In vivo formation of natural HgSe nanoparticles in the liver and brain of pilot whales

Acknowledgments Z.G. thanks to the College of Physical Sciences at University of Aberdeen and Chevron USA for the provided studentship. P.M.K. is the recipient of an Australian Research Council Future Fellowship (FT120100277). Parts of this research were undertaken on the XFM beamline at the Australian Synchrotron, Victoria, Australia. The assistance of Daryl Howard (XFM beamline, Australian Synchrotron) is acknowledged. Although EPA contributed to this article, the research presented was not performed by or funded by EPA and was not subject to EPA's quality system requirements. Consequently, the views, interpretations, and conclusions expressed in this article are solely those of the authors and do not necessarily reflect or represent EPA's views or policies. MRCAT operations are supported by the Department of Energy and the MRCAT member institutions. This research used resources of the Advanced Photon Source, a U.S. Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE-AC02-06CH11357. The authors declare no competing financial interests. F.L.R. and A.B. acknowledge Scottish Marine Animal Stranding Scheme and Marine Scotland for funding. Author Contributions E.M.K and J.F. designed the experiments. Z.G. measured total Hg and conducted Hg speciation. Total Se was determined by A.R. and Z.G. M.M.L. performed Se speciation and 2D imaging by LA-ICP-MS was done by D.S.U. XANES was performed by K.S. and XRF by E.L. and P.M.K. Samples were obtained by E.M.K. through A.B. and age determination was done by F.R. spICP-MS was performed by E.H.L., K.L., G.W. and Z.G. The manuscript was written by Z.G. and all authors discussed the results and commented on the manuscript.Peer reviewedPublisher PD

Possible link between Hg and Cd accumulation in the brain of long-finned pilot whales (Globicephala melas)

Acknowledgements M. M. Lawan for his helpful discussions about Se and advice on ICP-MS. C. C. Brombach for his introduction to CV-AFS and to D. Bellis for valuable comments and reviewing the English language in the manuscript. ZG would also like to thank the College of Physical Sciences at the University of Aberdeen and Chevron USA for the provided studentship. FLR and AB acknowledge Scottish Marine Animal Stranding Scheme and Marine Scotland for the funding.Peer reviewedPostprin