Developing a Data Management Plan for a Corporate Laboratory: Using a Case Study Method for Teaching

This poster looks at the importance of developing a Data Management Plan (DMP) in the biological sciences. Grant applications increasingly require applicants to attach a DMP to their research proposals to outline the creation, storage, and dissemination of research data and information. One way to understand and assess a corporation\u27s current DMP is to use the case study method, and this poster will walk through a DMP using this research method. This particular case study looks at the industrail scientific research process and how data is created, named, and stored, with attention to record keeping deficiencies and prospects. It also looks at the issues surrounding animal experimentation

Adolescent vulnerability, sexual health, and the NP’s role in health advocacy

PurposeTo describe adolescents as a vulnerable population with unique healthcare needs, especially in relation to their sexual risk‐taking behaviors; and to explicate the necessity of nurse practitioners (NPs) advocating for youth‐friendly services and policies to meet adolescents’ sexual and reproductive healthcare needs.Data sourcesCINAHL, Medline, PsychInfo, and PsychArticle databases were searched to identify theoretical and empirical literature regarding adolescence, vulnerability, sexual health outcomes, barriers to accessing reproductive health services, what it means to be youth friendly, and health advocacy to meet the health needs of adolescents.ConclusionsAdolescents’ health needs may not be fully met in traditional healthcare settings. Lack of access to youth‐friendly sexual and reproductive health services increases adolescents’ risks for poor health outcomes including sexually transmitted disease and unplanned pregnancy. Clinic, state, and national policies can create barriers for adolescents in obtaining sexual health services.Implications for practiceNPs are philosophically and educationally prepared to be leaders in improving adolescent health outcomes. NPs can directly provide youth‐friendly care as well as advocate for youth‐friendly practices within their health system. In addition, NPs are well positioned to be leaders in advocating for state and national policies that improve adolescents’ access to appropriate sexual and reproductive health care.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/133601/1/jaan12331.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/133601/2/jaan12331_am.pd

Evidence review and experts’ opinion on consumer acceptance of agrifood nanotechnology

Nanotechnology is becoming increasingly important for the food sector, and advances and products are already being made in the areas of food packaging and food safety. However, there are several potential issues associated with the commercialization of agricultural and food (agrifood) nanotechnology that may limit its full potential, including uncertainty about whether consumers will accept or reject its products. Thus, this study aims to better understand key variables that are likely to affect consumer acceptance of agrifood nanotechnology, so that policies and programs can be better designed to address issues important to consumers prior to market entry. Factors that may influence consumer acceptance of agrifood nanotechnology were identified by examining historical experiences with other emerging technologies in food and agriculture and eliciting the opinions of experts and stakeholders. In this work, perceived risks and benefits and trust in regulatory agencies and industry were identified as the key factors influencing consumer acceptance. Our results compare favorably with other published studies in this area, and collectively they suggest that increasing consumer knowledge of agrifood nanotechnology products;ensuring high consumer benefits; minimizing risks; and increasing trust in decision makers and producers are important for consumer acceptance and the success of the emerging agrifood nanotechnology industry

Evidence review and experts’ opinion on consumer acceptance of agrifood nanotechnology

Nanotechnology is becoming increasingly important for the food sector, and advances and products are already being made in the areas of food packaging and food safety. However, there are several potential issues associated with the commercialization of agricultural and food (agrifood) nanotechnology that may limit its full potential, including uncertainty about whether consumers will accept or reject its products. Thus, this study aims to better understand key variables that are likely to affect consumer acceptance of agrifood nanotechnology, so that policies and programs can be better designed to address issues important to consumers prior to market entry. Factors that may influence consumer acceptance of agrifood nanotechnology were identified by examining historical experiences with other emerging technologies in food and agriculture and eliciting the opinions of experts and stakeholders. In this work, perceived risks and benefits and trust in regulatory agencies and industry were identified as the key factors influencing consumer acceptance. Our results compare favorably with other published studies in this area, and collectively they suggest that increasing consumer knowledge of agrifood nanotechnology products;ensuring high consumer benefits; minimizing risks; and increasing trust in decision makers and producers are important for consumer acceptance and the success of the emerging agrifood nanotechnology industry

EEG Slow Waves in Traumatic Brain Injury: Convergent Findings in Mouse and Man

OBJECTIVE: Evidence from previous studies suggests that greater sleep pressure, in the form of EEG-based slow waves, accumulates in specific brain regions that are more active during prior waking experience. We sought to quantify the number and coherence of EEG slow waves in subjects with mild traumatic brain injury (mTBI). METHODS: We developed a method to automatically detect individual slow waves in each EEG channel, and validated this method using simulated EEG data. We then used this method to quantify EEG-based slow waves during sleep and wake states in both mouse and human subjects with mTBI. A modified coherence index that accounts for information from multiple channels was calculated as a measure of slow wave synchrony. RESULTS: Brain-injured mice showed significantly higher theta:alpha amplitude ratios and significantly more slow waves during spontaneous wakefulness and during prolonged sleep deprivation, compared to sham-injured control mice. Human subjects with mTBI showed significantly higher theta:beta amplitude ratios and significantly more EEG slow waves while awake compared to age-matched control subjects. We then quantified the global coherence index of slow waves across several EEG channels in human subjects. Individuals with mTBI showed significantly less EEG global coherence compared to control subjects while awake, but not during sleep. EEG global coherence was significantly correlated with severity of post-concussive symptoms (as assessed by the Neurobehavioral Symptom Inventory scale). CONCLUSION AND IMPLICATIONS: Taken together, our data from both mouse and human studies suggest that EEG slow wave quantity and the global coherence index of slow waves may represent a sensitive marker for the diagnosis and prognosis of mTBI and post-concussive symptoms

EEG Slow Waves in Traumatic Brain Injury: Convergent Findings in Mouse and Man

OBJECTIVE: Evidence from previous studies suggests that greater sleep pressure, in the form of EEG-based slow waves, accumulates in specific brain regions that are more active during prior waking experience. We sought to quantify the number and coherence of EEG slow waves in subjects with mild traumatic brain injury (mTBI). METHODS: We developed a method to automatically detect individual slow waves in each EEG channel, and validated this method using simulated EEG data. We then used this method to quantify EEG-based slow waves during sleep and wake states in both mouse and human subjects with mTBI. A modified coherence index that accounts for information from multiple channels was calculated as a measure of slow wave synchrony. RESULTS: Brain-injured mice showed significantly higher theta:alpha amplitude ratios and significantly more slow waves during spontaneous wakefulness and during prolonged sleep deprivation, compared to sham-injured control mice. Human subjects with mTBI showed significantly higher theta:beta amplitude ratios and significantly more EEG slow waves while awake compared to age-matched control subjects. We then quantified the global coherence index of slow waves across several EEG channels in human subjects. Individuals with mTBI showed significantly less EEG global coherence compared to control subjects while awake, but not during sleep. EEG global coherence was significantly correlated with severity of post-concussive symptoms (as assessed by the Neurobehavioral Symptom Inventory scale). CONCLUSION AND IMPLICATIONS: Taken together, our data from both mouse and human studies suggest that EEG slow wave quantity and the global coherence index of slow waves may represent a sensitive marker for the diagnosis and prognosis of mTBI and post-concussive symptoms

Nuclear Spin Relaxation for Higher Spin

We study the relaxation of a spin I that is weakly coupled to a quantum mechanical environment. Starting from the microscopic description, we derive a system of coupled relaxation equations within the adiabatic approximation. These are valid for arbitrary I and also for a general stationary non--equilibrium state of the environment. In the case of equilibrium, the stationary solution of the equations becomes the correct Boltzmannian equilibrium distribution for given spin I. The relaxation towards the stationary solution is characterized by a set of relaxation times, the longest of which can be shorter, by a factor of up to 2I, than the relaxation time in the corresponding Bloch equations calculated in the standard perturbative way.Comment: 4 pages, Latex, 2 figure