3,527 research outputs found
Methodology for urban rail and construction technology research and development planning
A series of transit system visits, organized by the American Public Transit Association (APTA), was conducted in which the system operators identified the most pressing development needs. These varied by property and were reformulated into a series of potential projects. To assist in the evaluation, a data base useful for estimating the present capital and operating costs of various transit system elements was generated from published data. An evaluation model was developed which considered the rate of deployment of the research and development project, potential benefits, development time and cost. An outline of an evaluation methodology that considered benefits other than capital and operating cost savings was also presented. During the course of the study, five candidate projects were selected for detailed investigation; (1) air comfort systems; (2) solid state auxiliary power conditioners; (3) door systems; (4) escalators; and (5) fare collection systems. Application of the evaluation model to these five examples showed the usefulness of modeling deployment rates and indicated a need to increase the scope of the model to quantitatively consider reliability impacts
Citizen science against the plastic soup: background, motivation and expectations of volunteers studying plastic pollution on Dutch riverbanks
In the field of investigating and addressing plastic pollution, the public is increasingly involved in research as citizen scientists. Long-term monitoring for this topic is needed, and recruiting and retaining volunteers is challenging. Therefore, it is important to learn more about the demographic background, motivations and expectations of involved citizen scientists, and if these change during participation. Our research studied these aspects of the citizen scientists in the Dutch Clean Rivers project, who monitor plastic pollution on riverbanks. Participants (n = 122) completed pre- and post-survey after one year of the project. While there was no gender bias, the participants were mostly middle-aged and highly educated, and almost half had previous experience with scientific research. Their motivation to participate was mostly activistic, as they wanted to tackle the source of plastic pollution and contribute to solutions. More personal motivations, such as wanting to learn more and because it is fun to do scientific research, decreased significantly after one year of participation. Their expectations were in line with the main motivations. Understanding the background, motivations and expectations of volunteers helps this project, and the field of citizen science in plastic pollution research
Cadaveric Renal transplantation with Cyclosporine: Experiences in 148 patients at a single institution.
Eikonal Approximation to 5D Wave Equations as Geodesic Motion in a Curved 4D Spacetime
We first derive the relation between the eikonal approximation to the Maxwell
wave equations in an inhomogeneous anisotropic medium and geodesic motion in a
three dimensional Riemannian manifold using a method which identifies the
symplectic structure of the corresponding mechanics. We then apply an analogous
method to the five dimensional generalization of Maxwell theory required by the
gauge invariance of Stueckelberg's covariant classical and quantum dynamics to
demonstrate, in the eikonal approximation, the existence of geodesic motion for
the flow of mass in a four dimensional pseudo-Riemannian manifold. These
results provide a foundation for the geometrical optics of the five dimensional
radiation theory and establish a model in which there is mass flow along
geodesics. Finally we discuss the case of relativistic quantum theory in an
anisotropic medium as well. In this case the eikonal approximation to the
relativistic quantum mechanical current coincides with the geodesic flow
governed by the pseudo-Riemannian metric obtained from the eikonal
approximation to solutions of the Stueckelberg-Schr\"odinger equation. This
construction provides a model for an underlying quantum mechanical structure
for classical dynamical motion along geodesics on a pseudo-Riemannian manifold.
The locally symplectic structure which emerges is that of Stueckelberg's
covariant mechanics on this manifold.Comment: TeX file. 17 pages. Rewritten for clarit
Technologies for Detecting Botulinum Neurotoxins in Biological and Environmental Matrices
Biomonitoring of food and environmental matrices is critical for the rapid and sensitive diagnosis, treatment, and prevention of diseases caused by toxins. The U.S. Centers for Disease Control and Prevention (CDC) has noted that toxins from bacteria, fungi, algae, and plants present an ongoing public health threat, especially since some of these toxins could compromise security of the food supply. Botulinum neurotoxins (BoNTs), produced by Clostridium spp., are among those bacterial toxins that pose life-threatening danger to humans. BoNTs inhibit the release of acetylcholine at peripheral cholinergic nerve terminals and cause flaccid paralysis. BoNTs are grouped in seven serotypes and many subtypes within these groups. Rapid and accurate identification of these toxins in contaminated food as well as in environmental matrices can help direct treatment. Herein, we discuss current methods to detect BoNTs with a focus on how these technologies have been used to identify toxins in various food and environmental matrices. We also discuss the emergence of new serotypes and subtypes of BoNTs and the increasing number of cases of botulism in wildlife. Finally, we consider how environmental changes impact food safety for humans and present new challenges for detection technology
Footprints of Statistical Anisotropies
We propose and develop a formalism to describe and constrain statistically
anisotropic primordial perturbations. Starting from a decomposition of the
primordial power spectrum in spherical harmonics, we find how the temperature
fluctuations observed in the CMB sky are directly related to the coefficients
in this harmonic expansion. Although the angular power spectrum does not
discriminate between statistically isotropic and anisotropic perturbations, it
is possible to define analogous quadratic estimators that are direct measures
of statistical anisotropy. As a simple illustration of our formalism we test
for the existence of a preferred direction in the primordial perturbations
using full-sky CMB maps. We do not find significant evidence supporting the
existence of a dipole component in the primordial spectrum.Comment: 26 pages, 5 double figures. Uses RevTeX
Learning from the early adopters: developing the digital practitioner
This paper explores how Sharpe and Beetham’s Digital Literacies Framework which was derived to model students’ digital literacies, can be applied to lecturers’ digital literacy practices. Data from a small-scale phenomenological study of higher education lecturers who used Web 2.0 in their teaching and learning practices are used to examine if this pyramid model represents their motivations for adopting technology-enhanced learning in their pedagogic practices. The paper argues that whilst Sharpe and Beetham’s model has utility in many regards, these lecturers were mainly motivated by the desire to achieve their pedagogic goals rather than by a desire to become a digital practitioner
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