On Dirac Zero Modes in Hyperdiamond Model

Using the SU(5) symmetry of the 4D hyperdiamond and results on the study of 4D graphene given in "Four Dimensional Graphene" (L.B Drissi, E.H Saidi, M. Bousmina, CPM-11-01, Phys. Rev. D (2011)), we engineer a class of 4D lattice QCD fermions whose Dirac operators have two zero modes. We show that generally the zero modes of the Dirac operator in hyperdiamond fermions are captured by a tensor {\Omega}_{{\mu}}^{l} with 4\times5 complex components linking the Euclidean SO(4) vector {\mu}; and the 5-dimensional representation of SU(5). The Bori\c{c}i-Creutz (BC) and the Karsten-Wilzeck (KW) models as well as their Dirac zero modes are rederived as particular realizations of {\Omega}_{{\mu}}^{l}. Other features are also given. Keywords: Lattice QCD, Bori\c{c}i-Creutz and Karsten-Wilzeck models, 4D hyperdiamond, 4D graphene, SU(5) Symmetry.Comment: LaTex, 28 pages, To appear in Phys Rev

Systematic Review of Laser and Other Light Therapy for the Management of Oral Mucositis in Cancer Patients

Background The aim of this study was to review the available literature and define clinical practice guidelines for the use of laser and other light therapies for the prevention and treatment of oral mucositis. Methods A systematic review was conducted by the Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology. The body of evidence for each intervention, in each cancer treatment setting, was assigned an evidence level. Based onthe evidence level, one of the following three guideline determinations was possible: recommendation, suggestion, and no guideline possible. Results A new recommendation was made for low-level laser (wavelength at 650 nm, power of 40 mW, and each square centimeter treated with the required time to a tissue energy dose of 2 J/cm2 (2 s/point)) for the prevention of oral mucositis in adult patients receiving hematopoietic stem cell transplantation conditioned with high-dose chemotherapy, with or without total body irradiation. A new suggestion was made for low-level laser (wavelength around 632.8 nm) for the prevention of oral mucositis in patients undergoing radiotherapy, without concomitant chemotherapy, for head and neck cancer. No guideline was possible in other populations and for other light sources due to insufficient evidence. Conclusions The increasing evidence in favor of low-level laser therapy allowed for the development of two new guidelines supporting this modality in the populations listed above. Evidence for other populations was also generally encouraging over a range of wavelengths and intensities. However, additional well-designed research is needed to evaluate the efficacy of laser and other light therapies in various cancer treatment settings

Modelo termo hidráulico solar para colectores solares de convección natural

We present the development of a thermal-hydraulic-solar model (MTHS) for design and numerical simulation of solar thermal collectors. The MTHS is a powerful tool that, not only simulates the above, but also allows to extrapolate collector behavior for different weather patterns for any day of the year, at any latitude of the country, thus allowing maximize the efficiency of the collector in each particular case. The model takes into account in its equations the characteristic parameters of a collector, such as: optical efficiency and the overall heat loss coefficient, what defined efficiency collector. The model also includes the geometrical parameters of a collector, such as length and diameter of the absorber (values that determine the pressure drop of hydrodynamic circuit), it also uses the positioning data such as azimuth angle of the absorber, and the height of tank (values of which depends heavily the buoyant force needed to establish the natural convection in the collector).Se presenta el desarrollo de un modelo termo-hidráulico solar (MTHS) para el diseño y simulación numérica de colectores solares térmicos. El MTHS es una poderosa herramienta que permite simular el comportamiento de un colector en diferentes patrones para cualquier día del año, en cualquier latitud del país, permitiendo maximizar el rendimiento en cada caso particular. El modelo tiene en cuenta en sus ecuaciones los parámetros característicos de un colector: la eficiencia óptica y el coeficiente de pérdida global de calor, ambos definen la eficiencia del mismo. Además contempla sus parámetros geométricos constructivos, como ser longitud y diámetro del absorbedor (valores que determinan la pérdida de carga hidrodinámica del sistema), y área de colección; además de las variables de ubicación como el ángulo de elevación acimutal del absorbedor, y la altura o desnivel del tanque (valor del cual depende fuertemente la fuerza boyante que origina la convección natural en el colector).Tema 3: Energía solar, aplicaciones térmicas y químicas.Facultad de Arquitectura y Urbanism

Modelo termo hidráulico solar para colectores solares de convección natural

We present the development of a thermal-hydraulic-solar model (MTHS) for design and numerical simulation of solar thermal collectors. The MTHS is a powerful tool that, not only simulates the above, but also allows to extrapolate collector behavior for different weather patterns for any day of the year, at any latitude of the country, thus allowing maximize the efficiency of the collector in each particular case. The model takes into account in its equations the characteristic parameters of a collector, such as: optical efficiency and the overall heat loss coefficient, what defined efficiency collector. The model also includes the geometrical parameters of a collector, such as length and diameter of the absorber (values that determine the pressure drop of hydrodynamic circuit), it also uses the positioning data such as azimuth angle of the absorber, and the height of tank (values of which depends heavily the buoyant force needed to establish the natural convection in the collector).Se presenta el desarrollo de un modelo termo-hidráulico solar (MTHS) para el diseño y simulación numérica de colectores solares térmicos. El MTHS es una poderosa herramienta que permite simular el comportamiento de un colector en diferentes patrones para cualquier día del año, en cualquier latitud del país, permitiendo maximizar el rendimiento en cada caso particular. El modelo tiene en cuenta en sus ecuaciones los parámetros característicos de un colector: la eficiencia óptica y el coeficiente de pérdida global de calor, ambos definen la eficiencia del mismo. Además contempla sus parámetros geométricos constructivos, como ser longitud y diámetro del absorbedor (valores que determinan la pérdida de carga hidrodinámica del sistema), y área de colección; además de las variables de ubicación como el ángulo de elevación acimutal del absorbedor, y la altura o desnivel del tanque (valor del cual depende fuertemente la fuerza boyante que origina la convección natural en el colector).Tema 3: Energía solar, aplicaciones térmicas y químicas.Facultad de Arquitectura y Urbanism

Nuevo colector solar térmico de bajo costo de flujo forzado autónomo por panel fotovoltaico

The development of simple and inexpensive design of solar thermal collectors is presented. They are based on a long LDPE hose, that works by forced recirculation assisted by a pump which is powered by a little photovoltaic panel. The feasibility of this simple and autonomous thermoidraulic configuration was experimentally demonstrated. A prototype, of 50 liters with 50 meters of hose (3/4") and a 2 W pump which is operated by 3W 12 V panel, has been elaborated. The prototype has worked with an average efficiency of 37%, reaching the water, on a winter day with solar average irradiances of 700 W / m2, a maximum temperature of 48 °C.Se presenta el desarrollo de colectores solares térmicos de bajo costo y simple diseño, basados en una larga manguera de PEBD que operan por recirculación forzada asistida por mini bomba regulada y alimentada por panel fotovoltaico. Se demostró experimentalmente la factibilidad de esta configuración termohidráulica simple y autónoma. Un prototipo (50 litros y 50 metros manguera de ¾”, bomba de 2W y panel fotovoltaico de 3W en 12 voltios) obtuvo eficiencias promedio del 37%, calentando agua a 48°C en invierno en Salta con irradiancias de 700 W/m2.Tema 3: Energía solar, aplicaciones térmicas y químicas.Facultad de Arquitectura y Urbanism

Modelo termo hidráulico solar para colectores solares de convección natural

We present the development of a thermal-hydraulic-solar model (MTHS) for design and numerical simulation of solar thermal collectors. The MTHS is a powerful tool that, not only simulates the above, but also allows to extrapolate collector behavior for different weather patterns for any day of the year, at any latitude of the country, thus allowing maximize the efficiency of the collector in each particular case. The model takes into account in its equations the characteristic parameters of a collector, such as: optical efficiency and the overall heat loss coefficient, what defined efficiency collector. The model also includes the geometrical parameters of a collector, such as length and diameter of the absorber (values that determine the pressure drop of hydrodynamic circuit), it also uses the positioning data such as azimuth angle of the absorber, and the height of tank (values of which depends heavily the buoyant force needed to establish the natural convection in the collector).Se presenta el desarrollo de un modelo termo-hidráulico solar (MTHS) para el diseño y simulación numérica de colectores solares térmicos. El MTHS es una poderosa herramienta que permite simular el comportamiento de un colector en diferentes patrones para cualquier día del año, en cualquier latitud del país, permitiendo maximizar el rendimiento en cada caso particular. El modelo tiene en cuenta en sus ecuaciones los parámetros característicos de un colector: la eficiencia óptica y el coeficiente de pérdida global de calor, ambos definen la eficiencia del mismo. Además contempla sus parámetros geométricos constructivos, como ser longitud y diámetro del absorbedor (valores que determinan la pérdida de carga hidrodinámica del sistema), y área de colección; además de las variables de ubicación como el ángulo de elevación acimutal del absorbedor, y la altura o desnivel del tanque (valor del cual depende fuertemente la fuerza boyante que origina la convección natural en el colector).Tema 3: Energía solar, aplicaciones térmicas y químicas.Facultad de Arquitectura y Urbanism

Nuevo colector solar térmico de bajo costo de flujo forzado autónomo por panel fotovoltaico

The development of simple and inexpensive design of solar thermal collectors is presented. They are based on a long LDPE hose, that works by forced recirculation assisted by a pump which is powered by a little photovoltaic panel. The feasibility of this simple and autonomous thermoidraulic configuration was experimentally demonstrated. A prototype, of 50 liters with 50 meters of hose (3/4") and a 2 W pump which is operated by 3W 12 V panel, has been elaborated. The prototype has worked with an average efficiency of 37%, reaching the water, on a winter day with solar average irradiances of 700 W / m2, a maximum temperature of 48 °C.Se presenta el desarrollo de colectores solares térmicos de bajo costo y simple diseño, basados en una larga manguera de PEBD que operan por recirculación forzada asistida por mini bomba regulada y alimentada por panel fotovoltaico. Se demostró experimentalmente la factibilidad de esta configuración termohidráulica simple y autónoma. Un prototipo (50 litros y 50 metros manguera de ¾”, bomba de 2W y panel fotovoltaico de 3W en 12 voltios) obtuvo eficiencias promedio del 37%, calentando agua a 48°C en invierno en Salta con irradiancias de 700 W/m2.Tema 3: Energía solar, aplicaciones térmicas y químicas.Facultad de Arquitectura y Urbanism

Nuevo colector solar térmico de bajo costo de flujo forzado autónomo por panel fotovoltaico

The development of simple and inexpensive design of solar thermal collectors is presented. They are based on a long LDPE hose, that works by forced recirculation assisted by a pump which is powered by a little photovoltaic panel. The feasibility of this simple and autonomous thermoidraulic configuration was experimentally demonstrated. A prototype, of 50 liters with 50 meters of hose (3/4") and a 2 W pump which is operated by 3W 12 V panel, has been elaborated. The prototype has worked with an average efficiency of 37%, reaching the water, on a winter day with solar average irradiances of 700 W / m2, a maximum temperature of 48 °C.Se presenta el desarrollo de colectores solares térmicos de bajo costo y simple diseño, basados en una larga manguera de PEBD que operan por recirculación forzada asistida por mini bomba regulada y alimentada por panel fotovoltaico. Se demostró experimentalmente la factibilidad de esta configuración termohidráulica simple y autónoma. Un prototipo (50 litros y 50 metros manguera de ¾”, bomba de 2W y panel fotovoltaico de 3W en 12 voltios) obtuvo eficiencias promedio del 37%, calentando agua a 48°C en invierno en Salta con irradiancias de 700 W/m2.Tema 3: Energía solar, aplicaciones térmicas y químicas.Facultad de Arquitectura y Urbanism

Assessing the discordance rate between local and central HER2 testing in women with locally determined HER2-negative breast cancer.

BackgroundThe importance of human epidermal growth factor receptor 2 (HER2) as a prognostic and predictive marker in invasive breast cancer is well established. Accurate assessment of HER2 status is essential to determine optimal treatment options.MethodsBreast cancer tumor tissue samples from the VIRGO observational cohort tissue substudy that were locally HER2-negative were retested centrally with both US Food and Drug Administration (FDA)-approved immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) assays, using FDA-approved assay cutoffs; results were compared.ResultsOf the 552 unique patient samples centrally retested with local HER2-negative results recorded, tumor samples from 22 (4.0%) patients were determined to be HER2-positive (95% confidence interval [CI] = 2.5%-5.7%). Of these, 18 had been tested locally by only one testing methodology; 15 of 18 were HER2-positive after the central retesting, based on the testing methodology not performed locally. Compared with the 530 patients with centrally confirmed HER2-negative tumors, the 22 patients with centrally determined HER2-positive tumors were younger (median age 56.5 versus 60.0 years) and more likely to have ER/PR-negative tumors (27.3% versus 22.3%). These patients also had shorter median progression-free survival (6.4 months [95% CI = 3.8-15.9 months] versus 9.1 months [95% CI = 8.3-10.3 months]) and overall survival (25.9 months [95% CI = 13.8-not estimable] versus 27.9 months [95% CI = 25.0-32.9 months]).ConclusionsThis study highlights the limitations of employing just one HER2 testing methodology in current clinical practice. It identifies a cohort of patients who did not receive potentially efficacious therapy because their tumor HER2-positivity was not determined by the test initially used. Because of inherent limitations in testing methodologies, it is inadvisable to rely on a single test to rule out potential benefit from HER2-targeted therapy