Evaluation of fungicides for the management of sclerotinia blight of peanut

Three trials were conducted in the Burnett region of southern Queensland, Australia, in the 1993–94 and 1994–95 seasons to determine the efficacy of fluazinam, procymidone, and iprodione for managing sclerotinia blight of peanut. Different combinations of rates, nozzle types, and spraying times were used in each trial. Two or 3 sprays of fluazinam at 0.75 and 1.0 kg a.i./ha, and of procymidone at 0.688 and 0.75 kg a.i./ha, were the most effective combinations that reduced disease incidence and increased yield. Iprodione at rates up to 0.5 kg a.i./ha did not significantly improve the yield compared with unsprayed treatments in any trial. In one trial at Tingoora in 1994–95, pre-infection treatments in which the first spray of fluazinam or procymidone was applied before symptoms appeared were more effective than post-infection treatments in which the first spray was applied soon after symptoms were seen. At J. Bjelke-Petersen Research Station (JBPRS) in 1994–95, a banded spray of procymidone at 0.688 kg a.i./ha using a single flat-fan 8004VB nozzle centred over the row significantly increased yield and reduced disease incidence compared with a spray using 3 hollow-cone nozzles (HB4-70) per row, with 1 nozzle over the row and 1 drop nozzle on each side of the row directed at the bases of the plants. At JBPRS in 1993–94, a band spray of fluazinam at 0.333 kg a.i./120 L.ha, applied with a single flat-fan 80015EVB nozzle immediately after the appearance of symptoms, was as effective in reducing the rate of disease development for 3 weeks, as was a directed application using three 80015EVB nozzles at the same time and concentration, but at 3 times the rate per area (1.0 kg a.i./360 L.ha)

Maternal mycotoxin exposure and adverse pregnancy outcomes: a systematic review

Mycotoxin exposure from food occurs globally but is more common in hot humid environments, especially in low-income settings, and might affect pregnancy outcomes. This study aimed to synthesize the evidence from epidemiological studies on the relationship between maternal or fetal exposure to different mycotoxins and the occurrence of adverse pregnancy outcomes. Multiple databases were systematically searched up to December 2018 to identify studies that assessed the association between mycotoxin exposure in pregnant women or fetuses and at least one pregnancy outcome. Studies were appraised and results were synthesized using standard methods for conducting systematic reviews. This review identified and included 17 relevant studies. There is some evidence to suggest that exposure to various Aspergillus mycotoxins (e.g., aflatoxin) during pregnancy may impair intrauterine fetal growth and promote neonatal jaundice. Findings were inconclusive concerning the influence of aflatoxin exposure on perinatal death and preterm birth. Only two studies assessed effects of maternal exposure to Fusarium mycotoxins (e.g., fumonisin) on adverse pregnancy outcomes. These studies found that maternal fumonisin exposure may be associated with hypertensive emergencies in pregnancy and with neural tube defects. Studies using grain farming and weather conditions as a proxy measure for mycotoxin exposure found that such exposure was associated with an increased risk of preterm birth and late-term miscarriage. In conclusion, there is already some evidence to suggest that exposure to mycotoxins during pregnancy may have detrimental effects on pregnancy outcomes. However, given the limited number of studies, especially on effects of Fusarium mycotoxins, more studies are needed for a more comprehensive understanding of the effects of different mycotoxins on maternal and fetal health and to guide public health policies and interventions. © 2020, The Author(s)

Accommodative anomalies in symptomatic school children in Cape Coast Metropolis, Ghana

Accommodative anomalies even though have been associated with an increased risk of academic failure in the pediatric population, yet have been underappreciated in African populations. This prospective cross sectional study which conformed to the Code of Ethics of the World Medical Association (Declaration of Helsinki) aimed to determine the frequencies of accommodative anomalies among symptomatic Junior High school children in the Cape Coast metropolis, Ghana.Accommodative assessment (testing for amplitude of accommodation, accommodative lag, accommodative facility, and negative and positive relative accommodation) was conducted over best corrected refraction results in a multi-stage sample of 202 symptomatic school children age ranged 12 to 17 years old. Descriptive data was analyzed using frequencies, percentages, means and standard deviations. Binary logistic regression was used to test associations between outcome variables. Of the symptomatic participants (202) assessed, 38 (18.8%) were diagnosed with ametropia, with the most frequent type being astigmatism 19 (9.4%). A number of 104 (51.5 %) symptomatic participants were diagnosed with accommodative anomaly. The frequency of specific accommodative anomalies among symptomatic Junior High school children was as follows: accommodative insufficiency, 45 (22.3%); accommodative infacility, 22(10.9%); accommodative excess, 27(13.4%) and accommodative fatigue, 10 (5%). Participants with accommodative anomalies had greater odds of experiencing symptoms of visual fatigue associated with near work (OR =0.530, p= 0.001) compared with other symptoms. The study results indicate a high prevalence of accommodative anomalies on this symptomatic school going population in Ghana and this can impact negatively on their academic performance.Keywords: Accommodative disorders, ametropia, asthenopic symptom, school children, Ghan

Molecular confirmation of Lassa fever imported into Ghana

Background: Recent reports have shown an expansion of Lassa virus from the area where it was first isolated in Nigeria to other areas of West Africa. Two Ghanaian soldiers on a United Nations peacekeeping mission in Liberia were taken ill with viral haemorrhagic fever syndrome following the death of a sick colleague and were referred to a military hospital in Accra, Ghana, in May 2013. Blood samples from the soldiers and five asymptomatic close contacts were subjected to laboratory investigations. Objective: We report the results of these investigations to highlight the importance of molecular diagnostic applications and the need for heightened awareness about Lassa fever in West Africa. Methods: We used molecular assays on sera from the two patients to identify the causativeorganism. Upon detection of positive signals for Lassa virus ribonucleic material by two differentpolymerase chain reaction assays, sequencing and phylogenetic analyses were performed. Results: The presence of Lassa virus in the soldiers’ blood samples was shown by L-gene segment homology to be the Macenta and las803792 strains previously isolated in Liberia, with close relationships then confirmed by phylogenetic tree construction. The five asymptomatic close contacts were negative for Lassa virus. Conclusions: The Lassa virus strains identified in the two Ghanaian soldiers had molecular epidemiological links to strains from Liberia. Lassa virus was probably responsible for the outbreak of viral haemorrhagic fever in the military camp. These data confirm Lassa fever endemicity in West Africa