Towards the First Galaxies

The formation of the first galaxies at redshifts z~10-15 signaled the transition from the simple initial state of the universe to one of ever increasing complexity. We here review recent progress in understanding their assembly process with numerical simulations, starting with cosmological initial conditions and modelling the detailed physics of star formation. In particular, we study the role of HD cooling in ionized primordial gas, the impact of UV radiation produced by the first stars, and the propagation of the supernova blast waves triggered at the end of their brief lives. We conclude by discussing promising observational diagnostics that will allow us to probe the properties of the first galaxies, such as their contribution to reionization and the chemical abundance pattern observed in extremely low-metallicity stars.Comment: 12 pages, 14 figures, appeared in "First Stars III", eds. B. O'Shea, A. Heger and T. Abel, a high resolution version (highly recommended) can be found at http://www.ita.uni-heidelberg.de/~tgreif/files/gjb07.pd

The First Supernova Explosions: Energetics, Feedback, And Chemical Enrichment

We perform three-dimensional smoothed particle hydrodynamics simulations in a realistic cosmological setting to investigate the expansion, feedback, and chemical enrichment properties of a 200M(circle dot) pair-instability supernova in the high-redshift universe. We find that the SN remnant propagates for a Hubble time at z similar or equal to 20 to a final mass-weighted mean shock radius of 2.5 kpc (proper), roughly half the size of the H II region, and in this process sweeps up a total gas mass of 2: 5; 10(5) M-circle dot. The morphology of the shock becomes highly anisotropic once it leaves the host halo and encounters filaments and neighboring minihalos, while the bulk of the shock propagates into the voids of the intergalactic medium. The SN entirely disrupts the host halo and terminates further star formation for at least 200 Myr, while in our specific case it exerts positive mechanical feedback on neighboring minihalos by shock-compressing their cores. In contrast, we do not observe secondary star formation in the dense shell via gravitational fragmentation, due to the previous photoheating by the progenitor star. We find that cooling by metal lines is unimportant for the entire evolution of the SN remnant, while the metal-enriched, interior bubble expands adiabatically into the cavities created by the shock, and ultimately into the voids with a maximum extent similar to the final mass-weighted mean shock radius. Finally, we conclude that dark matter halos of at least M-vir greater than or similar to 10(8) M-circle dot must be assembled to recollect all components of the swept-up gas.Astronom

The Birth of a Galaxy: Primordial Metal Enrichment and Stellar Populations

By definition, Population III stars are metal-free, and their protostellar collapse is driven by molecular hydrogen cooling in the gas-phase, leading to large characteristic masses. Population II stars with lower characteristic masses form when the star-forming gas reaches a critical metallicity of 10^{-6} - 10^{-3.5} Z_\odot. We present an adaptive mesh refinement radiation hydrodynamics simulation that follows the transition from Population III to II star formation. The maximum spatial resolution of 1 comoving parsec allows for individual molecular clouds to be well-resolved and their stellar associations to be studied in detail. We model stellar radiative feedback with adaptive ray tracing. A top-heavy initial mass function for the Population III stars is considered, resulting in a plausible distribution of pair-instability supernovae and associated metal enrichment. We find that the gas fraction recovers from 5 percent to nearly the cosmic fraction in halos with merger histories rich in halos above 10^7 solar masses. A single pair-instability supernova is sufficient to enrich the host halo to a metallicity floor of 10^{-3} Z_\odot and to transition to Population II star formation. This provides a natural explanation for the observed floor on damped Lyman alpha (DLA) systems metallicities reported in the literature, which is of this order. We find that stellar metallicities do not necessarily trace stellar ages, as mergers of halos with established stellar populations can create superpositions of t-Z evolutionary tracks. A bimodal metallicity distribution is created after a starburst occurs when the halo can cool efficiently through atomic line cooling.Comment: 11 pages, 7 figures; replaced with accepted version to ApJ; additional movies and images can be found at http://www.astro.princeton.edu/~jwise/research/GalaxyBirth.htm

Validating international CanMEDS-based standards defining education and safe practice of nurse anesthetists.

AIM To investigate whether the CanMEDS-based International Federation of Nurse Anesthetists' Standards could adequately define the scope of practice and reliably be used to train and evaluate Swiss nurse anesthetists (NAs). BACKGROUND Although nurse anesthetists represent a majority of the global workforce in anesthesia, policies that define the scope of practice are frequently non-existent. In low- and middle-income countries, the lack of anesthesia providers with adequate training is a major challenge. INTRODUCTION Despite stringent training requirements, the scope of practice of Swiss nurse anesthetists is actually not defined. Therefore, we surveyed and assessed whether nurse anesthetists felt that the professional competencies outlined in this framework were aligned with their clinical practice. METHODS A cross-sectional survey investigated Swiss nurse anesthetists' relevance ratings of 76 competencies of the International Federation of Nurse Anesthetists according to their professional practice. Cronbach's alpha coefficients were used to determine the internal consistency of the competencies, as well as factor analyses to assess construct validity of these competencies integrated into the CanMEDS roles model. RESULTS Participants rated the Standards overall as very relevant with high reliability. Factor analyses provided evidence of construct validity of these. DISCUSSION The International Federation of Nurse Anesthetists' Standards of Practice provide a highly relevant framework and a valuable set of competencies for the scope of practice of Swiss nurse anesthetists, which enabled translation from global guides to local national standards. CONCLUSION AND IMPLICATION FOR NURSING AND HEALTH POLICY Adopted by low- and middle-income countries or countries where national standards are non-existent, this survey could introduce national and local policies at minimally acceptable standards of care for nurse anesthetists worldwide. The above standards have the potential to align education, outcomes and assessment of nurse anesthetists with the needs of national healthcare systems

Dislocations and melting in two dimensions: The critical region

A new analysis is presented of the critical-point behavior of two-dimensional melting in the Kosterlitz-Thouless-Nelson-Halperin-Young theory. The analysis confirms the Kosterlitz-Thouless-Nelson-Halperin-Young critical-point exponent, ν̅=0.36963…, but also gives a criterion for its own range of validity amounting to t>10^13 lattice spacings. The implications of these results for experimental verification are discussed

Real-time visualization of ultrasound-guided retrobulbar blockade: an imaging study

Background Retrobulbar anaesthesia allows eye surgery in awake patients. Severe complications of the blind techniques are reported. Ultrasound-guided needle introduction and direct visualization of the spread of local anaesthetic may improve quality and safety of retrobulbar anaesthesia. Therefore, we developed a new ultrasound-guided technique using human cadavers. Methods In total, 20 blocks on both sides in 10 embalmed human cadavers were performed. Using a small curved array transducer and a long-axis approach, a 22 G short bevel needle was introduced under ultrasound guidance lateral and caudal of the eyeball until the needle tip was seen 2 mm away from the optic nerve. At this point, 2 ml of contrast dye as a substitute for local anaesthetic was injected. Immediately after the injection, the spread of the contrast dye was documented by means of CT scans performed in each cadaver. Results The CT scans showed the distribution of the contrast dye in the muscle cone and behind the posterior sclera in all but one case. No contrast dye was found inside the optic nerve or inside the eyeball. In one case, there could be an additional trace of contrast dye behind the orbita. Conclusions Our new ultrasound-guided technique has the potential to improve safety and efficacy of the procedure by direct visualization of the needle placement and the distribution of the injected fluid. Furthermore, the precise injection near the optic nerve could lead to a reduction of the amount of the local anaesthetic needed with fewer related complication