Driver Attitudes and Choices: Speed Limits, Seat Belt Use, and Drinking-and-Driving

A better understanding of attitudes and behavioral principles underlying driving behavior and traffic safety issues can contribute to design and policy solutions, such as speed limits and seat belt legislation. This work examines the Motor Vehicle Occupant Safety Surveys (MVOSS) dataset to illuminate drivers' seatbelt use, driving speed choices, drinking-and-driving tendencies, along with their attitudes towards speed limits and seat belt laws. Ordered probit, negative binomial, and linear regression models were used for the data analysis, and several interesting results emerged. The number and variety of results feasible with this single dataset are instructive as well as intriguing

FDTD Analysis of Electromagnetic Wave Propagation in an Inhomogeneous Ionosphere under Arbitrary-Direction Geomagnetic Field

The finite-difference time-domain (FDTD) model was developed to analyze electromagnetic (EM) wave propagation in an inhomogeneous ionosphere. The EM analysis of ionosphere is complicated, owing to various propagation environments that are significantly influenced by plasma frequency, cyclotron frequency, and collision frequency. Based on the simple auxiliary differential equation (ADE) technique, we present an accurate FDTD algorithm suitable for the EM analysis of complex phenomena in the ionosphere under arbitrary-direction geomagnetic field. Numerical examples are used to validate our FDTD model in terms of the reflection coefficient of a single magnetized plasma slab. Based on the FDTD formulation developed here, we investigate EM wave propagation characteristics in the ionosphere using realistic ionospheric data for South Korea

A case of hemocholecyst associated with hemobilia following radiofrequency ablation therapy for hepatocellular carcinoma

Radiofrequency ablation (RFA) is performed as an alternative to surgical resection for primary or secondary liver malignancies. Although RFA can be performed safely in most patients, early and late complications related to mechanical or thermal damage occur in 8-9.5% cases. Hemocholecyst, which refers to hemorrhage of the gallbladder, has been reported with primary gallbladder disease or as a secondary event associated with hemobilia. Hemobilia, defined as hemorrhage in the biliary tract and most commonly associated with accidental or iatrogenic trauma, is a rare complication of RFA. Here we report a case of hemocholecyst associated with hemobilia after RFA for hepatocellular carcinoma that was successfully managed by laparoscopic cholecystectomy

Development of the Phosphorus Recovery System (PRS) Utilizing Ultrasonic Wave in Incinerated Sewage Sludge Ash (ISSA)

This study was performed to develop a Phosphorus Recovery System(PRS) for the recovery of phosphorus from incinerated sewage sludge ash using struvite precipitation. Fly ash generated at the Seonam Sewage Treatment Plant(SSTP) has a high P2O5 content (13.9%). We developed a PRS consisting of an ultrasonic extractor, solid-liquid separator, mixing tank, and phosphorus recovery tank. The ultrasonic extractor had a 28 kHz vibrator for high speed and efficiency, which could perform the extraction in one-quarter of the time required in the conventional stirring method. Results of tests on the ultrasonic extractor showed that up to 0.044 g of P per gram of ash could be extracted with 1 N NaOH at an L/S ratio of 10 mL/g and an ultrasonic output of 500 Wh for 0.5 hr. The PRS is needed to improve the operation method and economic analysis to commercialize the technology and its application through further studies

Activation of PERK Signaling Attenuates Aβ-Mediated ER Stress

Alzheimer's disease (AD) is characterized by the deposition of aggregated beta-amyloid (Aβ), which triggers a cellular stress response called the unfolded protein response (UPR). The UPR signaling pathway is a cellular defense system for dealing with the accumulation of misfolded proteins but switches to apoptosis when endoplasmic reticulum (ER) stress is prolonged. ER stress is involved in neurodegenerative diseases including AD, but the molecular mechanisms of ER stress-mediated Aβ neurotoxicity still remain unknown. Here, we show that treatment of Aβ triggers the UPR in the SK-N-SH human neuroblastoma cells. Aβ mediated UPR pathway accompanies the activation of protective pathways such as Grp78/Bip and PERK-eIF2α pathway, as well as the apoptotic pathways of the UPR such as CHOP and caspase-4. Knockdown of PERK enhances Aβ neurotoxicity through reducing the activation of eIF2α and Grp8/Bip in neurons. Salubrinal, an activator of the eIF2α pathway, significantly increased the Grp78/Bip ER chaperone resulted in attenuating caspase-4 dependent apoptosis in Aβ treated neurons. These results indicate that PERK-eIF2α pathway is a potential target for therapeutic applications in neurodegenerative diseases including AD