1,235 research outputs found

    Iterative adaption of the bidimensional wall of the French T2 wind tunnel around a C5 axisymmetrical model: Infinite variation of the Mach number at zero incidence and a test at increased incidence

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    The top and bottom two-dimensional walls of the T2 wind tunnel are adapted through an iterative process. The adaptation calculation takes into account the flow three-dimensionally. This method makes it possible to start with any shape of walls. The tests were performed with a C5 axisymmetric model at ambient temperature. Comparisons are made with the results of a true three-dimensional adaptation

    About low field memory and negative magnetization in semiconductors and polymers

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    Ginzburg-Landau bulk magnetization of itinerant electrons can provide a negative effective field in the Weiss model by coupling to localized magnetic moments. The coupling enforces remnant magnetization, which can be negative or positive depending on the sample magnetic history. Stable magnetic susceptibility of coupled nonequilibrium subsystems with magnetization reversal is always positive. Gauss-scale fields could be expected for switching between negative and positive remnant moments in semiconductors with coupling at ambient temperatures. Negative magnetization in ultra-high conducting polymers is also discussed within the developed framework.Comment: 8 pages, no figure

    Too Many Fish in the Sea: A Motivational Examination of the Choice Overload Experience

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    Evidence supports that being overwhelmed by many choice options predicts negative consequences. However, there is uncertainty regarding the effects of choice overload on two key motivational dimensions: (1) the extent to which people view their decision as subjectively valuable (versus not), and (2) the extent to which people view themselves as capable (versus incapable) of reaching a good decision. While evaluating their options and while deciding, we assessed theory-based cardiovascular responses reflecting these dimensions. A meta-analysis across two experiments found that participants who made a final selection from many options—relative to those who chose from few or rated many—exhibited cardiovascular responses consistent with greater task engagement (i.e., perceiving greater subjective value), as well as greater threat (i.e., perceiving fewer resources to manage situational demands). The current work suggests a novel motivational account of choice overload, providing insight into the nature and timing of this experience as it occurs

    Implicitly imprinting the past on the present: Automatic partner attitudes and the transition to parenthood

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    A new model is proposed to explain how automatic partner attitudes affect how couples cope with major life transitions. The Automatic Partner Attitudes in Transition (APAT) model assumes that people simultaneously possess contextualized automatic attitudes toward their partner that can differ substantively in valence pre- and post-transition. It further assumes that evaluatively inconsistent pre- and post-transition automatic partner attitudes elicit heightened behavioral angst or uncertainty, self-protective behavior in response to risk, and relationship distress. A longitudinal study of the transition to first parenthood supported the model. People with evaluatively inconsistent automatic partner attitudes, whether more negative pre-transition and positive post-transition, or more positive pre-transition and negative post-transition, exhibited heightened evidence of cardiovascular threat discussing conflicts, increased self-protective behavior in response to parenting-related transgressions in daily interaction, and steeper declines in relationship well-being in the year following the transition to parenthood

    Weighted gene co-expression network analysis to explain the relationship between plasma total carotenoids and lipid profile

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    Background: Variability in circulating carotenoids may be attributable to several factors including, among others, genetic variants and lipid profile. However, relatively few studies have considered the impact of gene expression in the inter-individual variability in circulating carotenoids. Most studies considered expression of genes individually and ignored their high degree of interconnection. Weighted gene co-expression network analysis (WGCNA) is a systems biology method used for finding gene clusters with highly correlated expression levels and for relating them to phenotypic traits. The objective of the present observational study is to examine the relationship between plasma total carotenoid concentrations and lipid profile using WGCNA. Results: Whole blood expression levels of 533 probes were associated with plasma total carotenoids. Among the four WGCNA distinct modules identified, turquoise, blue, and brown modules correlated with plasma high-density lipoprotein cholesterol (HDL-C) and total cholesterol. Probes showing a strong association with HDL-C and total cholesterol were also the most important elements of the brown and blue modules. A total of four and 29 hub genes associated with total carotenoids were potentially related to HDL-C and total cholesterol, respectively. Conclusions: Expression levels of 533 probes were associated with plasma total carotenoid concentrations. Using WGCNA, four modules and several hub genes related to lipid and carotenoid metabolism were identified. This integrative analysis provides evidence for the potential role of gene co-expression in the relationship between carotenoids and lipid concentrations. Further studies and validation of the hub genes are needed

    Genetic and common environmental contributions to familial resemblances in plasma carotenoid concentrations in healthy families

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    Carotenoids have shown an interindividual variability that may be due to genetic factors. The only study that has reported heritability of serum α- and β-carotene has not considered the environmental component. This study aimed to estimate the contribution of both genetic and common environmental effects to the variance of carotenoid concentrations and to test whether their phenotypic correlations with cardiometabolic risk factors are explained by shared genetic and environmental effects. Plasma carotenoid concentrations (α-carotene, β-carotene, β-cryptoxanthin, lutein, lycopene, zeaxanthin, and total carotenoids) of 48 healthy subjects were measured. Heritability estimates of carotenoid concentrations were calculated using the variance component method. Lutein and lycopene showed a significant familial effect (p = 6 × 10−6 and 0.0043, respectively). Maximal heritability, genetic heritability, and common environmental effect were computed for lutein (88.3%, 43.8%, and 44.5%, respectively) and lycopene (45.2%, 0%, and 45.2%, respectively). Significant phenotypic correlations between carotenoid concentrations and cardiometabolic risk factors were obtained for β-cryptoxanthin, lycopene, and zeaxanthin. Familial resemblances in lycopene concentrations were mainly attributable to common environmental effects, while for lutein concentrations they were attributable to genetic and common environmental effects. Common genetic and environmental factors may influence carotenoids and cardiometabolic risk factors, but further studies are needed to better understand the potential impact on disease development

    Network Analysis of the potential role of DNA methylation in the relationship between plasma carotenoids and lipid profile

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    Abstract: Variability in plasma carotenoids may be attributable to several factors including genetic variants and lipid profile. Until now, the impact of DNA methylation on this variability has not been widely studied. Weighted gene correlation network analysis (WGCNA) is a systems biology method used for finding gene clusters (modules) with highly correlated methylation levels and for relating them to phenotypic traits. The objective of the present study was to examine the role of DNA methylation in the relationship between plasma total carotenoid concentrations and lipid profile using WGCNA in 48 healthy subjects. Genome-wide DNA methylation levels of 20,687 out of 472,245 CpG sites in blood leukocytes were associated with total carotenoid concentrations. Using WGCNA, nine co-methylation modules were identified. A total of 2734 hub genes (17 unique top hub genes) were potentially related to lipid profile. This study provides evidence for the potential implications of gene co-methylation in the relationship between plasma carotenoids and lipid profile. Further studies and validation of the hub genes are needed

    Infrastructure needs on latitudinal and longitudinal chains of co-located ground-based observations

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    The generation, propagation, and dissipation of atmospheric planetary waves (PW), tides, and gravity waves (GW) constitute the primary mechanism that transfers energy and momentum from the atmosphere to space. While single-location ground-based observations have been making successful measurements of such waves over the past decades, NSF funded ground-based observations are not yet systematically distributed at the same latitude or the same longitude, despite the importance of latitudinal and longitudinal dependence of dynamical processes like large scale wave propagation, interaction, and dissipation. This white paper discusses the significance and potential of coordinating a chain of ground-based instruments with the current large facilities to extend the latitudinal and longitudinal observational coverage in the American sector (both South and North America). We further discuss the benefits of co-locating heterogeneous instruments with different techniques and different temporal/spatial resolution/coverage, for instance, radio instruments (e.g., ISR, HF radar, meteor radar), optical instruments (e.g., FPI, lidar, airglow imager), magnetometers, ionosondes, sounding rockets and so on

    Modeling and Experimental Validation of a Transient Direct Expansion Heat Pump

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    Geothermal heat pump technology is currently one of the most interesting technologies used to heat buildings. There are two designs used in the industry: geothermal heat pump using a secondary ground loop and Direct Expansion (DX) ground source heat pump. The latter is less used, possibly because less research has been carried out for the design of this kind of heat pump. In this paper, a transient model using the Comsol Multiphysic of a DX ground heat pump is presented in heating mode with R22, and a comparison with experimental results is presented with a 24-hour test. It is shown that the model was adequately validated by our experiment with only a maximum difference of 15%. Following this validation, a parametric analysis was realised on the geometry of the borehole. This study concluded that to have the best heat extraction of the ground, the pipes shank spacing need to be important without increasing the borehole diameter.Article History: Received January 16th 2017; Received in revised form May 28th 2017; Accepted June 6th 2017; Available onlineHow to Cite This Article: Rousseau, C., Fannou, J.L.C., Lamarche, L. and Kajl, S. (2017) Modeling and Experimental Validation of a Transient Direct Expansion Heat Pump. International Journal of Renewable Energy Development, 6(2), 145-155.https://doi.org/10.14710/ijred.6.2.145-15
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