Εκκρεμείς συμβάσεις στις διαδικασίες αφερεγγυότητας: Συμπεράσματα με βάση τη δικαιοσυγκριτική επισκόπηση

Η παρούσα διπλωματική εργασία πραγματεύεται το κρίσιμο και διαχρονικό ζήτημα των εκκρεμών συμβάσεων στις διαδικασίες αφερεγγυότητας. Η έννοια του «ανεκπλήρωτου» της παροχής των συμβαλλόμενων μερών αποτελεί τον βασικό άξονα προβληματισμού, αποτυπώνοντας ταυτόχρονα και τη δυσκολία καθιέρωσης ενός τυπικού – τεχνικού ορισμού για τον προσδιορισμό της έννοιας της εκκρεμούς συμβάσεως. Περαιτέρω, η φύση και η λειτουργία της εκκρεμούς συμβάσεως στο πλαίσιο των διαδικασιών αφερεγγυότητας εξετάζεται, εκτός από την ελληνική, και σε άλλες πέντε εθνικές δικαιοταξίες, με ιδιαίτερη έμφαση στο Αμερικανικό δίκαιο. Τέλος, επιχειρείται μία δικαιοσυγκριτική επισκόπηση των εξετασθέντων νομικών συστημάτων, με απώτερο στόχο της εξαγωγή κρίσιμων συμπερασμάτων.This dissertation addresses the crucial and timeless issue of executory contracts in insolvency proceedings. The concept of "unperformed" obligations of the contracting parties is the main focus of reflection, while also reflecting the difficulty of establishing a formal - technical definition for defining the concept of executory contract. Furthermore, the nature and operation of the executory contract in the context of insolvency proceedings are examined, in addition to the Greek one, in five other national jurisdictions, with particular emphasis on American law. Finally, a comparative overview of the examined legal systems is attempted, with the ultimate goal of drawing critical conclusions

A novel R-package graphic user interface for the analysis of metabonomic profiles

Background Analysis of the plethora of metabolites found in the NMR spectra of biological fluids or tissues requires data complexity to be simplified. We present a graphical user interface (GUI) for NMR-based metabonomic analysis. The "Metabonomic Package" has been developed for metabonomics research as open-source software and uses the R statistical libraries. /Results The package offers the following options: Raw 1-dimensional spectra processing: phase, baseline correction and normalization. Importing processed spectra. Including/excluding spectral ranges, optional binning and bucketing, detection and alignment of peaks. Sorting of metabolites based on their ability to discriminate, metabolite selection, and outlier identification. Multivariate unsupervised analysis: principal components analysis (PCA). Multivariate supervised analysis: partial least squares (PLS), linear discriminant analysis (LDA), k-nearest neighbor classification. Neural networks. Visualization and overlapping of spectra. Plot values of the chemical shift position for different samples. Furthermore, the "Metabonomic" GUI includes a console to enable other kinds of analyses and to take advantage of all R statistical tools. /Conclusion We made complex multivariate analysis user-friendly for both experienced and novice users, which could help to expand the use of NMR-based metabonomics

A MRI and polarized gases compatible respirator and gas administrator for the study of the small animal lung : volume measurement and control

We have developed over the past years an experimental magnetic resonance imaging (MRI) and polarized gases compatible mechanical respirator for the study of the small experimental animal. The respirator has been successfully used for experiments both in the MRI setting for polarized (3)He, (19)F, and proton imaging as well as for functional measurements of the lungs. The new main pneumatic valve with the two integrated sensors for simultaneous lung pressure and volume measurements and the proportional valve to set the tidal volume of the respiration are described. It is shown how the device measures and controls the tidal volume of the lungs

Regulatory and Functional Involvement of Long Non-Coding RNAs in DNA Double-Strand Break Repair Mechanisms

Protection of genome integrity is vital for all living organisms, particularly when DNA double-strand breaks (DSBs) occur. Eukaryotes have developed two main pathways, namely Non-Homologous End Joining (NHEJ) and Homologous Recombination (HR), to repair DSBs. While most of the current research is focused on the role of key protein players in the functional regulation of DSB repair pathways, accumulating evidence has uncovered a novel class of regulating factors termed non-coding RNAs. Non-coding RNAs have been found to hold a pivotal role in the activation of DSB repair mechanisms, thereby safeguarding genomic stability. In particular, long non-coding RNAs (lncRNAs) have begun to emerge as new players with vast therapeutic potential. This review summarizes important advances in the field of lncRNAs, including characterization of recently identified lncRNAs, and their implication in DSB repair pathways in the context of tumorigenesis

Multifocal Osteomyelitis Localization after Pyomyositis in Children: Importance of Timely Response

Pyomyositis is a rare bacterial infection that used to prevail in tropical areas for the past century. Nowadays though, more and more cases are reported in high-temperature climate areas. Diagnosis is often delayed due to the variance in clinical presentation, the challenging nature of physical examination of a child, and lack of specific laboratory investigating tools. When the diagnosis is delayed, the outcome may be unpredictable. Multifocal localization through hematogenous or direct spread that may affect the skeletal bone tissue is common. Timely diagnosis and response is a race against septic shock. We present a case series of seven children diagnosed with pyomyositis due to Staphylococcus aureus. High or less clinical suspicion has obviously affected the final outcome since two patients who were not treated in time were subjected to a life-threatening hazard. Five patients who were diagnosed and treated within the first three days after initiation of their symptoms had a predictable and good outcome without complications