332 research outputs found

    “Urgent Dental Care” – A preclinical patient case scenario as an aid to clinic preparation for treating a patient with urgent dental care needs

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    BackgroundPre-clinical student competencies are usually assessed in only one specific area and not contextualized in a patient care scenario. Exposing preclinical students to a high fidelity simulated urgent care patient scenario will help the student develop critical thinking and intuitive dental treatment skills that will prepare them for actual urgent dental care (UDC) treatment in the clinic. AimsDental students, in the preclinical years, have difficulty in applying various disciplines of dentistry to an actual patient. The goal of this exercise is to contextualize several disciplines (diagnosis, material selection, oral pathology, electronic record keeping, patient interview and critical thinking) into a real patient case. The hypothesis is that providing a preclinical urgent care session in this manner will better prepare students for clinical UDC treatment.MethodsAn urgent care patient scenario was developed that integrated multiple disciplines and contextualized common urgent clinical situations that are encountered daily, focusing on interviewing skills, basic diagnostic skills, manipulation of electronic patient records, material selection and defence of selection, image and data procurement, prescription writing, critical decision making, oral medicine diagnosis, treatment planning for a focused need, and performance of dental treatment. Second year dental students are required to interview a first time (walk-in) urgent care patient to determine the chief complaint, diagnose the urgent problem (based on information obtained by interviewing the patient) and to make critical patient care decisions and self-assess their performance. Results Students generally completed the session on time and in a satisfactory fashion. Preparation for the session was key and faculty calibration was essential. ConclusionCompletion of this case scenario better prepared the students for the clinic as indicated by student self-assessment, post course satisfaction surveys, narrative comments, and faculty assessments

    Capitol East Neighborhood Charter Plan Update

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    The first Capitol East Neighborhood Action Plan, completed in December of 1990, was successful in achieving its goals. Neighborhood accomplishments borne of the first plan include the following: the construction of a new elementary school (Capitol View); housing redevelopment on Walnut Street between East 15th and East 16th Streets; improvements to Stewart Square Park; designing attractive green spaces in highly visible areas;establishing an organized an “alley clean up” process in one alley each month during the SCRUB season;and the Neighborhood Development Corporation’s commercial development along East Grand Avenue.This second neighborhood revitalization process is a pilot program designed to review and update the plans of charter neighborhoods whose plans are more than 10 years old.https://lib.dr.iastate.edu/resilientneighborhoods_plans/1001/thumbnail.jp

    Acoustic and visual study of bubble formation processes in bubble columns staged with fibrous catalytic layers

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    High-speed images of bubbly flow coupled with simultaneous passive acoustic measurements were carried out in a bubble column staged with structured fibrous catalysts. Local observations made with a high-speed camera system allow a detailed understanding of the influence of fabric structure on bubble formation processes and the detn. of the Sauter bubble diam. With acoustic measurements, the building frequency of bubble swarm formation is identified to be a linear function of the superficial gas velocity. Due to bubble size and building frequency of bubble swarm the percentage of simultaneously operative sites (holes at which bubbles were formed simultaneously) is calcd. [on SciFinder (R)

    Mass spectrometry study of ascorbyl palmitate as an agent for nanosomes formation

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    Background. Study of properties and intermolecular interactions of biologically active compounds which can be used for the purposes of transmembrane drugs delivery is a topical task of modern molecular biophysics. Ascorbyl Palmitate (AP) as a fat-soluble form of vitamin C has recently attracted attention as a promising agent for formation of nanosomes for the “fat insoluble” drug molecules transfer through membranes. However, AP is not sufficiently characterized by up-to-date soft ionization mass spectrometric techniques. Objectives. The aim of the present work is to characterize AP and its intermolecular interactions by a number of mass spectrometric techniques: Electrospray Ionization (ESI), Laser Desorption/Ionization (LDI) and Matrix-Assisted Laser Desorption/Ionization (MALDI). The comparison of these techniques applicability to the study of AP intermolecular interactions as a drug delivery assisting agent is scheduled. Methods. ESI mass spectra are obtained with triple quadrupole Micromass Quattro mass spectrometer. LDI and MALDI experiments are performed by Autoflex II mass spectrometer. Results. In the ESI experiments in the positive ion mode abundant peaks of protonated and cationized AP molecules as well as the peaks of AP clusters nAP‱H+ and nAP‱Na+ (n=2Ă·4) are revealed in the mass spectra. This result testifies to the formation of stable noncovalent complexes of the AP molecules in the polar media and confirms the AP ability of formation nanosomes for drug delivery. Analysis of LDI and MALDI mass spectra of AP in positive and negative ion modes shows that in the presence of molecular ions of AP, the peaks of AP dimers or larger AP clusters are not recorded. The ESI probing of the model system containing AP and dipalmitoylphosphatidylcholine (DPPC) reveals stable AP‱DPPC‱H+ complex which models the AP intermolecular interactions with the phospholipid components of biomembranes and/or liposomes under AP functioning as a drug delivery assisting agent. Conclusions. The current study demonstrates the applicability of all tested mass spectrometric techniques for AP identification in solutions and solid phase, while for the purpose of examining of the AP noncovalent complexes formation and study of AP interactions with biomolecules the ESI is defined as the most effective technique

    Towards Open and Equitable Access to Research and Knowledge for Development

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    Leslie Chan and colleagues discuss the value of open access not just for access to health information, but also for transforming structural inequity in current academic reward systems and for valuing scholarship from the South
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