Grid service orchestration using the Business Process Execution Language (BPEL)

Modern scientific applications often need to be distributed across grids. Increasingly applications rely on services, such as job submission, data transfer or data portal services. We refer to such services as grid services. While the invocation of grid services could be hard coded in theory, scientific users want to orchestrate service invocations more flexibly. In enterprise applications, the orchestration of web services is achieved using emerging orchestration standards, most notably the Business Process Execution Language (BPEL). We describe our experience in orchestrating scientific workflows using BPEL. We have gained this experience during an extensive case study that orchestrates grid services for the automation of a polymorph prediction application

Burden of podoconiosis in poor rural communities in Guliso woreda, western Ethiopia

Background. Podoconiosis is an environmental lymphoedema affecting people living and working barefoot on irritant red clay soil. Podoconiosis is relatively well described in southern Ethiopia, but remains neglected in other parts of the Ethiopian highlands. This study aimed to assess the burden of podoconiosis in rural communities in western Ethiopia. Methodology/Principal Findings. A cross-sectional study was conducted in Gulliso woreda (district), west Ethiopia. A household survey in the 26 rural kebeles (villages) of this district was conducted to identify podoconiosis patients and to measure disease prevalence. A more detailed study was done in six randomly selected kebeles to describe clinical features of the disease, patients’ experiences of foot hygiene, and shoe wearing practice. 1,935 cases of podoconiosis were registered, giving a prevalence of 2.8%. The prevalence was higher in those aged 15 – 64 years (5.2%) and in females than males (prevalence ratio 2.6:1). 90.3% of patients were in the 15 – 64 year age group. In the detailed study, 335 cases were interviewed and their feet assessed. The majority of patients were farmers, uneducated, and poor. Two-third of patients developed the disease before the age of thirty. Almost all patients (97.0%) had experienced adenolymphangitis (ALA - red, hot legs, swollen and painful groin) at least once during the previous year. Patients experienced an average of 5.5 ALA episodes annually, each of average 4.4 days, thus 24 working days were lost annually. The incidence of ALA in podoconiosis patients was higher than that reported for filariasis in other countries. Shoe wearing was limited mainly due to financial problems. Conclusions. We have documented high podoconiosis prevalence, frequent adenolymphangitis and high disease-related morbidity in west Ethiopia. Interventions must be developed to prevent, treat and control podoconiosis, one of the core neglected tropical diseases in Ethiopia

Panax ginseng has no effect on indices of glucose regulation following acute or chronic ingestion in healthy volunteers

In the absence of effective pharmacotherapy for diabetes there has been an increase in the use of, and research into, alternative treatment strategies. These include exercise, dietary interventions and the use of supplements including extracts of ginseng. Two separate, placebo-controlled, double-blind, cross-over studies investigating the effects of chronic ingestion of Panax ginseng (study 1 used G115, study 2 used Cheong Kwan Jang) on glycated Hb (HbA1c; study 1, n 18; study 2, n 11), fasting plasma insulin (study 1, n 17; study 2, n 12), fasting plasma glucose and postprandial response (following breakfast) (study 1, n 23; study 2, n 14) in healthy volunteers are reported. In both studies it was found that Panax ginseng had no effect on any gluco-regulatory parameter investigated. These results are not consistent with those reported for a diabetic sample (albeit using slightly different outcomes). These results would suggest that chronic use of Panax ginseng by non-diabetic individuals will have little long-term effect on glucose regulation. The benefits to glucose regulation associated with long-term ginseng use may only be present in populations with compromised glucose control; however, further research is needed to confirm such a speculation

Turbulence and Transport During Guide-Field Reconnection at the Magnetopause

We analyze the development and influence of turbulence in three-dimensional particle-in-cell simulations of guide-field magnetic reconnection at the magnetopause with parameters based on observations of an electron diffusion region by the Magnetospheric Multiscale (MMS) mission. Along the separatrices the turbulence is a variant of the lower hybrid drift instability (LHDI) that produces electric field fluctuations with amplitudes much greater than the reconnection electric field. The turbulence controls the scale length of the density and current profiles while enabling significant transport across the magnetopause despite the electrons remaining frozen-in to the magnetic field. Near the X-line the electrons are not frozen-in and the turbulence, which differs from the LHDI, makes a significant net contribution to the generalized Ohm's law through an anomalous viscosity. The characteristics of the turbulence and associated particle transport are consistent with fluctuation amplitudes in the MMS observations. However, for this event the simulations suggest that the MMS spacecraft were not close enough to the core of the electron diffusion region to identify the region where anomalous viscosity is important

Flow properties of a series of experimental thermoplastic polymides

The softening temperature to degradation temperature range of the polymers was about 440 to 650 K. All of the polymers retained small amounts of solvent as indicated by an increase in T(sub g) as the polymers were dried. The flow properties showed that all three polymers had very high apparent viscosities and would require high pressures and/or high temperatures and/or long times to obtain adequate flow in prepregging and molding. Although none was intended for such application, two of the polymers were combined with carbon fibers by solution prepregging. The prepregs were molded into laminates at temperatures and times, the selection of which was guided by the results from the flow measurements. These laminates had room temperature short beam shear strength similar to that of carbon fiber laminates with a thermosetting polyimide matrix. However, the strength had considerable scatter, and given the difficult processing, these polymides probably would not be suitable for continuous fiber composites

Tidal interaction in binary black hole inspiral

In rotating viscous fluid stars, tidal torque leads to an exchange of spin and orbital angular momentum. The horizon of a black hole has an effective viscosity that is large compared to that of stellar fluids, and an effective tidal torque may lead to important effects in the strong field interaction at the endpoint of the inspiral of two rapidly rotating holes. In the most interesting case both holes are maximally rotating and all angular momenta (orbital and spins) are aligned. We point out here that in such a case (i) the transfer of angular momentum may have an important effect in modifying the gravitational wave ``chirp'' at the endpoint of inspiral. (ii) The tidal transfer of spin energy to orbital energy may increase the amount of energy being radiated. (iii) Tidal transfer in such systems may provide a mechanism for shedding excess angular momentum. We argue that numerical relativity, the only tool for determining the importance of tidal torque, should be more specifically focused on binary configurations with aligned, large, angular momenta.Comment: 5 pages, 2 figure