Chemical Composition,Anti-Inflammatory,Antioxidant and Antimicrobial Activity of Essential Oil from Aerial Parts of Chaerophyllum aromaticum L. from Turkey

The essential oil obtained by hydrodistillation from the aerial parts of Chaerophyllum aromaticum L. was analyzed by GC and GC/MS. Anti-inflammatory activity was evaluated by lipoxygenase inhibition assay. Antioxidant activity was tested by DPPH method. Antimicrobial activity was carried out using microdilution method against seven bacteria and one fungus. The yield of light yellow-coloured essential oil was 1.1 % Eighteen compounds were identified in oil of the aerial parts representing 99.2 % of the C. aromaticum oil. Sabinene (28.1 %), terpinolene (16.7 %) and gamma-terpinene (16.1 %) were characterized as the main compounds. The oil exhibited remarkable anti-inflammatory activity with an IC50, value of 63.62 +/- 1.26 mu g/ml. The oil at a concentration of 20 mg/mL inhibited DPPH radical by 2.06 %. The oil exhibited moderate antibacterial activity against Staphylococcus aureus ATCC 29213 (MIC: 156 mu g/ml) and Sepidermidis ATCC 12228 (MIC: 625 mu g/ml). The results showed that C. aromaticum essential oil was rich in monoterpene compounds and had moderate antibacterial activity against Staphylococcus strains as well as having significant anti-inflammatory activity

Diterpenoid Alkaloids from the Roots of Aconitum cochleare

From the roots Aconitum cochleare Woroschin, collected in Turkey, a new diterpenoid alkaloid named acochlearine has been isolated along with the known diterpenoid alkaloids talatisamine, 14-O-acetyltalatisamine, senbusine C and condelphine. The structure for acochlearine was established on the basis of 1H, 13C, DEPT, homonuclear 1H COSY, NOESY, HSQC and HMBC NMR studies

Norditerpenoid alkaloids from the aerial parts of Aconitum cochleare WOROSCHIN

From the aerial parts of Aconitum cochleare WOROSCHIN, two new norditerpenoid alkaloids named aconitilearine (1) and N- deethylmethyllycaconitine (2) were isolated along with the eight known norditerpenoid alkaloids 3-10. The structures for the new compounds were established on the basis of 1H, 13C, DEPT, homonuclear 1H,1H-COSY, NOESY, HSQC, and HMBC NMR studies. © 2006 Verlag Helvetica Chimica Acta AG

Alkaloids from Consolida olopetala

Three norditerpenoid alkaloids, delphatine (1), delcaroline (2), and browniine (3), and three diterpenoid alkaloids, hetisine (4), dehydronapelline (5), and 12-epidehydronapelline (6), have been isolated and identified from the aerial parts of Consolida olopetala (Boiss.) Hayek (Ranunculaceae). © 2006 Taylor & Francis Group, LLC

Diterpenoid alkaloids from the roots of Aconitum cochleare

From the roots Aconitum cochleare Woroschin, collected in Turkey, a new diterpenoid alkaloid named acochlearine has been isolated along with the known diterpenoid alkaloids talatisamine, 14-O-acetyltalatisamine, senbusine C and condelphine. The structure for acochlearine was established on the basis of 1H, 13C, DEPT, homonuclear 1H COSY, NOESY, HSQC and HMBC NMR studies