898 research outputs found
The Sloan Lens ACS Survey. VI: Discovery and analysis of a double Einstein ring
We report the discovery of two concentric Einstein rings around the
gravitational lens SDSSJ0946+1006, as part of the Sloan Lens ACS Survey. The
main lens is at redshift zl=0.222, while the inner ring (1) is at zs1=0.609 and
Einstein radius . The wider image separation () of the outer ring (2) implies that it is at higher redshift. Its
detection in the F814W filter implies zs2<6.9. The configuration can be well
described by a total density profile with
and velocity dispersion \sigma_{SIE}=287\pm5\kms. [...] We consider whether
this configuration can be used to constrain cosmological parameters exploiting
angular distance ratios entering the lens equations. Constraints for
SDSSJ0946+1006, are uninteresting due to the sub-optimal lens and source
redshifts. We then consider the perturbing effect of the mass associated with
Ring 1 building a double lens plane compound lens model. This introduces minor
changes to the mass of the main lens and allows to estimate the mass of Ring 1
(\sigma_{SIE,s1}=94\pm30\kms). We examine the prospects of doing cosmography
with a sample of 50 double lenses, expected from future space based surveys
such as DUNE or JDEM. Taking full account of the model uncertainties, such a
sample could be used to measure and with 10% accuracy, for a
flat cosmology
Comparison of acute non-visual bright light responses in patients with optic nerve disease, glaucoma and healthy controls.
This study examined the effect of optic nerve disease, hence retinal ganglion cell loss, on non-visual functions related to melanopsin signalling. Test subjects were patients with bilateral visual loss and optic atrophy from either hereditary optic neuropathy (nâ=â11) or glaucoma (nâ=â11). We measured melatonin suppression, subjective sleepiness and cognitive functions in response to bright light exposure in the evening. We also quantified the post-illumination pupil response to a blue light stimulus. All results were compared to age-matched controls (nâ=â22). Both groups of patients showed similar melatonin suppression when compared to their controls. Greater melatonin suppression was intra-individually correlated to larger post-illumination pupil response in patients and controls. Only the glaucoma patients demonstrated a relative attenuation of their pupil response. In addition, they were sleepier with slower reaction times during nocturnal light exposure. In conclusion, glaucomatous, but not hereditary, optic neuropathy is associated with reduced acute light effects. At mild to moderate stages of disease, this is detected only in the pupil function and not in responses conveyed via the retinohypothalamic tract such as melatonin suppression
A More Fundamental Plane
We combine strong-lensing masses with SDSS stellar velocity dispersions and
HST-ACS effective (half-light) radii for 36 lens galaxies from the Sloan Lens
ACS (SLACS) Survey to study the mass dependence of mass-dynamical structure in
early-type galaxies. We find that over a 180--390 km/s range in velocity
dispersion, structure is independent of lensing mass to within 5%. This result
suggests a systematic variation in the total (i.e., luminous plus dark matter)
mass-to-light ratio as the origin of the tilt of the fundamental plane (FP)
scaling relationship between galaxy size, velocity dispersion, and surface
brightness. We construct the FP of the lens sample, which we find to be
consistent with the FP of the parent SDSS early-type galaxy population, and
present the first observational correlation between mass-to-light ratio and
residuals about the FP. Finally, we re-formulate the FP in terms of surface
mass density rather than surface brightness. By removing the complexities of
stellar-population effects, this mass-plane formulation will facilitate
comparison to numerical simulations and possible use as a cosmological distance
indicator.Comment: 4+epsilon pages, 1 figure, emulateapj. Revised version accepted for
publication in the ApJ Letter
Addition of Bevacizumab to Temsirolimus in Kidney Cancer Patients
Treatment of metastatic kidney cancer has changed dramatically in the past years with the use of VEGF-targeted therapies and mTOR inhibitors. However, resistance occurs. We report here two cases of patients who benefited, both on disease control and side effects, from the addition of bevacizumab to temsirolimus, after progression on the mTOR inhibitor alone
The SWELLS survey. IV. Precision measurements of the stellar and dark matter distributions in a spiral lens galaxy
We construct a fully self-consistent mass model for the lens galaxy J2141 at
z=0.14, and use it to improve on previous studies by modelling its
gravitational lensing effect, gas rotation curve and stellar kinematics
simultaneously. We adopt a very flexible axisymmetric mass model constituted by
a generalized NFW dark matter halo and a stellar mass distribution obtained by
deprojecting the MGE fit to the high-resolution K'-band LGSAO imaging data of
the galaxy, with the (spatially constant) M/L ratio as a free parameter. We
model the stellar kinematics by solving the anisotropic Jeans equations. We
find that the inner logarithmic slope of the dark halo is weakly constrained
(gamma = 0.82^{+0.65}_{-0.54}), and consistent with an unmodified NFW profile.
We infer the galaxy to have (i) a dark matter fraction within 2.2 disk radii of
0.28^{+0.15}_{-0.10}, independent of the galaxy stellar population, implying a
maximal disk for J2141; (ii) an apparently uncontracted dark matter halo, with
concentration c_{-2} = 7.7_{-2.5}^{+4.2} and virial velocity v_{vir} =
242_{-39}^{+44} km/s, consistent with LCDM predictions; (iii) a slightly oblate
halo (q_h = 0.75^{+0.27}_{-0.16}), consistent with predictions from
baryon-affected models. Comparing the stellar mass inferred from the combined
analysis (log_{10} Mstar/Msun = 11.12_{-0.09}^{+0.05}) with that inferred from
SPS modelling of the galaxies colours, and accounting for a cold gas fraction
of 20+/-10%, we determine a preference for a Chabrier IMF over Salpeter IMF by
a Bayes factor of 5.7 (substantial evidence). We infer a value beta_{z} = 1 -
sigma^2_{z}/sigma^2_{R} = 0.43_{-0.11}^{+0.08} for the orbital anisotropy
parameter in the meridional plane, in agreement with most studies of local disk
galaxies, and ruling out at 99% CL that the dynamics of this system can be
described by a two-integral distribution function. [Abridged]Comment: Accepted for publication in MNRAS. 17 pages, 9 figure
EXCASAFEZONE
Excavation work takes place almost continually in most cities around the Western hemisphere. Many cities are already full of infrastructures, buried networks, and street furniture, so excavation work is not without any thread to the operator and surrounding environment. Small construction sites, for example, are often constrained by operating infrastructure on surface level and underground. Although different agencies and network owners have information about the location of the objects that put excavation work at risk, this information is not centralized. Different organizations manage location information of buried cables, unexploded ordnance, and pollution, for example. This significantly complicates the early-stage planning and last minute risk assessment processes because professionals need to manually collect, assess, and integrate data about subsurface objects into a comprehensive risk assessment. To smoothen this process, ExcaSafeZone project, therefore, develops a system that collects location data, defines expert-based rules for safety risk assessment, and that synthesizes this into an open source prototype that visualized safety risks on a heat map.
 
Cross-talk between signaling pathways leading to defense against pathogens and insects
In nature, plants interact with a wide range of organisms, some of which
are harmful (e.g. pathogens, herbivorous insects), while others are beneficial
(e.g. growth-promoting rhizobacteria, mycorrhizal fungi, and predatory
enemies of herbivores). During the evolutionary arms race between plants
and their attackers, primary and secondary immune responses evolved to
recognize common or highly specialized features of microbial pathogens
(Chisholm et al., 2006), resulting in sophisticated mechanisms of defense
Dual Averaging Method for Online Graph-structured Sparsity
Online learning algorithms update models via one sample per iteration, thus
efficient to process large-scale datasets and useful to detect malicious events
for social benefits, such as disease outbreak and traffic congestion on the
fly. However, existing algorithms for graph-structured models focused on the
offline setting and the least square loss, incapable for online setting, while
methods designed for online setting cannot be directly applied to the problem
of complex (usually non-convex) graph-structured sparsity model. To address
these limitations, in this paper we propose a new algorithm for
graph-structured sparsity constraint problems under online setting, which we
call \textsc{GraphDA}. The key part in \textsc{GraphDA} is to project both
averaging gradient (in dual space) and primal variables (in primal space) onto
lower dimensional subspaces, thus capturing the graph-structured sparsity
effectively. Furthermore, the objective functions assumed here are generally
convex so as to handle different losses for online learning settings. To the
best of our knowledge, \textsc{GraphDA} is the first online learning algorithm
for graph-structure constrained optimization problems. To validate our method,
we conduct extensive experiments on both benchmark graph and real-world graph
datasets. Our experiment results show that, compared to other baseline methods,
\textsc{GraphDA} not only improves classification performance, but also
successfully captures graph-structured features more effectively, hence
stronger interpretability.Comment: 11 pages, 14 figure
Observation of sub-Bragg diffraction of waves in crystals
We investigate the diffraction conditions and associated formation of
stopgaps for waves in crystals with different Bravais lattices. We identify a
prominent stopgap in high-symmetry directions that occurs at a frequency below
the ubiquitous first-order Bragg condition. This sub-Bragg diffraction
condition is demonstrated by reflectance spectroscopy on two-dimensional
photonic crystals with a centred rectangular lattice, revealing prominent
diffraction peaks for both the sub-Bragg and first-order Bragg condition. These
results have implications for wave propagation in 2 of the 5 two-dimensional
Bravais lattices and 7 out of 14 three-dimensional Bravais lattices, such as
centred rectangular, triangular, hexagonal and body-centred cubic
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