1 promovem o mesmo acúmulo de nitrogênio no colmo em relação à ausência deste resíduo (sem palhada) somente após dois ciclos de cultivo de cana-de-açúcar; sendo que no primeiro ciclo há superioridade do tratamento sem palhada apenas sobre o maior nível deste resíduo; não há uma tendência consistente para o acúmulo de nitrogênio para as folhas verdes e secas em função de diferentes aportes de palhada sobre o solo. Abstract: The aim of this study was to evaluate the contribution of different levels of straw on the accumulation of nitrogen in sugarcane. The trial was conducted at the harvests of 2011-12 and 2012-13 in Araras-SP, using the RB-845210 variety. There were tested five levels of straw (0% - 25% - 50% - 75% - 100%), related with 2,8 - 5,7 - 8,5 -11,3 t ha -1 ( 2011-12) and 3,0 ? 6,2 ? 9,4 ? 12,8 t ha -1 (2012-13), that were arranged in a randomized block design with four replications. To determine N accumulation in sugarcane there was used dry mass (kg ha -1 ) and N concentrations (g kg -1 ) of stalk, green and dry leaves, obtained by biometry evaluations realized during the two ratoons. Variance analyses and regressions were used as statistic tool. It is possible to conclude that after two cycles of sugarcane the inputs of 5-12 t ha -1 of straw by harvest has the same contribution for nitrogen stalk accumulation than traits without straw; although in the first cycle the trait without straw is superior than the higher level of this residue. About green and dry leaves there is no tendency for the nitrogen accumulation for the input of different levels of straw in soil

Ciclagem de nutrientes em cultivo de terceira soca de cana-de-açúcar.

Resumo: O objetivo do trabalho foi avaliar a liberação de macronutrientes em função de níveis de palhada mantida sobre o solo, na terceira soca de cana-de-açúcar, e sua contribuição para ciclos posteriores. O ensaio foi instalado em Araras ?SP, safra 2011-2012 (variedade RB-845210). Os tratamentos foram os níveis de palhada 25% - 50% - 75% - 100% (2,8 - 5,7 - 8,5 -11,3 t ha-1 em base seca) dispostos em blocos ao acaso, 4 repetições. Foi utilizado o método dos ?litter bags? para avaliar a decomposição da biomassa e sua respectiva ciclagem de nutrientes. Determinou-se as concentrações (g kg-1) de N, P, K, Ca, Mg e S e as quantidades (kg ha-1) liberadas após um ciclo de cultivo. Utilizou-se a análise de variância e regressão. As concentrações de N, P, Ca e S diferiram com níveis de palhada; já o K e Mg não responderam aos tratamentos. O modelo linear melhor se ajustou para as concentrações do N, P, K e Ca, com exceção do Mg e S. Houve maior liberação de nutrientes nos maiores níveis de palhada, porém esta diferença foi atribuída ao aumento da massa entre os tratamentos. Os elementos Ca, K e N, respectivamente, foram os mais liberados, independente dos tratamentos. Conclui-se que variações na quantidade de palhada deixadas sobre o solo apresentam comportamentos diferentes de mineralização de nutrientes durante um ciclo de cultivo da cana-de-açúcar. Há maior liberação de nutrientes nos maiores níveis de palhada, sendo os elementos Ca, K e N, respectivamente, os mais liberados

Crioablação percutânea da próstata no tratamento do câncer de próstata de alto risco

PURPOSE: To evaluate percutaneous cryotherapy as a primary treatment option for high-risk prostate cancer patients. PATIENTS AND METHODS: From October 2000 to February 2005, 21 high-risk (Gleason e8 and/or PSA >; 10 and/or stage >; T2a) prostate cancer patients underwent 24 percutaneous prostate cryoablation procedures. Patients' median age was 70.9, and the average pretreatment PSA was 19.5 ng/dL. The follow-up period ranged from 6 to 60 months (median, 41 months). RESULTS: The PSA failure rate was 39%, 52.9%, and 42.8% at 12, 24, and 60 months of follow-up, respectively. Overall complication rates were low, with 8% of urinary incontinence and no cases of rectal injury; however, 96% of erectile dysfunction occurred. The cryoablation procedure failed in 12 patients (57.2%); 7 (58.3%) of these were local failures (positive prostate biopsies). CONCLUSION: Percutaneous cryoablation of the prostate is a safe minimally invasive treatment, but it has poor PSA-free survival outcomes in high-risk prostate cancer patients.OBJETIVO: Avaliar a crioterapia percutânea como tratamento primário para o câncer de próstata de alto risco. PACIENTES E MÉTODOS: De outubro de 2000 a fevereiro de 2005, 21 pacientes com câncer de próstata de alto risco foram submetidos a 24 crioablações de próstata como tratamento primário. A mediana de idade dos pacientes foi de 70,9, e a média do PSA pré-tratamento de 19,5 ng/dl. O tempo de seguimento variou de 6 a 60 meses (mediana de 41 meses). RESULTADOS: Os índices de falha do PSA foram de 39% e 52,9% respectivamente aos 12 e 24 meses de seguimento. A sobrevida livre de doença em 5 anos foi de 42,8%. De maneira geral os índices de complicações foram baixos, com 8% de incontinência urinária e nenhum caso de lesão retal. Os índices de impotência foram de 96%. Em doze pacientes (57,2%) onde houve falha da crioablação, 7 (58,3%) apresentaram recidivas locais (biópsia positiva) e os demais recidiva a distância. CONCLUSÃO: A crioablação percutânea da próstata é um tratamento minimamente invasivo da próstata, seguro, porém ainda com resultados modestos em pacientes com câncer de próstata de alto risco, quando se considera a sobrevida livre de doença em 5 anos, havendo portanto necessidade de associação de outras modalidades terapêuticas no tratamento deste grupo específico de doentes

Early and long-term results of pectoralis muscle flap reconstruction versus sternal rewiring following failed sternal closure

Objectives: The aim of the study was to compare early and long-term results of pectoralis muscle flap reconstruction with those of sternal rewiring following failed sternal closure. Primary outcomes of the study were survival and failure rate. Respiratory function, chronic pain and quality of life were also evaluated. Methods: In a propensity-score matching analysis, of 94 patients who underwent sternal reconstruction, 40 were selected; 20 underwent sternal reconstruction with bilateral pectoralis muscle flaps (Group 1) and 20 underwent sternal rewiring (Group 2). Survival and failure rates were evaluated by in-hospital records and at follow-up. Respiratory function measures, including vital capacity (VC), were evaluated both by spirometry and computed tomography (CT) volumetry. Chronic pain was evaluated by the visual analogue pain scale. Results: At 85 ± 24 months of follow-up, survival and procedure failure were 95 and 90% in Group 1 and 60 and 55% in Group 2, respectively (P < 0.01, for both comparisons). Based on CT-scan volumetry, in Group 1, severe non-union and hemisternal paradoxical movement occurred less frequently (2 vs 7, P = 0.01). At spirometry assessment, postoperative VC was greater in Group 1 (3220 ± 290 vs 3070 ± 290 ml, P = 0.04). The same trend was detected by CT-scan in-expiratory measures (4034 ± 1800 vs 3182 ± 862 mm3, P < 0.05). Correspondingly, in Group 1, less patients presented in NYHA Class III (P < 0.05), and both chronic persistent pain score and physical health quality-of-life score were significantly better in the same group. Conclusions: In our study, muscle flap reconstruction guaranteed better early and late-term results as shown by lower rates of mortality, procedure failure and hemisternum stability. Moreover, Group 1 patients had greater postoperative VC, lower NYHA class and better quality of life. These results suggest that, in patients with multiple bone fracture, the rewiring approach does not promote physiological bone consolidation, whereas the muscle flap reconstruction can assure more physiological ventilatory dynamics.© The Author 2013. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved

Early and long-term results of pectoralis muscle flap reconstruction vs sternal rewiring following failed sternal closure.

OBJECTIVES: The aim of the study was to compare early and long-term results of pectoralis muscle flap reconstruction with those of sternal rewiring following failed sternal closure. Primary outcomes of the study were survival and failure rate. Respiratory function, chronic pain and quality of life were also evaluated. METHODS: In a propensity-score matching analysis, of 94 patients who underwent sternal reconstruction, 40 were selected; 20 underwent sternal reconstruction with bilateral pectoralis muscle flaps (Group 1) and 20 underwent sternal rewiring (Group 2). Survival and failure rates were evaluated by in-hospital records and at follow-up. Respiratory function measures, including vital capacity (VC), were evaluated both by spirometry and computed tomography (CT) volumetry. Chronic pain was evaluated by the visual analogue pain scale. RESULTS: At 85 ± 24 months of follow-up, survival and procedure failure were 95 and 90% in Group 1 and 60 and 55% in Group 2, respectively (P < 0.01, for both comparisons). Based on CT-scan volumetry, in Group 1, severe non-union and hemisternal paradoxical movement occurred less frequently (2 vs 7, P = 0.01). At spirometry assessment, postoperative VC was greater in Group 1 (3220 ± 290 vs 3070 ± 290 ml, P = 0.04). The same trend was detected by CT-scan in-expiratory measures (4034 ± 1800 vs 3182 ± 862 mm3, P < 0.05). Correspondingly, in Group 1, less patients presented in NYHA Class III (P < 0.05), and both chronic persistent pain score and physical health quality-of-life score were significantly better in the same group. CONCLUSIONS: In our study, muscle flap reconstruction guaranteed better early and late-term results as shown by lower rates of mortality, procedure failure and hemisternum stability. Moreover, Group 1 patients had greater postoperative VC, lower NYHA class and better quality of life. These results suggest that, in patients with multiple bone fracture, the rewiring approach does not promote physiological bone consolidation, whereas the muscle flap reconstruction can assure more physiological ventilatory dynamics