7,298 research outputs found
Formation of PAHs and Carbonaceous Solids in Gas-Phase Condensation Experiments
Carbonaceous grains represent a major component of cosmic dust. In order to
understand their formation pathways, they have been prepared in the laboratory
by gas-phase condensation reactions such as laser pyrolysis and laser ablation.
Our studies demonstrate that the temperature in the condensation zone
determines the formation pathway of carbonaceous particles. At temperatures
lower than 1700 K, the condensation by-products are mainly polycyclic aromatic
hydrocarbons (PAHs), that are also the precursors or building blocks for the
condensing soot grains. The low-temperature condensates contain PAH mixtures
that are mainly composed of volatile 3-5 ring systems. At condensation
temperatures higher than 3500 K, fullerene-like carbon grains and fullerene
compounds are formed. Fullerene fragments or complete fullerenes equip the
nucleating particles. Fullerenes can be identified as soluble components.
Consequently, condensation products in cool and hot astrophysical environments
such as cool and hot AGB stars or Wolf Rayet stars should be different and
should have distinct spectral properties.Comment: 7 pages, 5 figure
Fabrication and Characterization of Topological Insulator BiSe Nanocrystals
In the recently discovered class of materials known as topological
insulators, the presence of strong spin-orbit coupling causes certain
topological invariants in the bulk to differ from their values in vacuum. The
sudden change of invariants at the interface results in metallic, time reversal
invariant surface states whose properties are useful for applications in
spintronics and quantum computation. However, a key challenge is to fabricate
these materials on the nanoscale appropriate for devices and probing the
surface. To this end we have produced 2 nm thick nanocrystals of the
topological insulator BiSe via mechanical exfoliation. For crystals
thinner than 10 nm we observe the emergence of an additional mode in the Raman
spectrum. The emergent mode intensity together with the other results presented
here provide a recipe for production and thickness characterization of
BiSe nanocrystals.Comment: 4 pages, 3 figures (accepted for publication in Applied Physics
Letters
Role of twin boundaries on the vortex dynamics in YBaCuO
By means of a novel technique of rotating the applied current we have
directly measured the influence of twin boundaries on the vortex motion in a
YBaCuO single crystal. The results indicate that the effect of twin
planes on the vortex dynamics starts to develop below a certain temperature,
being responsible for an anisotropic viscosity in the vortex liquid state and a
guided motion in the solid state.Comment: 4 pages, 4 figure
Dynamics of Electric Field Domains and Oscillations of the Photocurrent in a Simple Superlattice Model
A discrete model is introduced to account for the time-periodic oscillations
of the photocurrent in a superlattice observed by Kwok et al, in an undoped 40
period AlAs/GaAs superlattice. Basic ingredients are an effective negative
differential resistance due to the sequential resonant tunneling of the
photoexcited carriers through the potential barriers, and a rate equation for
the holes that incorporates photogeneration and recombination. The
photoexciting laser acts as a damping factor ending the oscillations when its
power is large enough. The model explains: (i) the known oscillatory static I-V
characteristic curve through the formation of a domain wall connecting high and
low electric field domains, and (ii) the photocurrent and photoluminescence
time-dependent oscillations after the domain wall is formed. In our model, they
arise from the combined motion of the wall and the shift of the values of the
electric field at the domains. Up to a certain value of the photoexcitation,
the non-uniform field profile with two domains turns out to be metastable:
after the photocurrent oscillations have ceased, the field profile slowly
relaxes toward the uniform stationary solution (which is reached on a much
longer time scale). Multiple stability of stationary states and hysteresis are
also found. An interpretation of the oscillations in the photoluminescence
spectrum is also given.Comment: 34 pages, REVTeX 3.0, 10 figures upon request, MA/UC3M/07/9
Optically Thick Radio Cores of Narrow-Waist Bipolar Nebulae
We report our search for optically thick radio cores in sixteen narrow-waist
bipolar nebulae. Optically thick cores are a characteristic signature of
collimated ionized winds. Eleven northern nebulae were observed with the Very
Large Array (VLA) at 1.3 cm and 0.7 cm, and five southern nebulae were observed
with the Australia Telescope Compact Array (ATCA) at 6 cm and 3.6 cm. Two
northern objects, 19W32 and M 1-91, and three southern objects, He 2-25, He
2-84 and Mz 3, were found to exhibit a compact radio core with a rising
spectrum consistent with an ionized jet. Such jets have been seen in M 2-9 and
may be responsible for shaping bipolar structure in planetary nebulae.Comment: 29 pages, accepted for publication in Ap
Chaotic dynamics of electric-field domains in periodically driven superlattices
Self-sustained time-dependent current oscillations under dc voltage bias have
been observed in recent experiments on n-doped semiconductor superlattices with
sequential resonant tunneling. The current oscillations are caused by the
motion and recycling of the domain wall separating low- and high-electric-
field regions of the superlattice, as the analysis of a discrete drift model
shows and experimental evidence supports. Numerical simulation shows that
different nonlinear dynamical regimes of the domain wall appear when an
external microwave signal is superimposed on the dc bias and its driving
frequency and driving amplitude vary. On the frequency - amplitude parameter
plane, there are regions of entrainment and quasiperiodicity forming Arnol'd
tongues. Chaos is demonstrated to appear at the boundaries of the tongues and
in the regions where they overlap. Coexistence of up to four electric-field
domains randomly nucleated in space is detected under ac+dc driving.Comment: 9 pages, LaTex, RevTex. 12 uuencoded figures (1.8M) should be
requested by e-mail from the autho
Microtubule cross-linking triggers the directional motility of kinesin-5
Although assembly of the mitotic spindle is known to be a precisely controlled process, regulation of the key motor proteins involved remains poorly understood. In eukaryotes, homotetrameric kinesin-5 motors are required for bipolar spindle formation. Eg5, the vertebrate kinesin-5, has two modes of motion: an adenosine triphosphate (ATP)–dependent directional mode and a diffusive mode that does not require ATP hydrolysis. We use single-molecule experiments to examine how the switching between these modes is controlled. We find that Eg5 diffuses along individual microtubules without detectable directional bias at close to physiological ionic strength. Eg5's motility becomes directional when bound between two microtubules. Such activation through binding cargo, which, for Eg5, is a second microtubule, is analogous to known mechanisms for other kinesins. In the spindle, this might allow Eg5 to diffuse on single microtubules without hydrolyzing ATP until the motor is activated by binding to another microtubule. This mechanism would increase energy and filament cross-linking efficiency
IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline
Alzheimer’s disease (AD) is a devastating condition with no known effective treatment. AD is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment. Emerging evidence suggests that the innate immune response plays a major role in the pathogenesis of AD. In AD, the accumulation of β-amyloid (Aβ) in the brain perturbs physiological functions of the brain, including synaptic and neuronal dysfunction, microglial activation, and neuronal loss. Serum levels of soluble ST2 (sST2), a decoy receptor for interleukin (IL)-33, increase in patients with mild cognitive impairment, suggesting that impaired IL-33/ST2 signaling may contribute to the pathogenesis of AD. Therefore, we investigated the potential therapeutic role of IL-33 in AD, using transgenic mouse models. Here we report that IL-33 administration reverses synaptic plasticity impairment and memory deficits in APP/PS1 mice. IL-33 administration reduces soluble Aβ levels and amyloid plaque deposition by promoting the recruitment and Aβ phagocytic activity of microglia; this is mediated by ST2/p38 signaling activation. Furthermore, IL-33 injection modulates the innate immune response by polarizing microglia/macrophages toward an antiinflammatory phenotype and reducing the expression of proinflammatory genes, including IL-1β, IL-6, and NLRP3, in the cortices of APP/PS1 mice. Collectively, our results demonstrate a potential therapeutic role for IL-33 in AD
First order phase transition of the vortex lattice in twinned YBa2Cu3O7 single crystals in tilted magnetic fields
We present an exhaustive analysis of transport measurements performed in
twinned YBa2Cu3O7 single crystals which stablishes that the vortex solid-liquid
transition is first order when the magnetic field H is applied at an angle
theta away from the direction of the twin planes. We show that the resistive
transitions are hysteretic and the V-I curves are non-linear, displaying a
characteristic s-shape at the melting line Hm(T), which scales as
epsilon(theta)Hm(T,theta). These features are gradually lost when the critical
point H*(theta) is approached. Above H*(theta) the V-I characteristics show a
linear response in the experimentally accessible V-I window, and the transition
becomes reversible. Finally we show that the first order phase transition takes
place between a highly correlated vortex liquid in the field direction and a
solid state of unknown symmetry. As a consequence, the available data support
the scenario for a vortex-line melting rather than a vortex sublimation as
recently suggested [T.Sasagawa et al. PRL 80, 4297 (1998)].Comment: 10 pages, 8 figures, submitted to PR
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