Analisis Peran Badan Permusyawaratan Desa dalam Demokratisasi Pemerintahan Desa Penaga Kecamatan Teluk Bintan Kabupaten Bintan Tahun 2014

Lahirnya Badan Permusyawaratan Desa merupakan wujud demokratisasi dalam Pemerintahan Desa dengan fungsi menampung dan menyalurkan aspirasi masyarakat, menetapkan Peraturan Desa bersama Kepala Desa serta fungsi pengawasan terhadap pelaksanan Pemerintah Desa yang dijalankan oleh Kepala Desa. Penelitian ini bertujuan untuk mengetahui bagaimana peran Badan Permusyawaratan Desa dalam proses demokratisasi Desa dan apa saja faktor yang menjadi penghambat atau pendukungnya. Pada penelitian ini konsep teori yang digunakan berdasarkan kajian Peraturan Pemerintah Nomor 72 Tahun 2005 sebagai amanat dari Undang-undang Nomor 32 Tahun 2004 dan dengan membandingkan terhadap pelaksanaan Undang-undang Nomor 6 Tahun 2014 tentang Desa di Desa Penaga. Penelitian ini merupakan kualitatif dengan teknik wawancara dan observasi. Dalam penelitian ini dapat digambarkan peran BPD sebagai fungsi legislasi dan fungsi pengawasan tidak berjalan efektif, sementara fungsi representatif sudah berjalan cukup baik. Faktor penghambat yang menjadi kendala adalah rendahnya tunjangan BPD dan status pekerjaan anggota BPD, kurang harmonisnya hubungan BPD dengan Kepala Desa, dan tidak berjalannya fungsi pengawasan BPD terhadap penyusunan dan pengelolaan APBDes

Aplikasi Teknologi Asap Cair Dalam Pengolahan Dan Pengawetan Produk Perikanan Di Pulau Mandangin [ Technology Application of Liquid Smoke in Processing and Preservation of Fishery Products in the Mandangin Island]

The increase in value-added of fishery products is one of which can be done by processing. In addition to maintaining the value of the protein in the fish raw material, it would be easier if the product is stored and increase the sale value of the fish itself. The ability to perform in the fish processing in Mandangin island is still very limited. Community service activities that have been carried out by a team of the Faculty of Fisheries and Marine Universitas Airlangga was introduce smoked fish product processing with liquid smoke,because this method easier and faster so that the products can be marketed. Liquid smoke was developed because the location is very minimal in the supply of raw materials such as firewood and coconut, so the use of liquid smoke is very appropriate. The resulting refined products are expected to be a source of protein Mandangin Island community itself and is able to become an alternative source of income for the community to increase the sale value of fishery products. Mentoring process being conducted by a team from the Faculty of Fisheries and Marine Universitas Airlangga so that the products can be marketed outside Mandangin Island or even to other areas in East Java

A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy.

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.Immunoglobulin G (IgG) formed during pregnancy against human platelet antigens (HPAs) of the fetus mediates fetal or neonatal alloimmune thrombocytopenia (FNAIT). Because antibody titer or isotype does not strictly correlate with disease severity, we investigated by mass spectrometry variations in the glycosylation at Asn297 in the IgG Fc because the composition of this glycan can be highly variable, affecting binding to phagocyte IgG-Fc receptors (FcγR). We found markedly decreased levels of core fucosylation of anti-HPA-1a-specific IgG1 from FNAIT patients (n = 48), but not in total serum IgG1. Antibodies with a low amount of fucose displayed higher binding affinity to FcγRIIIa and FcγRIIIb, but not to FcγRIIa, compared with antibodies with a high amount of Fc fucose. Consequently, these antibodies with a low amount of Fc fucose showed enhanced phagocytosis of platelets using FcγRIIIb(+) polymorphonuclear cells or FcγRIIIa(+) monocytes as effector cells, but not with FcγRIIIa(-) monocytes. In addition, the degree of anti-HPA-1a fucosylation correlated positively with the neonatal platelet counts in FNAIT, and negatively to the clinical disease severity. In contrast to the FNAIT patients, no changes in core fucosylation were observed for anti-HLA antibodies in refractory thrombocytopenia (post platelet transfusion), indicating that the level of fucosylation may be antigen dependent and/or related to the immune milieu defined by pregnancy.Sanquin/PPOC-09- 025 Landsteiner Foundation for Blood Transfusion/0721 info:eu-repo/grantAgreement/EC/FP7/27853

Stingless bee honey protects against lipopolysaccharide induced-chronic subclinical systemic inflammation and oxidative stress by modulating Nrf2, NF-κB and p38 MAPK

Background: Epidemiological and experimental studies have extensively indicated that chronic subclinical systemic inflammation (CSSI) and oxidative stress are risk factors for several chronic diseases, including cancer, arthritis, type 2 diabetes, and cardiovascular and neurodegenerative diseases. This study examined the protective effect of stingless bee honey (SBH) supplementation against lipopolysaccharide (LPS)-induced CSSI, pointing to the possible involvement of NF-κB, p38 MAPK and Nrf2 signaling. Methods: CSSI was induced in male Sprague Dawley rats by intraperitoneal injection of LPS three times per week for 28 days, and SBH (4.6 and 9.3 g/kg/day) was supplemented for 30 days. Results: LPS-induced rats showed significant leukocytosis, and elevated serum levels of CRP, TNF-α, IL-1β, IL-6, IL-8, MCP-1, malondialdehyde (MDA) and 8-hydroxy-2′-deoxyguanosine (8-OHdG), accompanied with diminished antioxidants. Treatment with SBH significantly ameliorated inflammatory markers, MDA and 8-OHdG, and enhanced antioxidants in LPS-induced rats. In addition, SBH decreased NF-κB p65 and p38 MAPK, and increased Nrf2 expression in the liver, kidney, heart and lung of LPS-induced rats. Furthermore, SBH prevented LPS-induced histological and functional alterations in the liver, kidney, heart and lung of rats. Conclusion: SBH has a substantial protective role against LPS-induced CSSI in rats mediated via amelioration of inflammation, oxidative stress and NF-κB, p38 MAPK and Nrf2 signaling

Primordialism and Voting Behavior of Malay Ethnic During the 2005-2015 Riau Islands Governor Election

This research aims to examine primordialism and voting behavior of Malay ethnic during the 2005-2015 Riau Islands governor election (Pemilihan Gubernur or Pilgub). The political phenomenon in Riau Islands seems to be different from other areas where other Malays dominate since non-Malay ethnic candidates won the governor election. This research used a qualitative method with a descriptive technique. The data were collected using in-depth interviews and direct observation. Informants were selected using a purposive sampling technique. The result found that people of Malay ethnic are open-minded. The candidates elected also can prove qualified personal and successfully leading the Malay ethnic people in moving ahead. Non-Malay ethnic won the Riau Islands (known as Kepri (Kepulauan Riau)) governor election determined by 1) The political identity of Malay ethnic people is open-minded, coexisting Islamic identity, speaking Malay language, practicing Malay culture, and committing to build and develop Malay ethnic people, so the candidates identified as part of Malay ethnic people and considered by the Malay ethnic people as a candidate for leader of the Malay people in a broadening sense; 2) the figure of candidates can socialize with people of Malay ethnic; 3) other minority ethnics and political parties supported the candidates. Native Malay candidates were failed due to the lack of contribution to the people of Malay ethnic in particular and the Riau Islands in general

Analisis Potensi Sonneratia SP. Di Wilayah Pesisir Pantai Timur Surabaya Melalui Pendekatan Ekologi Dan Sosial-Ekonomi [Potency Analysis of Sonneratia SP. at East Coast Surabaya Through Ecology and Social Economy Studies]

The damages in mangrove forest recently rise due to the exploitation, either in farming or housing. It can cause the loss of mangrove function as marine ecosystem, affect marine biota survival, environment damage and reduce fishermen income in the future. For solving these problems, some efforts can be done by maximize the mangrove forest potential. Mangrove economic value analysis was done through two approaches. The first was Direct Use Value which use for knowing the benefit of the mangrove directly. The second was statistic analysis by multiple linear regression. The result of the research shows as many as 20 % of respondent make use of Sonneratia directly, either fruits, leaves or woods. Others, as many as 80% of respondents felt the benefit of Sonneratia indirectly. The research was done at mangrove forest of the Surabaya East Coast, East Java, Indonesia