62,056 research outputs found
The Core of the Participatory Budgeting Problem
In participatory budgeting, communities collectively decide on the allocation
of public tax dollars for local public projects. In this work, we consider the
question of fairly aggregating the preferences of community members to
determine an allocation of funds to projects. This problem is different from
standard fair resource allocation because of public goods: The allocated goods
benefit all users simultaneously. Fairness is crucial in participatory decision
making, since generating equitable outcomes is an important goal of these
processes. We argue that the classic game theoretic notion of core captures
fairness in the setting. To compute the core, we first develop a novel
characterization of a public goods market equilibrium called the Lindahl
equilibrium, which is always a core solution. We then provide the first (to our
knowledge) polynomial time algorithm for computing such an equilibrium for a
broad set of utility functions; our algorithm also generalizes (in a
non-trivial way) the well-known concept of proportional fairness. We use our
theoretical insights to perform experiments on real participatory budgeting
voting data. We empirically show that the core can be efficiently computed for
utility functions that naturally model our practical setting, and examine the
relation of the core with the familiar welfare objective. Finally, we address
concerns of incentives and mechanism design by developing a randomized
approximately dominant-strategy truthful mechanism building on the exponential
mechanism from differential privacy
Lateral-Pressure Profiles in Cholesterol-DPPC Bilayers
By means of atomistic molecular dynamics simulations, we study
cholesterol-DPPC (dipalmitoyl phosphatidylcholine) bilayers of different
composition, from pure DPPC bilayers to a 1:1 mixture of DPPC and cholesterol.
The lateral-pressure profiles through the bilayers are computed and separated
into contributions from the different components. We find that the pressure
inside the bilayer changes qualitatively for cholesterol concentrations of
about 20% or higher. The pressure profile then turns from a rather flat shape
into an alternating sequence of regions with large positive and negative
lateral pressure. The changes in the lateral-pressure profile are so
characteristic that specific interaction between cholesterol and molecules such
as membrane proteins mediated solely via the lateral-pressure profile might
become possible
Algebras for Agent Norm-Regulation
An abstract architecture for idealized multi-agent systems whose behaviour is
regulated by normative systems is developed and discussed. Agent choices are
determined partially by the preference ordering of possible states and
partially by normative considerations: The agent chooses that act which leads
to the best outcome of all permissible actions. If an action is non-permissible
depends on if the result of performing that action leads to a state satisfying
a condition which is forbidden, according to the norms regulating the
multi-agent system. This idea is formalized by defining set-theoretic
predicates characterizing multi-agent systems. The definition of the predicate
uses decision theory, the Kanger-Lindahl theory of normative positions, and an
algebraic representation of normative systems.Comment: 25 page
TREX1 DNA exonuclease deficiency, accumulation of single stranded DNA and complex human genetic disorders
Aicardi-Goutieres syndrome (AGS) is an unusual condition that clinically mimics a congenital viral infection. Several genes have recently been implicated in the aetiology of this disorder. One of these genes encodes the DNA exonuclease TREX1. Recent work from Yang, Lindahl and Barnes has provided insight into the cellular consequence of TREX1-deficiency. They found that TREX1-deficiency resulted in the intracellular accumulation of single stranded DNA resulting in chronic activation of the DNA damage response network, even in cells from Trex1-mutated AGS patients. Here, I summarise their findings and discuss them in context with the other AGS causative genes which encode subunits of the RNase H2 complex. I describe mechanisms by which the inappropriate intracellular accumulation of nucleic acid species might deleteriously impact upon normal cell cycle progression. Finally, using the example of Systemic Lupus Erythematosus (SLE), I also summarise the evidence suggesting that the failure to process intermediates of nucleic acid metabolism can result in the activation of uncontrolled autoimmunity
Revisiting the Economics of Privacy: Population Statistics and Confidentiality Protection as Public Goods
This paper has been replaced with http://digitalcommons.ilr.cornell.edu/ldi/37.
We consider the problem of the public release of statistical information about a population–explicitly accounting for the public-good properties of both data accuracy and privacy loss. We first consider the implications of adding the public-good component to recently published models of private data publication under differential privacy guarantees using a Vickery-Clark-Groves mechanism and a Lindahl mechanism. We show that data quality will be inefficiently under-supplied. Next, we develop a standard social planner’s problem using the technology set implied by (ε, δ)-differential privacy with (α, β)-accuracy for the Private Multiplicative Weights query release mechanism to study the properties of optimal provision of data accuracy and privacy loss when both are public goods. Using the production possibilities frontier implied by this technology, explicitly parameterized interdependent preferences, and the social welfare function, we display properties of the solution to the social planner’s problem. Our results directly quantify the optimal choice of data accuracy and privacy loss as functions of the technology and preference parameters. Some of these properties can be quantified using population statistics on marginal preferences and correlations between income, data accuracy preferences, and privacy loss preferences that are available from survey data. Our results show that government data custodians should publish more accurate statistics with weaker privacy guarantees than would occur with purely private data publishing. Our statistical results using the General Social Survey and the Cornell National Social Survey indicate that the welfare losses from under-providing data accuracy while over-providing privacy protection can be substantial
- …