Revisi?n de la Gu?a de Pr?ctica Cl?nica sobre el manejo de la Depresi?n en el adulto (2014) del Programa de GPC en el SNS

A Gu?a de Pr?ctica Cl?nica sobre o Manexo da Depresi?n no Adulto publicouse no ano 2014, formando parte do Programa de Gu?as no Sistema Nacional de Sa?de. O prop?sito desta gu?a era mellorar a atenci?n prestada aos pacientes con depresi?n no ?mbito de atenci?n primaria e hospitalaria, a trav?s de recomendaci?ns, un algoritmo terap?utico, indicadores de calidade e informaci?n para pacientes e familiares. O tempo transcorrido desde a s?a publicaci?n, a nova evidencia publicada e a magnitude do problema, fan relevante a s?a revisi?n. O obxectivo deste informe ? documentar o procedemento para a revisi?n da vixencia da gu?a e os principais resultados e conclusi?ns do grupo de traballo.La Gu?a de Pr?ctica Cl?nica sobre el Manejo de la Depresi?n en el Adulto se public? en el a?o 2014, formando parte del Programa de Gu?as en el Sistema Nacional de Salud. El prop?sito de esta gu?a era mejorar la atenci?n prestada a los pacientes con depresi?n en el ?mbito de atenci?n primaria y hospitalaria, a trav?s de recomendaciones, un algoritmo terap?utico, indicadores de calidad e informaci?n para pacientes y familiares. El tempo transcurrido desde su publicaci?n, la nueva evidencia publicada y la magnitud del problema, hacen relevante su revisi?n. El objectivo de este informe es documentar el procedemiento para la revisi?n de la vigencia de la gu?a y los principales resultados y conclusiones del grupo de trabajo

Characteristics of joint involvement and relationship with systemic inflammation in systemic sclerosis: result from the EULAR scleroderma trial and research (EUSTAR) database.

To determine the prevalence of and independent factors associated with joint involvement in a large population of patients with systemic sclerosis (SSc). METHODS: This study was cross-sectional, based on data collected on patients included in the European League Against Rheumatism (EULAR) Scleroderma Trials and Research (EUSTAR) registry. We queried this database to extract data regarding global evaluation of patients with SSc and the presence of any clinical articular involvement: synovitis (tender and swollen joints), tendon friction rubs (rubbing sensation detected as the tendon was moved), and joint contracture (stiffness of the joints that decreased their range of motion). Overall joint involvement was defined by the occurrence of synovitis and/or joint contracture and/or tendon friction rubs. RESULTS: We recruited 7286 patients with SSc; their mean age was 56 +/- 14 years, disease duration 10 +/- 9 years, and 4210 (58%) had a limited cutaneous disease subset. Frequencies of synovitis, tendon friction rubs, and joint contractures were 16%, 11%, and 31%, respectively. Synovitis, tendon friction rubs, and joint contracture were more prevalent in patients with the diffuse cutaneous subset and were associated together and with severe vascular, muscular, renal, and interstitial lung involvement. Moreover, synovitis had the highest strength of association with elevated acute-phase reactants taken as the dependent variable. CONCLUSION: Our results highlight the striking level of articular involvement in SSc, as evaluated by systematic examination in a large cohort of patients with SSc. Our data also show that synovitis, joint contracture, and tendon friction rubs are associated with a more severe disease and with systemic inflammation

Neotropical xenarthrans: a dataset of occurrence of xenarthran species in the Neotropics.

International audienceXenarthrans—anteaters, sloths, and armadillos—have essential functions forecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosys-tem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts withdomestic dogs, these species have been threatened locally, regionally, or even across their fulldistribution ranges. The Neotropics harbor 21 species of armadillos, 10 anteaters, and 6 sloths.Our data set includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae(3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data onDasypus pilo-sus(Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized,but new genetic studies have revealed that the group is represented by seven species. In thisdata paper, we compiled a total of 42,528 records of 31 species, represented by occurrence andquantitative data, totaling 24,847 unique georeferenced records. The geographic range is fromthe southern United States, Mexico, and Caribbean countries at the northern portion of theNeotropics, to the austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regardinganteaters,Myrmecophaga tridactylahas the most records (n=5,941), andCyclopessp. havethe fewest (n=240). The armadillo species with the most data isDasypus novemcinctus(n=11,588), and the fewest data are recorded forCalyptophractus retusus(n=33). Withregard to sloth species,Bradypus variegatushas the most records (n=962), andBradypus pyg-maeushas the fewest (n=12). Our main objective with Neotropical Xenarthrans is to makeoccurrence and quantitative data available to facilitate more ecological research, particularly ifwe integrate the xenarthran data with other data sets of Neotropical Series that will become available very soon (i.e., Neotropical Carnivores, Neotropical Invasive Mammals, andNeotropical Hunters and Dogs). Therefore, studies on trophic cascades, hunting pressure,habitat loss, fragmentation effects, species invasion, and climate change effects will be possiblewith the Neotropical Xenarthrans data set. Please cite this data paper when using its data inpublications. We also request that researchers and teachers inform us of how they are usingthese data